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American

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bacterial (3) Bcl-2 Family (1) Cytochrome P450 (2) Endogenous Metabolite (1) Fungal (1) Isotope-Labeled Compounds (1) Opioid Receptor (1) Parasite (3) Topoisomerase (1)
By Research Areas:	Cancer (2) Endocrinology (3) Infection (7) Inflammation/Immunology (1)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7654

(-)-Epipodophyllotoxin	Apoptosis	Cancer
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI₅₀s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro .

HY-N0541

Pseudoginsenoside F11 1 Publications Verification Ginsenoside A1	Endogenous Metabolite	Others
Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice.

HY-N7093

Furaneol Strawberry furanone	Others	Others
Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .

HY-N11508

Dihydrobaicalin	Others	Others
Dihydrobaicalin is a flavonoid glycoside, which can be isolated from American skullcap (Scutellaria lateriflora L.) .

HY-114763

LP8	Cytochrome P450 Parasite	Infection
LP8 is a Pyridinyl-type CYP51 inhibitor and can be used for study of chagas disease and American trypanosomiasis .

HY-P5585

Dermaseptin-B4	Bacterial	Infection
Dermaseptin-B4 is an antimicrobial peptide derived from the skin secretions of the South American frog Phyllomedusa bicolor .

HY-N3947

Glepidotin B	Bacterial	Infection
Glepidotin B is a dihydroflavonol compound isolated from the extracts of American licorice, Glycyrrhiza lepidota (Leguminosae). Glepidotin B is an antimicrobial agent .

HY-P4816

Pseudin-2	Bacterial Fungal	Infection Inflammation/Immunology
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .

HY-129271

Deltorphin Deltorphin A; Dermenkephalin	Opioid Receptor	Others
Deltorphin (Deltorphin A; Dermenkephalin) is a biological active peptide. (Deltorphin A peptide was isolated from skin extracts of the South American frog, Phyllomedusa sauvagei. Deltorphin A is a potent and selective agonist for the delta-opioid receptor.)

HY-W778833

(Z)-11-Octadecen-1-ol	Others	Endocrinology
(Z)-11-Octadecen-1-ol is a marking secretion deposited by wasps on repeated flight paths, isolated from the paired labial glands of North American male bumblebees .

HY-117129

MK 436 MK-0436	Parasite	Infection
MK 436 (MK-0436) is a metabolite with anti-trypanosomal activity that can be isolated from dog urine, particularly effective against Trypanosoma cruzi, the pathogen responsible for Chagas disease in South America .

HY-W750129

(3E,8Z)-3,8-Tetradecadienyl acetate	Others	Endocrinology
(3E,8Z)-3,8-Tetradecadienyl acetate is an insect sex pheromone that can be isolated from unmated female South American potato tuber moths (Scrobipalpula absoluta) .

HY-N7093R

Furaneol (Standard)	Others	Others
Furaneol (Standard) is the analytical standard of Furaneol. This product is intended for research and analytical applications. Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .

HY-122481

Thaspine acetate	Topoisomerase Apoptosis Bcl-2 Family Cytochrome P450	Cancer
Thaspine acetate, an alkaloid, is a topoisomerase I and II inhibitor. Thaspine acetate induces cancer cell apoptosis. Thaspine acetate induces Bak and Bax activation, mitochondrial cytochrome c release and mitochondrial membrane permeabilization. Thaspine acetate can be isoalted from the cortex of the South American tree Croton lechleri .

HY-W336192

(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate	Others	Endocrinology
(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest .

HY-W663230

Eugenitin	Parasite	Infection
Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD₅₀=39.9 μM. Eugenitin has low cytotoxicity (IC₅₀ >131 μM) against several human cancer cell lines .

HY-W012998S1

2,3-Pentanedione-13C2	Isotope-Labeled Compounds	Others
2,3-Pentanedione- ¹³C₂ is ¹³C labeled Furaneol (HY-N7093). Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .

HY-115749

D-Luciferin 6′-methyl ether 6′-Methoxyluciferin	Others	Others
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC₅₀ of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .

HY-137173

Laidlomycin propionate	Others	Others
Laidlomycin propionate is a feed additive with the activity of improving weight gain rate and feed conversion efficiency. Laidlomycin propionate can significantly increase daily weight gain, feed intake and carcass weight of beef cattle. The use of Laidlomycin propionate can effectively reduce production costs and improve the economic benefits of the cattle industry. Laidlomycin propionate has shown different effects in multiple studies in North America, and there is also significant heterogeneity between studies .

Cat. No.	Product Name	Type

HY-115749A

(Rac)-Luciferin 6′-methyl ether sodium (Rac)-6′-Methoxyluciferin sodium	Fluorescent Dyes/Probes
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC₅₀ of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .

Cat. No.	Product Name	Target	Research Area

HY-P5585

Dermaseptin-B4	Bacterial	Infection
Dermaseptin-B4 is an antimicrobial peptide derived from the skin secretions of the South American frog Phyllomedusa bicolor .

HY-P5586

Dermaseptin-B5	Peptides	Infection
Dermaseptin-B5 is an antimicrobial peptide derived from the skin secretions of the South American frog Phyllomedusa bicolor .

HY-P4816

Pseudin-2	Bacterial Fungal	Infection Inflammation/Immunology
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .

HY-129271

Deltorphin Deltorphin A; Dermenkephalin	Opioid Receptor	Others
Deltorphin (Deltorphin A; Dermenkephalin) is a biological active peptide. (Deltorphin A peptide was isolated from skin extracts of the South American frog, Phyllomedusa sauvagei. Deltorphin A is a potent and selective agonist for the delta-opioid receptor.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7654

(-)-Epipodophyllotoxin	Structural Classification other families Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Disease Research Fields Cancer	Apoptosis
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI₅₀s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro .

HY-N0541

Pseudoginsenoside F11 1 Publications Verification Ginsenoside A1	Panax ginseng C. A. Meyer Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Plants Endogenous metabolite Disease Research Fields Araliaceae	Endogenous Metabolite
Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice.

HY-N7093

Furaneol Strawberry furanone	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Vitis vinifera cv. Zalema Other Diseases Plants Vitaceae Disease Research Fields	Others
Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .

HY-N11508

Dihydrobaicalin	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Dihydrobaicalin is a flavonoid glycoside, which can be isolated from American skullcap (Scutellaria lateriflora L.) .

HY-W778833

(Z)-11-Octadecen-1-ol	Structural Classification Natural Products Animals Source classification	Others
(Z)-11-Octadecen-1-ol is a marking secretion deposited by wasps on repeated flight paths, isolated from the paired labial glands of North American male bumblebees .

HY-W750129

(3E,8Z)-3,8-Tetradecadienyl acetate	Structural Classification Natural Products Animals Source classification	Others
(3E,8Z)-3,8-Tetradecadienyl acetate is an insect sex pheromone that can be isolated from unmated female South American potato tuber moths (Scrobipalpula absoluta) .

HY-N7093R

Furaneol (Standard)	Structural Classification Microorganisms other families Ketones, Aldehydes, Acids Source classification Vitis vinifera cv. Zalema Plants Vitaceae	Others
Furaneol (Standard) is the analytical standard of Furaneol. This product is intended for research and analytical applications. Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .

HY-W336192

(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate	Structural Classification Natural Products Animals Source classification	Others
(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest .

HY-W663230

Eugenitin	Structural Classification Natural Products Microorganisms Source classification	Parasite
Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD₅₀=39.9 μM. Eugenitin has low cytotoxicity (IC₅₀ >131 μM) against several human cancer cell lines .

Species:	Virus (2)
Tag:	His (2)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P75880

	HA/Hemagglutinin Protein, H5N2 (ACF47563, HEK293, His) Influenza A H5N2 (A/American green-winged teal/California/HKWF609/2007) Hemagglutinin / HA Protein (His)	Virus	HEK293
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. HA/Hemagglutinin Protein, H5N2 (ACF47563, HEK293, His) is the recombinant Virus-derived HA/Hemagglutinin protein, expressed by HEK293 , with C-His labeled tag.

HY-P74945

	HA1/Hemagglutinin Protein, H5N2 (ACF47563, HEK293, His) Influenza A H5N2 (A/American green-winged teal/California/HKWF609/2007) Hemagglutinin Protein (HA1 Subunit) (His)	Virus	HEK293
	The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways.As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane.HA1/Hemagglutinin Protein, H5N2 (ACF47563, HEK293, His) is the recombinant Virus-derived HA1/Hemagglutinin protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W012998S1

2,3-Pentanedione-13C2
2,3-Pentanedione- ¹³C₂ is ¹³C labeled Furaneol (HY-N7093). Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .

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American

Inhibitors & Agonists

Fluorescent Dye

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products