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Cannabinoid system

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cannabinoid Receptor (15) Apoptosis (1) Endogenous Metabolite (6) GPR55 (1) Isotope-Labeled Compounds (2)
By Research Areas:	Inflammation/Immunology (5) Neurological Disease (10)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Cannabinoid Receptor Complement System

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011051

2-Arachidonoylglycerol 1 Publications Verification	Cannabinoid Receptor Endogenous Metabolite	Neurological Disease
2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

HY-126161

Nonabine BRL-4664	Cannabinoid Receptor	Neurological Disease
Nonabine (BRL-4664), a cannabinoid, is a antiemetic agent. Nonabine activates CB1 receptor in the brainstem and enteric nervous system .

HY-W011051S1

2-Arachidonoylglycerol-d5	Cannabinoid Receptor Endogenous Metabolite	Neurological Disease
2-Arachidonoylglycerol-d₅ is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

HY-W011051S

2-Arachidonoylglycerol-d8	Cannabinoid Receptor Endogenous Metabolite	Neurological Disease
2-Arachidonoylglycerol-d₈ is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

HY-146134

PGN36	Cannabinoid Receptor	Inflammation/Immunology
PGN36 (Compound 18) is a selective cannabinoid CB₂ receptor (CB₂R) antagonist with a K_i of 0.09 µM .

HY-110016

Docosatetraenylethanolamide DEA	Endogenous Metabolite Cannabinoid Receptor	Neurological Disease
Docosatetraenylethanolamide (DEA) is a cannabinoid receptor 1 (CB1) agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a K_i value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system .

HY-W011051S2

2-Arachidonoylglycerol-d11	Isotope-Labeled Compounds Cannabinoid Receptor Endogenous Metabolite	Neurological Disease
2-Arachidonoylglycerol-d₁₁ is deuterium labeled 2-Arachidonoylglycerol.2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system[1].

HY-134173

Arachidonoyl ethanolamide phosphate	Cannabinoid Receptor Apoptosis	Neurological Disease
Arachidonoyl ethanolamide phosphate, an endocannabinoid, is an endogenous ligand for cannabinoid receptors in the central nervous system (CB1 subtype) and peripheral immune cells (CB2 subtype) .

HY-151105

CBR Agonist-1	Cannabinoid Receptor	Neurological Disease
CBR Agonist-1 (27a-cis) is a cannabinoid receptor (CBR) agonist with the K_i values of 0.18 μM for CB₁R and 1.22 μM for CB₂R. CBR Agonist-1 (27a-cis) can be used in the study of endogenous cannabinoid system-related diseases .

HY-149644

CB2R agonist 3	Cannabinoid Receptor	Inflammation/Immunology
CB2R agonist 3 is an agonist of cannabinoid receptor 2 (CB2R), with EC₅₀ of 0.37μM that plays an important role in immune system .

HY-122281

JTE 7-31	Cannabinoid Receptor	Others
JTE 7-31 selectively acts on peripheral cannabinoid receptors, minimizing central nervous system side effects. They exhibit potent immunomodulatory, anti-inflammatory and anti-allergic properties, as well as inhibitory effects on nephritis .

HY-110004

ACEA Arachidonyl-2-chloroethylamide	Cannabinoid Receptor	Others
ACEA (short for arachidonyl-2'-chloroacetamide) is a synthetic organic compound that acts as an agonist of the cannabinoid receptor CB1. It is a chemical that affects the endocannabinoid system in the body, which regulates various physiological processes such as appetite, pain perception, mood, and memory .

HY-10863S1

Anandamide-d11 AEA-d₁₁	Isotope-Labeled Compounds Cannabinoid Receptor GPR55 Endogenous Metabolite	Inflammation/Immunology
Anandamide-d₁₁ is deuterium labeled Anandamide. Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55)[1][2].

HY-103331

COR170	Cannabinoid Receptor	Neurological Disease Inflammation/Immunology
COR170 (11u) is a selective CB2 inverse-agonist which is a 4-quinolone-3-carboxylic acid derivative with a K_i value of 3.8 nM for CB2 receptor. COR170 can be used for the research of inflammation and neuroprotection .

HY-163394

CB2 receptor agonist 6	Cannabinoid Receptor	Neurological Disease Inflammation/Immunology
CB2 receptor agonist 6 (compound 70) is an agonist of CB2R, with EC₅₀ of 162 nM. The IC₅₀ values of CB2 receptor agonist 6 are 4.83 μM for CB1R and 0.88 μM for CB2R. CB2 receptor agonist 6 is a neuroprotective agent that can be used for the reseach of neurological disease .

Cat. No.	Product Name	Type

HY-110004

ACEA Arachidonyl-2-chloroethylamide	Cell Assay Reagents
ACEA (short for arachidonyl-2'-chloroacetamide) is a synthetic organic compound that acts as an agonist of the cannabinoid receptor CB1. It is a chemical that affects the endocannabinoid system in the body, which regulates various physiological processes such as appetite, pain perception, mood, and memory .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011051

2-Arachidonoylglycerol 1 Publications Verification	Structural Classification Natural Products Source classification Endogenous metabolite	Cannabinoid Receptor Endogenous Metabolite
2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

HY-110016

Docosatetraenylethanolamide DEA	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Cannabinoid Receptor
Docosatetraenylethanolamide (DEA) is a cannabinoid receptor 1 (CB1) agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a K_i value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system .

Cat. No.	Product Name	Chemical Structure

HY-W011051S1

2-Arachidonoylglycerol-d5
2-Arachidonoylglycerol-d₅ is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

HY-W011051S

2-Arachidonoylglycerol-d8
2-Arachidonoylglycerol-d₈ is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

HY-W011051S2

2-Arachidonoylglycerol-d11
2-Arachidonoylglycerol-d₁₁ is deuterium labeled 2-Arachidonoylglycerol.2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system[1].

HY-10863S1

Anandamide-d11
Anandamide-d₁₁ is deuterium labeled Anandamide. Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55)[1][2].

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Cannabinoid system

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products