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Results for "

Aspergillus fumigatus

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

4

Peptides

18

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164620

    Fungal Infection
    Antifungal agent 112 (Compound 1e) exhibits antifungal activity against Candida albicans, Aspergillus niger and Aspergillus fumigatus with MIC of 0.0024, 0.0022 and 0.0028 M, respectively .
    Antifungal agent 112
  • HY-W068682

    Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin

    Amylases Bacterial Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for α-Amylase with an IC50 of 3.1 μg/mL . 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549, 1321N1 and RAW264.7, antifungal and antibacterial activity against strains Candida albicans, Aspergillus fumigatus, Escherichia coli and Xanthomonas campestris .
    1-Hydroxyphenazine
  • HY-104029

    F901318

    Fungal Dihydroorotate Dehydrogenase Infection
    Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. .
    Olorofim
  • HY-126657

    Fungal Infection
    Fumigaclavine A, a clavine alkaloid, is a Mycotoxin produced by Aspergillus fumigatus. A. fumigatus can be isolated from contaminating moldy silage .
    Fumigaclavine A
  • HY-W077257

    Endogenous Metabolite Others
    5-Bromo-DL-tryptophan is a natural product which can be obtained from Aspergillus fumigatus .
    5-Bromo-DL-tryptophan
  • HY-19404

    CS-758; R-120758

    Fungal Infection
    Embeconazole (CS-758; R-120758) is an antifungal agent against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Aspergillus flavus, with MICs of 8, 16, 63 and 250 μM, respectively .
    Embeconazole
  • HY-146464

    Fungal Infection
    Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51 .
    Antifungal agent 30
  • HY-P5569

    Fungal Infection
    SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus
    SP-B peptide
  • HY-121254

    Acyltransferase Cancer
    GERI-BP002-A is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) produced by Aspergillus fumigatus F93, which can be used in cancer research .
    GERI-BP002-A
  • HY-133101

    Endogenous Metabolite Cancer
    14-Norpseurotin is a compound isolated from the culture of Aspergillus fumigatus. 14-Norpseurotin significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration .
    14-Norpseurotin
  • HY-N7569

    Apoptosis Caspase PPAR Cancer
    Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage .
    Demethoxyfumitremorgin C
  • HY-N8406

    Bacterial Antibiotic Infection
    Monomethylsulochrin is a potent antibacterial metabolite from endophytic fungus Aspergillus fumigatus, isolated from Albizia lucidior leaves (fabaceae). Monomethylsulochrin exhibits anti-Staphylococcus aureus activity with minimum inhibitory concentration (MIC) of 31.25 μg/mL .
    Monomethylsulochrin
  • HY-170616

    Fungal Interleukin Related Infection Inflammation/Immunology
    JH-FK-08 is an inhibitor for the serine/threonine-specific phosphatase calcineurin. JH-FK-08 exhibits antifungal activity that inhibits C. neoformans with MIC80 of 0.8 µg/mL. JH-FK-08 exhibits immunosuppressive activity and inhibits the IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 exhibits anti-infectious activity in mouse models .
    JH-FK-08
  • HY-117766

    Fungal Cytochrome P450 Infection
    PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively .
    PC945
  • HY-B0751

    Amebacilin; NSC9168

    Parasite HIV Antibiotic Infection
    Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin
  • HY-N8336

    Antibiotic Bacterial Fungal Infection Cancer
    IT-143A is an antibiotic, that exhibits antibacterial and antifungal activity against Micrococcus luteus and Aspergillus fumigatus with MIC of 6.25-25 μg/mL. IT-143A inhibits growth of cancer cell KB with an IC50 of 0.36 ng/mL .
    IT-143A
  • HY-N1063

    Xanthoxyline

    Fungal Infection Metabolic Disease
    Xanthoxylin (Xanthoxyline) can be isolated from Zanthoxylum simulans. Xanthoxylin has antifungal and antioxidant effects. The MIC of Xanthoxylin against Toxoplasma neonatorum and Aspergillus fumigatus were 50 µg/mL and 75 µg/mL, respectively. Xanthoxylin can be used in the study of anti-epileptic diseases .
    Xanthoxylin
  • HY-P0068

    HMR 3270; IP960; NXL201

    Fungal Infection
    Aminocandin (HMR 3270) is water-soluble antifungal agent of the echinocandin class with excellent activity against Aspergillus and Candida spp. .
    Aminocandin
  • HY-P2274

    Parasite Infection
    Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .
    Argifin
  • HY-N5160

    Antibiotic Fungal Infection
    Arborcandin A is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin A exhibits IC50 values of 0.25 μg/mL and 0.05 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin A has an MIC of 4-8 μg/mL against the genus Candida .
    Arborcandin A
  • HY-N5165

    Antibiotic Fungal Infection
    Arborcandin F is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC50 values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .
    Arborcandin F
  • HY-N5163

    Antibiotic Fungal Infection
    Arborcandin D is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin D exhibits IC50 values of 3 μg/mL and 0.35 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin D has an MIC of 4 μg/mL against the genus Candida .
    Arborcandin D
  • HY-N5162

    Antibiotic Fungal Infection
    Arborcandin C is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin C exhibits IC50 values of 0.15 μg/mL and 0.015 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin C has an MIC of 1-2 μg/mL against the genus Candida .
    Arborcandin C
  • HY-N5161

    Antibiotic Fungal Infection
    Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida .
    Arborcandin B
  • HY-B0751R

    Parasite HIV Antibiotic Infection
    Fumagillin (Standard) is the analytical standard of Fumagillin. This product is intended for research and analytical applications. Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin (Standard)
  • HY-N5164

    Antibiotic Fungal Infection
    Arborcandin E is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC50 values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida .
    Arborcandin E
  • HY-136153

    Fungal Infection
    Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and A.fumigatus with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively .
    Amphotericin X1
  • HY-147814

    Bacterial Fungal Infection
    KFU-127 (Compound 6b) is a broad spectrum topical antimicrobial capable of one-shot targeting of bacterial and fungal-bacterial biofilms. KFU-127 is considerably toxic for eukaryotic cells . KFU-127 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    KFU-127
  • HY-124902

    Antibiotic Fungal Bacterial Infection
    Valclavam is an antibiotic, which exhibits antibacterial and antifungal activities. Valclavam inhibits homoserine-O-succinyltransferase (EC 2.3.1.46), blocks the methionine synthesis, and thus inhibits Escherichia coli. Valclavam inhibits Saccharomyces cerevisiae through inhibition of RNA formation. Valclavam inhibits the movement and reproduction of nematode Caenorhabditis elegans.
    Valclavam
  • HY-138050

    (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol

    NO Synthase Bacterial Fungal Parasite Leukotriene Receptor Infection Inflammation/Immunology
    Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .
    Nyasol
  • HY-W104752

    Bacterial Fungal Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol (Compound 3n) is an antimicrobial and antioxidant agent, that inhibits Escherichia coli and Staphylococcus epidermidis, with MIC of 8 and 4 μg/mL. 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol exhibits antioxidant activity with IC50 of 17.47 μM using DPPH free radical-scavenging method .
    5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
  • HY-153624

    Fungal Infection
    Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety .
    Antifungal agent 59

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