AgRP

By Targets:	GPR171 (1) Melanocortin Receptor (3) Small Interfering RNA (siRNA) (3)
By Research Areas:	Metabolic Disease (1) Neurological Disease (4)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3561A

*Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)*	Melanocortin Receptor	Neurological Disease
Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake .

HY-116797

MS15203 MS0015203	GPR171	Metabolic Disease
MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP .

HY-RS24198

Agrp Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Agrp Rat Pre-designed siRNA Set A contains three designed siRNAs for Agrp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Agrp Rat Pre-designed siRNA Set A Agrp Rat Pre-designed siRNA Set A

HY-RS17733

Agrp Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
Agrp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Agrp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Agrp Mouse Pre-designed siRNA Set A Agrp Mouse Pre-designed siRNA Set A

HY-RS00465

AGRP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
AGRP Human Pre-designed siRNA Set A contains three designed siRNAs for AGRP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

AGRP Human Pre-designed siRNA Set A AGRP Human Pre-designed siRNA Set A

HY-P3924

Agouti-Related Protein (54-82) (human) AgRP (54-82) (human)	Melanocortin Receptor	Neurological Disease
Agouti-Related Protein (54-82) (human) (AGRP (54-82) (human)) is an amino-terminal 54-82 fragment of agouti-related protein (AGRP) .

HY-P3561

*Agouti-related Protein (AGRP) (83-132) Amide (human)*	Melanocortin Receptor	Neurological Disease
Agouti-related Protein (AGRP) (83-132) Amide (human) is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake .

Cat. No.	Product Name	Target	Research Area

HY-P3561A

*Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)*	Melanocortin Receptor	Neurological Disease
Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake .

HY-P3923

Agouti-Related Protein (25-51) (human) AgRP (25-51) (human)	Peptides	Neurological Disease
Agouti-Related Protein (25-51) (human) (AGRP (25-51) (human)) is an amino-terminal 25-51 fragment of agouti-related protein (AGRP) .

HY-P3924

Agouti-Related Protein (54-82) (human) AgRP (54-82) (human)	Melanocortin Receptor	Neurological Disease
Agouti-Related Protein (54-82) (human) (AGRP (54-82) (human)) is an amino-terminal 54-82 fragment of agouti-related protein (AGRP) .

HY-P3561

*Agouti-related Protein (AGRP) (83-132) Amide (human)*	Melanocortin Receptor	Neurological Disease
Agouti-related Protein (AGRP) (83-132) Amide (human) is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake .

Species:	Human (3) Rhesus Macaque (1) Mouse (3)
Tag:	His (2) Fc (5)
Source:	HEK293 (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P75526

	AGRP Protein, Human (HEK293, His) Agouti-related protein; AgRP; AGRT; ART	Human	HEK293
	AGRP proteins critically regulate body weight homeostasis and feeding behavior through the central melanocortin system. As an α-melanocyte-stimulating hormone antagonist, AGRP inhibits cAMP production and antagonizes stimulation of melanocortin receptors. AGRP Protein, Human (HEK293, His) is the recombinant human-derived AGRP protein, expressed by HEK293 , with C-His labeled tag.

HY-P75524

	AGRP Protein, Mouse (50a.a, HEK293, Fc) Agouti-related protein; AgRP; AGRT; ART	Mouse	HEK293
	The AGRP protein, encoded by the AGRP gene, regulates feeding behavior and body weight. It acts as a melanocortin receptor signaling antagonist, influencing appetite and metabolic balance. AGRP has multiple splice variants, adding to its regulatory complexity. Its expression extends beyond the central nervous system, with presence in tissues like the testis and placenta, indicating systemic involvement in physiological processes. AGRP Protein, Mouse (50a.a, HEK293, Fc) is the recombinant mouse-derived AGRP protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P75523

	AGRP Protein, Mouse (HEK293, His) Agouti-related protein; AgRP; AGRT; ART	Mouse	HEK293
	The AGRP protein is critical for body weight homeostasis and regulates feeding behavior through the central melanocortin system. As an antagonist of alpha melanocyte-stimulating hormone, AGRP inhibits cAMP production through melanocortin receptors in the hypothalamus and adrenal glands. AGRP Protein, Mouse (HEK293, His) is the recombinant mouse-derived AGRP protein, expressed by HEK293 , with C-His labeled tag.

HY-P75525

	AGRP Protein, Mouse (HEK293, Fc) Agouti-related protein; AgRP; AGRT; ART	Mouse	HEK293
	The AGRP protein is critical for body weight homeostasis and regulates feeding behavior through the central melanocortin system. As an antagonist of alpha melanocyte-stimulating hormone, AGRP inhibits cAMP production through melanocortin receptors in the hypothalamus and adrenal glands. AGRP Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived AGRP protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75528

	AGRP Protein, Human (HEK293, Fc) Agouti-related protein; AgRP; AGRT; ART	Human	HEK293
	AGRP proteins critically regulate body weight homeostasis and feeding behavior through the central melanocortin system. As an α-melanocyte-stimulating hormone antagonist, AGRP inhibits cAMP production and antagonizes stimulation of melanocortin receptors. AGRP Protein, Human (HEK293, Fc) is the recombinant human-derived AGRP protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75566

	AGRP Protein, Rhesus Macaque (HEK293, Fc) Agouti-related protein; AgRP; AGRT; ART	Rhesus Macaque	HEK293
	AGRP protein is an alpha-melanocyte stimulating hormone antagonist that regulates feeding behavior through the central melanocortin system to maintain body weight balance. AGRP inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal glands. AGRP can act as an inhibitor of MC3R and MC4R. AGRP Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived AGRP protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P75527

	AGRP Protein, Human (48a.a, HEK293, Fc) Agouti-related protein; AgRP; AGRT; ART	Human	HEK293
	AGRP proteins critically regulate body weight homeostasis and feeding behavior through the central melanocortin system. As an α-melanocyte-stimulating hormone antagonist, AGRP inhibits cAMP production and antagonizes stimulation of melanocortin receptors. AGRP Protein, Human (48a.a, HEK293, Fc) is the recombinant human-derived AGRP protein, expressed by HEK293 , with N-hFc labeled tag.

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Cat. No.	Product Name		Classification

HY-RS24198

Agrp Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Agrp Rat Pre-designed siRNA Set A contains three designed siRNAs for Agrp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17733

Agrp Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Agrp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Agrp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS00465

AGRP Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
AGRP Human Pre-designed siRNA Set A contains three designed siRNAs for AGRP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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