Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside (Synonyms: Liquiritigenin-7-apiosylglucoside)

Name: Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside
Brand: MedChemExpress
SKU: HY-N6986
Rating: 4.5 (1 reviews)

Cat. No.: HY-N6986 Purity: 99.52%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

Help & FAQs

Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside (Liquiritigenin-7-apiosylglucoside) is a flavonoid isolated from the roots of Glycyrrhiza, has weaker cytotoxicity against several tumor cells and normal cells.

For research use only. We do not sell to patients.

Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside Chemical Structure

CAS No. : 135432-48-3

Size	Price	Stock	Quantity
1 mg	USD 150	In-stock	Estimated Time of Arrival: April 16
5 mg	USD 365	In-stock	Estimated Time of Arrival: April 16
10 mg	USD 580	In-stock	Estimated Time of Arrival: April 16
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Molecular Weight

550.51

Formula

C₂₆H₃₀O₁₃

CAS No.

135432-48-3

Appearance

Solid

Color

Light yellow to yellow

SMILES

O[C@H]([C@](CO)(O)CO1)[C@]1([H])O[C@H]2[C@@H](O[C@H](CO)[C@@H](O)[C@@H]2O)OC3=CC=C(C(C[C@@H](C4=CC=C(O)C=C4)O5)=O)C5=C3

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (181.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8165 mL	9.0825 mL	18.1650 mL
5 mM	0.3633 mL	1.8165 mL	3.6330 mL
10 mM	0.1816 mL	0.9082 mL	1.8165 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (4.54 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (4.54 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (4.54 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, PEG300/PEG400, Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Purity & Documentation

Purity: 99.52%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (249 KB) HNMR (263 KB) CNMR (264 KB) RP-HPLC (190 KB)

Handling Instructions (2659 KB)

References

[1]. Ohno H, et al. Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure. Anticancer Res. 2013 Aug;33(8):3061-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8165 mL	9.0825 mL	18.1650 mL	45.4124 mL
	5 mM	0.3633 mL	1.8165 mL	3.6330 mL	9.0825 mL
	10 mM	0.1816 mL	0.9082 mL	1.8165 mL	4.5412 mL
	15 mM	0.1211 mL	0.6055 mL	1.2110 mL	3.0275 mL
	20 mM	0.0908 mL	0.4541 mL	0.9082 mL	2.2706 mL
	25 mM	0.0727 mL	0.3633 mL	0.7266 mL	1.8165 mL
	30 mM	0.0605 mL	0.3027 mL	0.6055 mL	1.5137 mL
	40 mM	0.0454 mL	0.2271 mL	0.4541 mL	1.1353 mL
	50 mM	0.0363 mL	0.1816 mL	0.3633 mL	0.9082 mL
	60 mM	0.0303 mL	0.1514 mL	0.3027 mL	0.7569 mL
	80 mM	0.0227 mL	0.1135 mL	0.2271 mL	0.5677 mL
	100 mM	0.0182 mL	0.0908 mL	0.1816 mL	0.4541 mL

Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside Related Classifications

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?
1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss. 2. Taking 10 μg as an example, first add 20 μL of reconstituted solution provided by MCE and use a pipette to gently resuspend the lyophilized protein until it is fully dissolved.. (For most proteins, the reconstitution solution we provide is sterile water. If a diluent other than water is required, it will be indicated in the product's Certificate of Analysis (COA).). 3. Add an additional 80 μL of buffer/culture medium containing carrier protein (either 0.1% BSA, 5% HSA, 10% FBS, or 5% trehalose), and then use a pipette to gently mix until uniform. The final concentration is should not be lower than 100 μg/mL. 4. Aliquot at least 20 μL per tube. 5. After aliquoting, store it frozen at a temperature ranging from -20ºC to -80ºC, and it can be preserved for 3 to 6 months.
How should solution-form recombinant proteins be stored?
1. The product can be stored in its original form and diluted as needed upon use. 2. Alternatively, dilute with a buffer/culture medium containing a carrier protein (either 0.1% BSA, 5% HSA, 10% FBS, or 5% alginate), mix well by pipetting, and ensure that
Why is it necessary to add carrier proteins?
Carrier proteins are commonly added to enhance the stability of recombinant proteins, preventing them from adhering to the walls of the container during freezing or thawing processes. Plastic tubes have a certain adsorptive capacity for proteins, which may lead to difficulty in separating the protein from the tube walls, resulting in a decrease in the actual concentration of the protein in the solution and thus affecting its activity. To minimize such losses, it is recommended to add a commonly used carrier protein solution prior to the long-term storage of recombinant protein products.
Carrier protein types and options?
In cases where the carrier protein is not expected to influence the experimental outcomes, an appropriate carrier protein, such as 0.1% BSA (Bovine Serum Albumin), 5% HSA (Human Serum Albumin), 10% FBS (Fetal Bovine Serum), or 5% trehalose, can be incorpo

Keywords:

Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside135432-48-3Liquiritigenin-7-apiosylglucosideOthersInhibitorinhibitorinhibit

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Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside (Synonyms: Liquiritigenin-7-apiosylglucoside)

Customer Review

Featured Recommendations

•Related Screening Libraries:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Liquiritigenin-7-O-β-D-glucopyranosyl-(1→2)-β-D-apiofuranoside Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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SAFETY DATA SHEET (SDS)

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