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Bupropion

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Dopamine Transporter (2) Drug Metabolite (4) Isotope-Labeled Compounds (5) Monoamine Transporter (1) nAChR (3)
By Research Areas:	Inflammation/Immunology (1) Neurological Disease (7)

11

Inhibitors & Agonists

5

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Bupropion morpholinol-d6	Isotope-Labeled Compounds nAChR Dopamine Transporter	Neurological Disease
Bupropion morpholinol-d6 is the deuterated form of Bupropion morpholinol. Bupropion morpholinol is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities .

Hydroxybupropion	Drug Metabolite Adrenergic Receptor nAChR	Neurological Disease
Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC₅₀ value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist .

Bupropion morpholinol	Dopamine Transporter nAChR	Neurological Disease
Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities .

*(±)-Bupropion-(CH2)3-OH hydrochloride*	Others	Inflammation/Immunology
(±)-Bupropion-(CH2)3-OH hydrochloride (compound 3) is a hapten useful in the radioimmunoassay of Bupropion (HY-B0403) .

*rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride*	Isotope-Labeled Compounds	Others
rel-(1S,2S)-Dihydro bupropion-d₉ hydrochloride is the deuterium labeled rel-(1S,2S)-Dihydro bupropion hydrochloride.

*rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride*	Isotope-Labeled Compounds	Neurological Disease
rel-(1S,2R)-Dihydro bupropion-d₉ hydrochloride is the deuterium labeled rel-(1S,2R)-Dihydro bupropion hydrochloride .

Radafaxine (S,S)-HydroxyBupropion; GW-353162A free base; BW-306U free base	Monoamine Transporter Drug Metabolite	Neurological Disease
Radafaxine ((S,S)-Hydroxybupropion) is an antidepressant. Radafaxine blocks dopamine transporters (DAT). Radafaxine is an active metabolite of Bupropion .

*rel-(1S,2R)-Dihydro bupropion-d9*	Isotope-Labeled Compounds	Others
rel-(1S,2R)-Dihydro bupropion-d₉ is the deuterium labeled rel-(1S,2R)-Dihydro bupropion. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

*Erythro-hydro bupropion-d9 (enantiomer)(hydrochloride)*	Isotope-Labeled Compounds	Others
Erythro-hydro bupropion-d₉ (enantiomer)(hydrochloride) is deuterium labeled (1R,2S)-2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-ol hydrochloride .

Threo-dihydrobupropion hydrochloride	Drug Metabolite	Neurological Disease
Threo-dihydrobupropion hydrochloride is a primary metabolite of Bupropion. Threo-dihydrobupropion hydrochloride can be used for the research of the depression, behavioral, and biochemistry .

Threo-dihydrobupropion	Drug Metabolite	Neurological Disease
Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid .

Cat. No.	Product Name	Chemical Structure

Bupropion morpholinol-d6
Bupropion morpholinol-d6 is the deuterated form of Bupropion morpholinol. Bupropion morpholinol is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities .

*rel-(1S,2S)-Dihydro bupropion-d9 hydrochloride*
rel-(1S,2S)-Dihydro bupropion-d₉ hydrochloride is the deuterium labeled rel-(1S,2S)-Dihydro bupropion hydrochloride.

*rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride*
rel-(1S,2R)-Dihydro bupropion-d₉ hydrochloride is the deuterium labeled rel-(1S,2R)-Dihydro bupropion hydrochloride .

*rel-(1S,2R)-Dihydro bupropion-d9*
rel-(1S,2R)-Dihydro bupropion-d₉ is the deuterium labeled rel-(1S,2R)-Dihydro bupropion. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

*Erythro-hydro bupropion-d9 (enantiomer)(hydrochloride)*
Erythro-hydro bupropion-d₉ (enantiomer)(hydrochloride) is deuterium labeled (1R,2S)-2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-ol hydrochloride .

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