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Results for "

Glycyrrhiza

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Aldose Reductase (3) Amyloid-β (2) Apoptosis (5) Autophagy (3) Bacterial (8) Beta-secretase (1) Caspase (1) CCR (1) COX (2) Cytochrome P450 (1) Endogenous Metabolite (4) Estrogen Receptor/ERR (1) Glucosidase (1) HIV (1) Influenza Virus (2) MMP (1) NF-κB (3) NOD-like Receptor (NLR) (2) p38 MAPK (1) Parasite (2) Phosphatase (3) PPAR (4) Reactive Oxygen Species (4)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Endocrinology (1) Infection (11) Inflammation/Immunology (21) Metabolic Disease (9) Neurological Disease (6)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N9919

Glyasperin C	Others	Others
Glyasperin C is a potent and reversible noncompetitive inhibitor of neuraminidase with an IC₅₀ of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis .

HY-N8656

Glycyrrhiza-flavonol A	Others	Others
Glycyrrhiza-flavonol A (compound 4) is a natural product of Glycyrrhiza, Fabaceae .

HY-N11026

22-Beta-Acetoxyglycyrrhizin	Others	Others
22-Beta-Acetoxyglycyrrhizin is a triterpene glucuronide that can be isolated from the roots of Glycyrrhiza .

HY-N7372

Licoisoflavanone	Others	Others
Licoisoflavanone is the isoflavonoid compound isolated from Sinkiang licorice root (Glycyrrhiza) .

HY-N11773

Gancaonin L	PPAR	Metabolic Disease
Gancaonin L is an isoflavone, that can be isolated from Glycyrrhiza glabra roots. Gancaonin L exhibits significant PPAR-γ ligand-binding activity. Gancaonin L can be used for anti-diabetes and anti-obesity research .

HY-N8610

Uralsaponin D	Phosphatase	Inflammation/Immunology
Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA₂) with an IC₅₀ value of 32.2 μM .

HY-N8609

Uralsaponin C	Others	Others
Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .

HY-N13021

2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid	Endogenous Metabolite	Others
2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid is a metabolite, which can be isolated from endophytic fungus Phoma macrostoma inhabiting the inner tissue of medicinal plant Glycyrrhiza glabra Linn .

HY-108421

Xinjiachalcone A	Bacterial	Infection
Xinjiachalcone A is an active principle of Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori, with MIC values ranged from 12.5 to 50 µM for seventeen H. pylori strains .

HY-N1230

Sophoraisoflavone A Allolicoisoflavone B	Phosphatase	Inflammation/Immunology
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC₅₀ value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation .

HY-N3920

Gancaonin G	Bacterial	Infection
Gancaonin G is a 6-prenylated isoflavanone that can be isolated from Glycyrrhiza uralensis. Gancaonin G has antibacterial activity against Streptococcus mutants and MRSA strains .

HY-154795

Magnesium isoglycyrrhizinate hydrate	Caspase NOD-like Receptor (NLR)	Inflammation/Immunology
Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant (Glycyrrhiza glabra). Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats .

HY-N0376

Liquiritin 5+ Cited Publications	Reactive Oxygen Species	Neurological Disease Inflammation/Immunology Cancer
Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC₅₀s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo . Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity .

HY-N6987

Licraside	Others	Inflammation/Immunology
Licraside is isolated from Glycyrrhiza uralesis Fish.

HY-N10144

Shinpterocarpin	Others	Others
Shinpterocarpin is a flavonoid that can be found in Glycyrrhiza glabra L. .

HY-N2122

Neoisoliquiritin Neoisoliquiritigenin	Others	Cancer
Neoisoliquiritin is a bioactive component isolated from Glycyrrhiza uralensis .

HY-N1093

(-)-Vestitol (3R)-Vestitol	Others	Others
(-)-Vestitol is a compound isolated from Glycyrrhiza pallidiflora (Leguminosae) .

HY-N2123

Neoliquiritin	Others	Inflammation/Immunology
Neoliquiritin is isolated from Glycyrrhiza uralensis with an anti-inflammatory activity .

HY-N6983

Licoricesaponin G2	Others	Cancer
Licoricesaponin G2 is a pentacyclic triterpenoid isolated from Glycyrrhiza aspera .

HY-142096

Glycyuralin E	Others	Others
Glycyuralin E is a natural product that can be isolated from Glycyrrhiza uralensis .

HY-N8813

Glucoliquiritin	Others	Others
Glucoliquiritin is a Flavonoids product that can be isolated from the roots of Glycyrrhiza glabra L. .

HY-N6981

Methyl Glycyrrhizate	Others	Metabolic Disease Cancer
Methyl Glycyrrhizate, derived from Glycyrrhiza uralensis Fisch., is the ester of methyl alcohol and Glycyrrhizic Acid .

HY-N6984

Glycyroside	Others	Metabolic Disease
Glycyroside is a isoflavone diglycoside isolated from Glycyrrhiza eurycarpa P. C. Li .

HY-N11771

Glyurallin B	Others	Others
Glyurallin B is a flavonoid, that can be isolated from licorice (Glycyrrhiza inflata and Glycyrrhiza uralensis). Glyurallin B shows ABTS ⁺ radical scavenging activity and the inhibitory activity on lipid peroxidation, with EC₅₀ values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectivley .

HY-N7231

Licoricesaponin E2	Others	Others
Licoricesaponin E2 (compound 5) is a triterpene saponinthat can be found in Glycyrrhiza inflata .

HY-N12289

Kanzonol D	Others	Others
Kanzonol D is a flavonoid compound that can be found in the hairy root cultures of Glycyrrhiza glabra .

HY-N3922

Gancaonin M	Others	Others
Gancaonin M is a Flavonoids product that can be isolated from the roots of Glycyrrhiza uralensis Fisch .

HY-N8613

Gancaonin N	Others	Others
Gancaonin N is a Flavonoids product that can be isolated from the roots of Glycyrrhiza aspera Pall. .

HY-N8925

Glyasperin F	Others	Others
Glyasperin F is a Flavonoids product that can be isolated from the roots of Glycyrrhiza aspera Pall. .

HY-N11115

Macedonoside A	Others	Others
Macedonoside A (compound 3) is a kind of saponin. Macedonoside A can be isolated from the stolons of Glycyrrhiza lepidota .

HY-N6975

Glyasperin D	Bacterial	Infection
Glyasperin D is a flavonoid isolated from Glycyrrhiza uralensis, and possesses weaker anti-Helicobacter pylori activity .

HY-N3385

Licorisoflavan A 7-O-Methyllicorisoflavan B	Others	Others
Licorisoflavan A (7-O-Methyllicorisoflavan B) is a isoflavan-quinone, that can be isolated from Glycyrrhiza uralensis .

HY-N11111

Glycyrrhizin-6'-methylester	Others	Others
Glycyrrhizin-6'-methylester is a natural product that can be isolated from licorice (Glycyrrhiza glabra) .

HY-N7804

4'-O-Methylcoumestrol	Others	Others
4'-O-Methylcoumestrol is a Coumarins product that can be isolated from the herbs of Glycyrrhiza pallidiflora Maxim. .

HY-N0180

18β-Glycyrrhetinic acid 5+ Cited Publications	Endogenous Metabolite	Inflammation/Immunology Cancer
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.

HY-N4186

Glabrolide	Beta-secretase	Neurological Disease
Glabrolide, derived from Glycyrrhiza uralensis Fisch., is a β-secretase 1 (BACE-1) inhibitor[1].

HY-N3947

Glepidotin B	Bacterial	Infection
Glepidotin B is a dihydroflavonol compound isolated from the extracts of American licorice, Glycyrrhiza lepidota (Leguminosae). Glepidotin B is an antimicrobial agent .

HY-N6583

Licoflavonol	Bacterial	Infection
Licoflavonol, a minor flavone from the roots of Glycyrrhiza uralensis, is an inhibitor of the Salmonella type III secretion system (T3SS) .

HY-N6911

Licorice-saponin H2 (18β,20α)-Glycyrrhizic acid	Others	Metabolic Disease
Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin from Glycyrrhiza uralensis Fischer .

HY-W049311

4-Methyl-5,6,7,8-tetrahydroquinoline	Others	Others
4-Methyl-5,6,7,8-tetrahydroquinoline, a tetrahydroquinoline alkaloid, is isolated from the roots of Glycyrrhiza uralensis Fisch .

HY-N2123R

Neoliquiritin (Standard)	Others	Inflammation/Immunology
Neoliquiritin (Standard) is the analytical standard of Neoliquiritin. This product is intended for research and analytical applications. Neoliquiritin is isolated from Glycyrrhiza uralensis with an anti-inflammatory activity .

HY-N4194

Glabrone	PPAR	Metabolic Disease
Glabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity .

HY-N0377

Liquiritigenin 5+ Cited Publications 4',7-Dihydroxyflavanone	Estrogen Receptor/ERR	Neurological Disease Inflammation/Immunology Cancer
Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC₅₀ of 36.5 nM for activation of the ERE tk-Luc.

HY-N4182

Licochalcone E	Akt p38 MAPK Autophagy	Inflammation/Immunology
Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation .

HY-N6989

Isoglycycoumarin	Cytochrome P450	Metabolic Disease
Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6) .

HY-N4185

Licoflavone A 1 Publications Verification	Phosphatase	Neurological Disease
Licoflavone A is a flavonoid isolated from the roots of Glycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC₅₀ of 54.5 μM .

HY-N0102

Isoliquiritigenin Maximum Cited Publications 18 Publications Verification GU17; ISL; Isoliquiritigen; SJ000286237	Aldose Reductase Influenza Virus Autophagy Apoptosis	Infection Inflammation/Immunology Cancer
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC₅₀ of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC₅₀ of 24.7 μM.

HY-N3961

Neoglycyrol	Others	Cardiovascular Disease
Neoglycyrol is isolated from the root of Glycyrrhiza uralensis Fisch . Neoglycyrol is a potential myocardial protection active compound screened from traditional patent medicine Tongmai Yangxin pill (TMYXP) .

HY-N4184

Licoflavone B	Parasite	Infection
Licoflavone B is a flavonoid isolated from Glycyrrhiza inflata, inhibits S. mansoni ATPase (IC₅₀, 23.78 µM) and ADPase (IC₅₀, 31.50 µM) activity. Anti-schistosomiasis activity .

HY-N8947

Glyurallin A	Endogenous Metabolite Glucosidase	Metabolic Disease
Glyurallin A (Compound 79) is isolated from the naturalGlycyrrhiza uralensis. Glyurallin A inhibitsα-Glucosidase(HY-P2802)(IC₅₀=0.3 μM). Glyurallin A can be used in the study of anti-diabetes .

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Glycyrrhiza

Inhibitors & Agonists

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Natural
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