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Results for "

Digitalis

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Biochemical Assay Reagents

7

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N12084

    Others Cancer
    Isolugrandoside is a nature product. Isolugrandoside can be isolated from Digitalis davisiana Heywood .
    Isolugrandoside
  • HY-B1238
    Pronethalol
    1 Publications Verification

    (±)-Pronethalo

    Adrenergic Receptor Cardiovascular Disease Neurological Disease
    Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cerebral arteriovenous malformation (AVMs) .
    Pronethalol
  • HY-N4000
    Digitonin
    Maximum Cited Publications
    11 Publications Verification

    Others Cancer
    Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth . Digitonin is an natural detergent .
    Digitonin
  • HY-N12799

    Digitalinum verum

    Others Others
    Digitalin (Digitalinum verum) is a cardiac glycoside and can be isolated from Digitalis .
    Digitalin
  • HY-N7328

    Others Cardiovascular Disease
    Lanatoside B is a cardenolide that can be isolated from the leaves of Digitalis lanata .
    Lanatoside B
  • HY-N12085

    Others Cancer
    Lugrandoside is a nature product. Lugrandoside can be isolated from Digitalis davisiana Heywood .
    Lugrandoside
  • HY-B1238A

    (±)-Pronethalo hydrochloride

    Adrenergic Receptor Cardiovascular Disease Neurological Disease
    Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias, and limits the cerebral arteriovenous malformation (AVMs) .
    Pronethalol hydrochloride
  • HY-N5093

    Others Cancer
    Glucodigifucoside, a cardenolide glycoside that could be isolated from the seeds of Digitalis purpurea, exhibits potent cytotoxicity against human renal adenocarcinoma cell line ACHN .
    Glucodigifucoside
  • HY-16022

    Digitoxin 3'''-Acetate

    Others Others
    Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch .
    Acetyldigitoxin
  • HY-130456

    Others Cardiovascular Disease
    AHR 10718 is an antiarrhythmic agent that suppresses cardiac arrhythmias induced by digitalis intoxication and myocardial infarction in the intact dog. AHR 10718 also depresses membrane responsiveness and conduction, shortens the effective refractory period of specialized conducting fibers less than action potential duration .
    AHR 10718
  • HY-B2151

    Cerberigenin; Echujetin

    Biochemical Assay Reagents Others
    Digitoxigenin is a steroid derivative commonly found in various plants, especially the foxglove plant (Digitalis purpurea). Digitoxigenin has unique chemical properties that make it an important precursor for the synthesis of cardiac glycosides, a group of drugs used to improve heart failure and certain types of arrhythmias. It works by inhibiting the sodium potassium ATPase pump, thereby increasing the force and efficiency of cardiac contractions.
    Digitoxigenin
  • HY-136677

    Others Cardiovascular Disease
    LND 796 is an aminosteroidal derivative with positive inotropic effects similar to those of digitalis. It exhibits electrophysiological, toxic, and inotropic effects in normal and partially potassium-depolarized ventricular muscles. LND 796 requires higher concentrations than digoxin to induce the same toxic symptoms. It exhibits a concentration-dependent positive inotropic effect on guinea pig papillary muscles in normal potassium solution. In partially potassium-depolarized papillary muscles, LND 796 enhances both components of contraction and increases the amplitude of slow action potentials. The mechanism of positive inotropic action of LND 796 involves enhanced calcium entry in calcium channels and inhibition of sodium-potassium ATPase. Due to its expanded positive inotropic range, LND 796 may have potential application in the treatment of congestive heart failure.
    Lnd 796

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