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Results for "

Hypouricemic

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153968
    URAT1&XO inhibitor 1

    		Xanthine Oxidase URAT1 Metabolic Disease
    URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research .
    URAT1&XO inhibitor 1
  • HY-146297
    Xanthine oxidoreductase-IN-2

    		Xanthine Oxidase Metabolic Disease
    Xanthine oxidoreductase-IN-2 (Compound IVa) is a xanthine oxidoreductase (XOR) inhibitor with the IC50 of 7.2 nM. Xanthine oxidoreductase-IN-2 shows hypouricemic effects in mice .
    Xanthine oxidoreductase-IN-2
  • HY-144456
    Xanthine oxidase-IN-5

    		Xanthine Oxidase Metabolic Disease
    Xanthine oxidase-IN-5 is an effective and orally active xanthine oxidase (XO) inhibitor with IC50 value of 0.70 μM. Xanthine oxidase-IN-5 displays favorable agent-like properties with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 shows potent hypouricemic effects in hyperuricemic rat model .
    Xanthine oxidase-IN-5
  • HY-168740
    URAT1 inhibitor 11

    		URAT1 Metabolic Disease
    URAT1 inhibitor 11 (Compound 7) is a URAT1 inhibitor with an IC50 value of 0.18 μM. URAT1 inhibitor 11 exhibits potent hypouricemic effects in hyperuricemic zebrafish induced by Potassium oxonate (HY-17511) and Xanthine sodium salt (HY-W017389) .
    URAT1 inhibitor 11
  • HY-144303
    Xanthine oxidase-IN-4

    		Xanthine Oxidase Metabolic Disease
    Xanthine oxidase-IN-4 (compound 19a) is an orally active and potent xanthine oxidase (XO) inhibitor, with an IC50 of 0.039 μM. Xanthine oxidase-IN-4 exhibits hypouricemic potency in potassium oxonate induced hyperuricemia rats. Xanthine oxidase-IN-4 can be used for hyperuricemia and gout research .
    Xanthine oxidase-IN-4
  • HY-151974
    Xanthine oxidoreductase-IN-4

    		Xanthine Oxidase Metabolic Disease
    Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia .
    Xanthine oxidoreductase-IN-4
  • HY-162961
    Xanthine oxidase-IN-16

    		Xanthine Oxidase Metabolic Disease
    Xanthine oxidase-IN-16 is potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 102 nM. Xanthine oxidase-IN-16 shows significant efficacy in hyperuricemia rats .
    Xanthine oxidase-IN-16

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