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Results for "

FGF-1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

8

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100434
    PD-161570

    		FGFR PDGFR EGFR Src TGF-β Receptor Cardiovascular Disease Cancer
    PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF-stimulated autophosphorylation and FGF-1 receptor phosphorylation with IC50s of 450 nM and 622 nM, respectively [1] . PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-β signaling inhibitor .
    PD-161570
  • HY-RS04886
    FGF1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    FGF1 Human Pre-designed siRNA Set A contains three designed siRNAs for FGF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    FGF1 Human Pre-designed siRNA Set A
    FGF1 Human Pre-designed siRNA Set A
  • HY-149352
    DG1

    		Thymidylate Synthase Cancer
    DG1 (Compound 8Nc) is a Thymidylate Synthase (TS) inhibitor that affects cancer angiogenesis and metabolic reprogramming in NSCLC cells. DG1 can effectively inhibit the expression of CD26, ET-1, FGF-1 and EGF. DG1 also effectively inhibits the proliferation of cancer tissue in the A549 xenograft mouse model [1].
    DG<em>1</em>

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