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Cardiolipin (16:0/18:1/16:0/18:1)

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

2

Fluorescent Dye

2

Biochemical Assay Reagents

2

Peptides

2

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2

Recombinant Proteins

5

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134238

    Endogenous Metabolite Biochemical Assay Reagents Neurological Disease
    Cardiolipin (Heart, Bovine) sodium is a mitochondria-exclusive phospholipid that can be extracted from Bovine hear. Aberrant Cardiolipin content, structure, and localization are linked to impaired neurogenesis and neuronal dysfunction, contributing to neurodegenerative diseases. Cardiolipin (Heart, Bovine) sodium can be coated on microtitre plates for ELISA assay .
    Cardiolipin (Heart, Bovine) sodium
  • HY-160202

    Bacterial Infection
    18:1 Cardiolipin disodium is a virulence regulator with two phosphate groups and four acyl chains.18:1 Cardiolipin disodium can be used in the study of the regulation and mechanism of bacterial infection .
    18:1 Cardiolipin disodium
  • HY-D0993
    Acridine Orange 10-Nonyl Bromide
    3 Publications Verification

    Nonylacridine orange

    Fluorescent Dye Others
    Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipinex: 489 nm, λem: 525 nm).
    Acridine Orange 10-Nonyl Bromide
  • HY-W013100
    Cytidine-5'-triphosphate disodium
    2 Publications Verification

    Cytidine triphosphate disodium; 5'-CTP disodium

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Metabolic Disease
    Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
    Cytidine-5'-triphosphate disodium
  • HY-168798

    Biochemical Assay Reagents Metabolic Disease
    Cardiolipin sodium is an anionic phospholipid containing the monounsaturated fatty acid Myristoleic acid (HY-113332).
    Cardiolipin sodium
  • HY-148009

    16:0-18:1 Cardiolipin sodium

    Biochemical Assay Reagents Others
    Cardiolipin (16:0/18:1/16:0/18:1) (16:0-18:1 Cardiolipin) sodium is an anionic phospholipid containing the long-chain fatty acid palmitic acid (HY-N0830) and the monounsaturated fatty acid oleic acid (HY-N1446). Cardiolipin (16:0/18:1/16:0/18:1) sodium can be used in the synthesis of lipid nanodiscs for application in in situ mass spectrometry .
    Cardiolipin (16:0/18:1/16:0/18:1) sodium
  • HY-157657

    Diphosphatidylglycerol sodium salt; 16:1 Cardiolipin sodium salt; 64:4-CL sodium salt

    Liposome Others
    Cardiolipin (16:1/16:1/16:1/16:1) sodium salt is an anionic phospholipid that promote hydroxyapatite crystallization and supersaturation in a calcium solution .
    Cardiolipin (16:1/16:1/16:1/16:1) sodium salt
  • HY-159856

    Diphosphatidylglycerol (16:0)

    Liposome Others
    16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    16:0 Cardiolipin
  • HY-157661

    1',3'-Bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol sodium

    Biochemical Assay Reagents
    14:0 Cardiolipin sodium (1',3'-Bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium)) is a kind of biochemical reagent.
    14:0 Cardiolipin sodium
  • HY-W590676

    TMCL

    Liposome Others
    Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .
    Tetramyristoylcardiolipin
  • HY-125857

    Biochemical Assay Reagents Apoptosis Reactive Oxygen Species Metabolic Disease
    Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .
    Cytochrome C
  • HY-169160

    Bacterial Infection
    Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death .
    Anti-MRSA agent 18
  • HY-116447

    Mitochondrial Metabolism Apoptosis Cancer
    Antitumor agent-159 (Compound 13b) targets the mitochondria and downregulates cardiolipin levels. Antitumor agent-159 inhibits the proliferation of cancer cell MDA-MB-231, arrests the cell cycle at sub-G1 phase, and induces apoptosis in MDA-MB-231. Antitumor agent-159 exhibits antitumor efficacy in MDA-MB-231 xenograft mouse models .
    Antitumor agent-159
  • HY-P0125
    Elamipretide
    Maximum Cited Publications
    12 Publications Verification

    MTP-131; RX-31; SS-31

    Mitochondrial Metabolism Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Elamipretide (MTP-131) is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury .
    Elamipretide
  • HY-P0125B
    Elamipretide triacetate
    Maximum Cited Publications
    12 Publications Verification

    MTP-131 triacetate; RX-31 triacetate; SS-31 triacetate

    Mitochondrial Metabolism Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Elamipretide triacetate (MTP-131 triacetate; RX-31 triacetate; SS-31 triacetate) is Elamipretide triacetate form of Elamipretide (HY-P0125). Elamipretide triacetate is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury .
    Elamipretide triacetate
  • HY-P2807J

    Lactate Dehydrogenase Metabolic Disease
    L-Lactate Dehydrogenase (L-LDH), pig muscle is an L-lactate dehydrogenase found in pig muscle, mainly present in anaerobic tissues (skeletal muscle, red blood cells). L-Lactate Dehydrogenase (L-LDH), pig muscle can interact with acidic liposomes at low pH, causing protein to adsorb onto the liposomes and inhibit enzyme activity. The IC50 values for L-Lactate Dehydrogenase (L-LDH), pig muscle are 0.05 μM for cardiolipin and 1.3 μM for phosphatidylserine liposomes .
    L-Lactate Dehydrogenase (L-LDH), pig muscle
  • HY-125623

    Fluorescent Dye Others
    MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2].
    MitoPerOx