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Results for "

GAD1

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Natural
Products

1

Recombinant Proteins

4

Isotope-Labeled Compounds

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0161
    Duloxetine
    5+ Cited Publications

    LY248686

    		 Serotonin Transporter Neurological Disease Cancer
    Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
    Duloxetine
  • HY-B0161A
    Duloxetine hydrochloride
    5+ Cited Publications

    (S)-Duloxetine hydrochloride; LY-248686 hydrochloride

    		 Serotonin Transporter Neurological Disease Cancer
    Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
    Duloxetine hydrochloride
  • HY-118901
    Opipramol

    Ensidon; G-33040

    		 Sigma Receptor Neurological Disease
    Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) .
    Opipramol
  • HY-B0161S
    Duloxetine-d7

    		Isotope-Labeled Compounds Serotonin Transporter Neurological Disease
    Duloxetine-d7 ((S)-Duloxetine-d7) is the deuterium labeled Duloxetine. Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].
    Duloxetine-d7
  • HY-RS17368
    Gad1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA)
    Gad1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gad1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Gad1 Mouse Pre-designed siRNA Set A
    Gad1 Mouse Pre-designed siRNA Set A
  • HY-RS05227
    GAD1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GAD1 Human Pre-designed siRNA Set A contains three designed siRNAs for GAD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GAD1 Human Pre-designed siRNA Set A
    GAD1 Human Pre-designed siRNA Set A
  • HY-B0161AS
    Duloxetine D3 hydrochloride

    (S)-Duloxetine-d3 (hydrochloride); LY248686-d3 (hydrochloride)

    		 Serotonin Transporter Neurological Disease
    Duloxetine-d3 (hydrochloride) is a deuterium labeled Duloxetine hydrochloride. Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].
    Duloxetine D3 hydrochloride
  • HY-118901A
    Opipramol dihydrochloride

    Ensidon dihydrochloride; G-33040 dihydrochloride

    		 Sigma Receptor Neurological Disease
    Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) .
    Opipramol dihydrochloride
  • HY-B0161AR
    Duloxetine (hydrochloride) (Standard)

    (S)-Duloxetine hydrochloride (Standard); LY-248686 hydrochloride (Standard)

    		 Serotonin Transporter Neurological Disease Cancer
    Duloxetine (hydrochloride) (Standard) is the analytical standard of Duloxetine (hydrochloride). This product is intended for research and analytical applications. Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
    Duloxetine (hydrochloride) (Standard)
  • HY-B0161S3
    Duloxetine-d5 oxalate

    (S)-Duloxetine-d5 oxalate; LY248686-d5 oxalate

    		 Isotope-Labeled Compounds Serotonin Transporter Neurological Disease Cancer
    Duloxetine-d5 (oxalate) ((S)-Duloxetine-d5 (oxalate)) is deuterium labeled Duloxetine. Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
    Duloxetine-d5 oxalate
  • HY-122487
    Troriluzole

    BHV-4157

    		 mGluR Neurological Disease Cancer
    Troriluzole, a third-generation, tripeptide proagent of Riluzole (HY-B0211), is an orally active glutamate modulator. Troriluzole reduces synaptic glutamate level and increases the synaptic glutamate absorption. Troriluzole has the potential for Alzheimer disease and generalized anxiety disorder (GAD) .
    Troriluzole
  • HY-122487A
    Troriluzole hydrochloride

    BHV-4157 hydrochloride

    		 mGluR Neurological Disease
    Troriluzole hydrochloride is a third-generation peptide precursor of Riluzole (HY-B0211) and is an orally active glutamate modulator. Troriluzole hydrochloride can reduce synaptic glutamate levels and enhance the uptake of synaptic glutamate. Troriluzole hydrochloride shows potential for treating Alzheimer's disease and Generalized Anxiety Disorder (GAD) .
    Troriluzole hydrochloride
  • HY-B0161AS1
    Duloxetine-d7 hydrochloride

    (S)-Duloxetine-d7 hydrochloride; LY248686-d7 hydrochloride

    		 Isotope-Labeled Compounds Serotonin Transporter Neurological Disease Cancer
    Duloxetine-d7 hydrochloride ((S)-Duloxetine-d7 hydrochloride) is the deuterium labeled Duloxetine hydrochloride (HY-B0161A). Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
    Duloxetine-d7 hydrochloride
  • HY-118901R
    Opipramol (Standard)

    		Sigma Receptor Neurological Disease
    Opipramol (Standard) is the analytical standard of Opipramol. This product is intended for research and analytical applications. Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) .
    Opipramol (Standard)
  • HY-Y0367R
    Maleic Acid (Standard)

    		Endogenous Metabolite Bacterial Infection
    Maleic Acid (Standard) is the analytical standard of Maleic Acid. This product is intended for research and analytical applications. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. IC50 & Target: GAD . In Vitro: The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal .
    Maleic Acid (Standard)

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