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Carbapenem

" in MedChemExpress (MCE) Product Catalog:

44

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2

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6

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8

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2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0187A
    Doripenem monohydrate
    5+ Cited Publications

    S 4661 monohydrate

    		 Bacterial Antibiotic Infection
    Doripenem (S 4661) monohydrate, a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .
    Doripenem monohydrate
  • HY-B0187
    Doripenem
    5+ Cited Publications

    S 4661

    		 Bacterial Antibiotic Infection
    Doripenem (S 4661), a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .
    Doripenem
  • HY-16955A
    Plazomicin sulfate
    1 Publications Verification

    ACHN 490 sulfate

    		 Antibiotic Bacterial Infection Inflammation/Immunology
    Plazomicin (ACHN 490) sulfate is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin sulfate has in vitro activity against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin sulfate has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .
    Plazomicin sulfate
  • HY-13678
    Meropenem
    10+ Cited Publications

    SM 7338

    		 Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem
  • HY-105180
    Lenapenem

    BO-2727 free acid

    		 Bacterial Infection
    Lenapenem (BO-2727 free acid), a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa .
    Lenapenem
  • HY-16955
    Plazomicin

    ACHN 490

    		 Antibiotic Bacterial Infection Inflammation/Immunology
    Plazomicin (ACHN 490) is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin has in vitro activity against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .
    Plazomicin
  • HY-B0187AR
    Doripenem (monohydrate) (Standard)

    		Bacterial Antibiotic Infection
    Doripenem (monohydrate) (Standard) is the analytical standard of Doripenem (monohydrate). This product is intended for research and analytical applications. Doripenem (S 4661) monohydrate, a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .
    Doripenem (monohydrate) (Standard)
  • HY-123022
    Tomopenem

    CS-023; RO4908463; R-115685

    		 Bacterial Infection
    Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL). Antianaerobic activity .
    Tomopenem
  • HY-150260
    SA09-Cu

    		Bacterial Infection
    SA09-Cu is a noncompetitive and potent NDM-1 inhibitor with an IC50 of 9.6 nM. SA09-Cu can convert NDM-1 into an inactive state by oxidizing the Zn(II)-thiolate site of the enzyme and avoids to be reduced by intracellular thiols of bacteria. SA09-Cu exhibits excellent inhibition against a series of clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) in restoring the Meropenem (HY-13678) effect, and slows down the development of carbapenem resistance .
    SA09-Cu
  • HY-W740053
    Meropenem sodium

    		Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem sodium
  • HY-13678A
    Meropenem trihydrate
    10+ Cited Publications

    SM 7338 trihydrate

    		 Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem trihydrate
  • HY-13678R
    Meropenem (Standard)

    		Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem (Standard) is the analytical standard of Meropenem. This product is intended for research and analytical applications. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem (Standard)
  • HY-13678S1
    Meropenem-d6-1

    SM 7338-d6-1

    		 Bacterial Antibiotic Infection
    Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem-d6-1
  • HY-13678AR
    Meropenem (trihydrate) (Standard)

    		Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate). This product is intended for research and analytical applications. Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem (trihydrate) (Standard)
  • HY-N14182
    Asparenomycin A

    		Antibiotic Bacterial Infection
    Asparenomycin A is a carbapenem antibiotic with strong β-lactamase inhibition activities .
    Asparenomycin A
  • HY-N14185
    Asparenomycin C

    		Antibiotic Bacterial Infection
    Asparenomycin C is a carbapenem antibiotic with strong β-lactamase inhibition activities .
    Asparenomycin C
  • HY-N14183
    Asparenomycin B

    		Antibiotic Bacterial Infection
    Asparenomycin B is a carbapenem antibiotic with strong β-lactamase inhibition activities .
    Asparenomycin B
  • HY-170803
    KPC-IN-1

    		Bacterial Infection
    KPC-IN-1 (compound 1e) is an inhibitor of Klebsiella pneumoniae carbapenemase KPC-2 (IC50=8.3 nM). KPC is a β-lactamase expressed in Gram-negative bacteria that hydrolyzes carbapenems. KPC causes significant bacterial resistance to carbapenem antibiotics .
    KPC-IN-1
  • HY-137927
    Benapenem

    		Antibiotic Others
    Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.
    Benapenem
  • HY-13573
    Biapenem
    4 Publications Verification

    CLI 86815; L 627; LJC 10627

    		 Beta-lactamase Bacterial Antibiotic Infection
    Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.
    Biapenem
  • HY-A0076
    Tebipenem
    5+ Cited Publications

    LJC 11036

    		 Bacterial Antibiotic Infection
    Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.
    Tebipenem
  • HY-155202
    YJ196

    		Beta-lactamase Others
    YJ196 (Compound 59) is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor .
    YJ196
  • HY-13573R
    Biapenem (Standard)

    		Beta-lactamase Bacterial Antibiotic Infection
    Biapenem (Standard) is the analytical standard of Biapenem. This product is intended for research and analytical applications. Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.
    Biapenem (Standard)
  • HY-P5691
    P1

    		Bacterial Infection Cancer
    P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .
    P1
  • HY-A0076R
    Tebipenem (Standard)

    		Bacterial Antibiotic Infection
    Tebipenem (Standard) is the analytical standard of Tebipenem. This product is intended for research and analytical applications. Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.
    Tebipenem (Standard)
  • HY-120203
    DA 1131

    		Antibiotic Bacterial Infection
    DA 1131 is an anionic Carbapenem antibiotic. DA 1131 has broad spectrum antibacterial activity for both gram-positive and gram-negative organisms. DA 1131 is resistant to degradation by various types of β-lactamases .
    DA 1131
  • HY-W127616A
    β-Sitosterol acetate, 95%

    Sitosteryl acetate, 95%

    		 Bacterial Infection
    β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .
    β-Sitosterol acetate, 95%
  • HY-147429
    Zosurabalpin

    Abx MCP; RG6006

    		 Bacterial Antibiotic Infection
    Zosurabalpin is a polypeptide antibiotic targeting LPS transporter (LptB2FGC complex), which can block the transport of LPS and lead to endotoxin accumulation in cells, and has shown excellent antibacterial activity against Carbapenem-resistant Acinetobacter baumanni (CRAB) .
    Zosurabalpin
  • HY-B1369
    Imipenem monohydrate
    Maximum Cited Publications
    22 Publications Verification

    N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate

    		 Bacterial Antibiotic Infection
    Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
    Imipenem monohydrate
  • HY-B1369A
    Imipenem
    Maximum Cited Publications
    22 Publications Verification

    N-Formimidoyl thienamycin; MK0787

    		 Antibiotic Bacterial Infection
    Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
    Imipenem
  • HY-142619
    TP0586352

    		Bacterial Infection
    TP0586352 is a LpxC inhibitor that is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk. TP0586352 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    TP0586352
  • HY-120242
    N-(3-Oxobutanoyl)-L-homoserine lactone

    		Antibiotic Infection
    N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum .
    N-(3-Oxobutanoyl)-L-homoserine lactone
  • HY-125416
    Streptothricin F

    		Antibiotic Bacterial Infection
    Streptothricin F is a bactericidal antibiotic. Streptothricin F interacts with the 30S subunit of 70S ribosome. Streptothricin F shows rapid, bactericidal activity against highly drug-resistant, carbapenem-resistant Enterobacterales (CRE) (MIC50 and MIC90: 2 and 4 μM, respectively) and Acinetobacter baumannii .
    Streptothricin F
  • HY-W743988
    Cilastatin ammonium salt

    		Antibiotic Bacterial Infection
    Cilastatin ammonium salt is an antibiotic that is relatively effective against Gram-positive cocci with a half-life of 3-4 h .
    Cilastatin ammonium salt
  • HY-B1369R
    Imipenem monohydrate (Standard)

    		Bacterial Antibiotic Infection
    Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
    Imipenem monohydrate (Standard)
  • HY-P2331
    Actagardin

    Antibiotic A 3802-IV-3; Gardimycin

    		 Antibiotic Infection
    Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
    Actagardin
  • HY-B1369AR
    Imipenem (Standard)

    		Antibiotic Bacterial Infection
    Imipenem (Standard) is the analytical standard of Imipenem. This product is intended for research and analytical applications. Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
    Imipenem (Standard)
  • HY-147349
    ANT3310 sodium

    		Beta-lactamase Bacterial Infection
    ANT3310 sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). ANT3310 sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). ANT3310 sodium can be used in the research of bacterial infection .
    ANT3310 sodium
  • HY-13678S
    Meropenem-d6

    SM 7338-d6

    		 Bacterial Antibiotic Infection
    Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
    Meropenem-d6
  • HY-P1726
    MSG606

    		Melanocortin Receptor Neurological Disease
    MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects .
    MSG606
  • HY-P1726A
    MSG606 TFA

    		Melanocortin Receptor Cancer
    MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
    MSG606 TFA
  • HY-118013
    NDM-1 inhibitor-2

    		Bacterial Infection
    NDM-1 inhibitor-2 is an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) and has the ability to inhibit NDM-1 activity. NDM-1 inhibitor-2 exhibits a good inhibitory effect on drug-resistant bacterial strains that overexpress NDM-1. When NDM-1 inhibitor-2 is used in combination with the carbapenem antibiotic meropenem, a favorable synergistic effect can be produced .
    NDM-1 inhibitor-2
  • HY-P0041A
    F992 TFA

    		Vasopressin Receptor Neurological Disease
    F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .
    F992 TFA
  • HY-P0041
    F992

    		Vasopressin Receptor Neurological Disease
    F992 is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .
    F992

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