Search Result

Results for "

Ala-Ala-Ala

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Amino Acid Derivatives (2) AMPK (1) Antibiotic (2) Bacterial (6) Biochemical Assay Reagents (1) Complement System (1) CRFR (3) Elastase (1) Fluorescent Dye (1) Fungal (7) MAPKAPK2 (MK2) (1) MARCKS (2) MDM-2/p53 (1) PKC (2) Potassium Channel (1) Prion Protein (1) PROTACs (1) Salt-inducible Kinase (SIK) (1) Tau Protein (1) Thrombin (1) TMV (1) Transmembrane Glycoprotein (1) α-synuclein (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (4) Endocrinology (3) Infection (10) Inflammation/Immunology (7) Neurological Disease (8)

By Targets:

ADC Linker (1)

Amino Acid Derivatives (2)

AMPK (1)

Antibiotic (2)

Bacterial (6)

Biochemical Assay Reagents (1)

Complement System (1)

CRFR (3)

Elastase (1)

Fluorescent Dye (1)

Fungal (7)

MAPKAPK2 (MK2) (1)

MARCKS (2)

MDM-2/p53 (1)

PKC (2)

Potassium Channel (1)

Prion Protein (1)

PROTACs (1)

Salt-inducible Kinase (SIK) (1)

Tau Protein (1)

Thrombin (1)

TMV (1)

Transmembrane Glycoprotein (1)

α-synuclein (2)

By Research Areas:

Cancer (7)

Cardiovascular Disease (4)

Endocrinology (3)

Infection (10)

Inflammation/Immunology (7)

Neurological Disease (8)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4210

Sulanemadlin ALRN-6924; MP-4897	MDM-2/p53	Cancer
Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .

HY-W013460

*Ala-Ala-Ala*	Amino Acid Derivatives	Others
Ala-Ala-Ala is an alanine derivative .

HY-P3558

Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met	Amino Acid Derivatives	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met

HY-P4350

*Suc-Ala-Ala-Ala-AMC*	Elastase	Others
Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like .

HY-P4353

*D-{Ala-Ala-Ala}*	Bacterial	Others
D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations .

HY-P3106

*(Z-Ala-Ala-Ala-Ala)2Rh110* (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-Alanyl-L-arginine amide Rhodamine 110	Fluorescent Dye	Others
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.

HY-160714

*Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH*	ADC Linker	Cancer
Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (Compound IM-3) is a cleavable ADC linker .

HY-P10546

Polyalanine peptide pAla	Bacterial	Infection
Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research .

HY-P1100

PM102 HepArrest	Thrombin	Cardiovascular Disease
PM102 (HepArrest) is a heparin antagonist that can reverses the anticoagulant effect of heparin. PM102 potently binds heparin (Kd = 36 nM) in vitro .

HY-P3248

J5 peptide Myelin basic protein (85-99) antagonist	Biochemical Assay Reagents	Inflammation/Immunology
J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP_85-99 to HLA-DR2. J5 peptide alleviates PLP_139-151/MBP_85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases .

HY-P0305

PrP (106-126) Prion protein (106-126)	Prion Protein	Infection
PrP (106-126) is a peptide corresponding to the prion protein (PrP) amyloidogenic region, and its biochemical properties resemble the infectious form of prion protein.

HY-P5559

ND1-YL2	PROTACs	Cancer
ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .

HY-145237

BM213 1 Publications Verification	Complement System	Cancer
BM213, a potent and selective agonist for C5aR1, shows antitumor activity in a mouse model of mammary carcinoma.

HY-P1576

AMARA peptide	Salt-inducible Kinase (SIK) AMPK	Inflammation/Immunology
AMARA peptide is a substrate for SIK and AMPK.

HY-P10183

CD36 Peptide P (139-155), Cys conjugated Cys-CD36(139-155)	Transmembrane Glycoprotein	Inflammation/Immunology
CD36 Peptide P (139-155), Cys conjugated is a Cys labelled CD36 Peptide, and can inhibit the immunoadsorption of CD36 by OKM5 .

HY-P10562

BMV Gag-(7−25)	TMV	Others
BMV Gag-(7?25) is an arginine-rich peptide with cell-penetrating ability. BMV Gag-(7?25) can be used in drug delivery and gene therapy research .

HY-P6312

ESAT6 Epitope	Bacterial	Infection
ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC₅₀=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity .

HY-P10796

YARA peptide	MAPKAPK2 (MK2)	Inflammation/Immunology
YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD) .

HY-P10218A

MANS peptide TFA	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

HY-P10218

MANS peptide	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

HY-P5588

Dermaseptin-S4	Fungal	Infection
Dermaseptin-S4 is an antimicrobial peptide derived from frog skin against filamentous fungi .

HY-P4977

Tau Peptide (74-102) (Exon 3/Insert 2 Domain)	Tau Protein	Neurological Disease
Tau Peptide (74-102) (Exon 3/Insert 2 Domain) is aTau fragment.

HY-P5587

Dermaseptin-S5	Fungal	Infection
Dermaseptin-S5 is an antimicrobial peptide derived from frog skin against filamentous fungi .

HY-P5708

Adenoregulin Dermaseptin b2	Antibiotic Fungal Bacterial	Infection
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-P0263

Dermaseptin	Bacterial Fungal Antibiotic	Infection
Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .

HY-P0263A

Dermaseptin TFA	Bacterial Fungal	Infection
Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .

HY-P5593

Dermaseptin-S2	Fungal	Infection
Dermaseptin-S2 is an antimicrobial peptide derived from frog skin against filamentous fungi .

HY-P5594

Dermaseptin-S1	Fungal	Infection
Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi .

HY-P4704

α-Synuclein (61-95) (human)	α-synuclein	Neurological Disease
α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .

HY-P4704A

α-Synuclein (61-95) (human) TFA	α-synuclein	Neurological Disease
α-Synuclein (61-95) (human) TFA is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) TFA can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .

HY-P1858

Urocortin III, mouse	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Urocortin III, mouse is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2 . Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics .

HY-P1858A

Urocortin III, mouse TFA	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2 . Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics .

HY-P3019

Urocortin III (human)	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) selectively binds to type 2 CRF receptors with K_i values of 13.5, 21.7, and >100 nM for mCRF2β, rCRF2α, and hCRF1, respectively. Urocortin III (human) mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion .

HY-P5917

Vm24-toxin Vaejovis mexicanus peptide 24	Potassium Channel	Others
Vm24-toxin is a toxin peptide that can be isolated from the Mexican scorpion Vaejovis mexicanus smithy. Vm24-toxin is an inhibitor of Kv1.3 potassium channel .

Cat. No.	Product Name	Target	Research Area

HY-P3559

Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu	Peptides	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu is a β-lipotropin peptide. Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu is a polypeptide of 8 amino acids .