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Results for "

MCT

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (2) Biochemical Assay Reagents (2) c-Met/HGFR (2) Cytochrome P450 (1) Endogenous Metabolite (4) Glutaminase (2) iGluR (2) Mitochondrial Metabolism (2) Monocarboxylate Transporter (19) P-glycoprotein (1) Small Interfering RNA (siRNA) (1) TGF-β Receptor (1) Tyrosinase (2)
By Research Areas:	Cancer (15) Cardiovascular Disease (3) Endocrinology (2) Inflammation/Immunology (4) Metabolic Disease (5) Neurological Disease (7)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

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Natural
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Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-150314

MCT-IN-1	Monocarboxylate Transporter	Cancer
MCT-IN-1 (compound 2) is a potent inhibitor of monocarboxylate transporter (MCT), with the IC₅₀ of 9 nM and 14 nM for *MCT1* and *MCT4*, respectively .

HY-18974

MCT1-IN-2	Monocarboxylate Transporter	Cancer
MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity .

HY-132301

MSC-4381 MCT4-IN-1	Monocarboxylate Transporter	Cancer
MSC-4381 (MCT4-IN-1) is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC₅₀ of 77 nM and a K_i of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research . MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N4115

Syrosingopine 5 Publications Verification Su 3118	Monocarboxylate Transporter	Cardiovascular Disease Cancer
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine .

HY-B1804

Tricaprilin Trioctanoin; Glyceryl trioctanoate	Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Tricaprilin (Trioctanoin) is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) .

HY-D0067

7ACC1 5+ Cited Publications DEAC; Coumarin D 1421; D 1421	Monocarboxylate Transporter	Cancer
7ACC1 (DEAC; Coumarin D 1421; D 1421) is a monocarboxylate transporter 1 (MCT-1)/MCT-4 specifc blocker. 7ACC1 attenuates renal cancer cell proliferation, migration, invasion and down-regulates the levels of *MCT1/MCT4* expression and extracellular lactate. 7ACC1 is promising for research of cancers .

HY-122312

BAY-8002 3 Publications Verification	Monocarboxylate Transporter	Cancer
BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC₅₀ of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity .

HY-148574

MCT1-IN-3	Monocarboxylate Transporter P-glycoprotein	Cancer
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor with an IC₅₀ value of 81.0 nM. MCT1-IN-3 has also significant inhibitivity against the multidrug transporter ABCB1. MCT1-IN-3 can be used for the research of cancer .

HY-RS08251

MCTS1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MCTS1 Human Pre-designed siRNA Set A contains three designed siRNAs for MCTS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCTS1 Human Pre-designed siRNA Set A MCTS1 Human Pre-designed siRNA Set A

HY-119996A

AR-C141990 hydrochloride	Monocarboxylate Transporter	Inflammation/Immunology
AR-C141990 hydrochloride is a potent lactate transporters (monocarboxylate transporters; MCTs) inhibitor with pK_i values of 7.6, 6.6 for MCT-1 and MCT-2, respectively . AR-C141990 hydrochloride has immunosuppressive properties and inhibits graft versus host response .

HY-12750

AZD3965 Maximum Cited Publications 45 Publications Verification	Monocarboxylate Transporter	Cancer
AZD3965 is a selective *MCT1* inhibitor with a K_i of 1.6 nM, showing 6-fold selectivity over MCT2.

HY-13248

AR-C155858 35+ Cited Publications	Monocarboxylate Transporter	Others
AR-C155858 is a selective monocarboxylate transporter *MCT1* and *MCT2* inhibitor with K_is of 2.3 nM and 10 nM, respectively.

HY-N3097

Pellitorine	Others	Cancer
Pellitorine is a compound isolated from the roots of Piper nigrum. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. Pellitorine has the potential for the research of cancer diseases .

HY-107641

α-Cyano-4-hydroxycinnamic acid 3 Publications Verification α-Cyano-4-hydroxycinnamate	Monocarboxylate Transporter	Metabolic Disease
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

HY-139665

VB124 1 Publications Verification	Monocarboxylate Transporter	Cardiovascular Disease
VB124 is an orally active, potent, and selective *MCT4* inhibitor. VB124 can specifically inhibit lactate efflux with IC₅₀s of 8.6 nM and 19 nM for lactate import and export in MDA-MB-231 cells, respectively. VB124 is highly selective for MCT4 over MCT1. VB124 can be used for the research of cardiac hypertrophy, heart failure, and metabolism .

HY-160107

AZ1422	Monocarboxylate Transporter	Neurological Disease
AZ1422 is a selective *MCT4* inhibitor that can be used in cancer research .

HY-N3097R

Pellitorine (Standard)	Others	Cancer
Pellitorine (Standard) is the analytical standard of Pellitorine. This product is intended for research and analytical applications. Pellitorine is a compound isolated from the roots of Piper nigrum. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. Pellitorine has the potential for the research of cancer diseases .

HY-121025

BUR1	TGF-β Receptor	Others
BUR1 is a BMP upregulator (EC₅₀: 98 nM) and activates BMPRII signalling. BUR1 induces BMP2 and PTGS2 expression. BUR1 reversed pulmonary arterial pressure in Monocrotaline (HY-N0750) induced rats .

HY-N0647

Silychristin 1 Publications Verification	Monocarboxylate Transporter	Endocrinology
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter *MCT8*, and elicits a strong inhibition of T3 uptake with an IC₅₀ of 110 nM .

HY-148517

AZD0095 1 Publications Verification	Monocarboxylate Transporter	Cancer
AZD0095 is a selective and orally active *MCT4* inhibitor (IC₅₀: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib (HY-10205) .

HY-119996

AR-C141990	Monocarboxylate Transporter Cytochrome P450	Inflammation/Immunology
AR-C141990 (Compound 30) is a potent blocker of the monocarboxylate transporter MCT1 with a K_i of 4.8 nM. AR-C141990 (Compound 30) inhibits CYP3A4 and CYP2C9 with IC₅₀ values of 16 μM .

HY-W013136

Triheptanoin UX007	Biochemical Assay Reagents	Neurological Disease
Triheptanoin (Propane-1,2,3-triyl triheptanoate) is a synthetic medium-chain triglyceride (MCT) consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin can be used for the research of inherited metabolic disorders .

HY-D0713

7ACC2 5+ Cited Publications	Monocarboxylate Transporter Mitochondrial Metabolism	Cancer
7ACC2 is a potent monocarboxylate transporter (MCT) inhibitor with an IC₅₀ of 11 nM for inhibition of [ ¹⁴C]-lactate influx. 7ACC2 is also a potent inhibitor of mitochondrial pyruvate transport. 7ACC2 is an anticancer agent through inhibition of lactate flux .

HY-N0647R

Silychristin (Standard)	Monocarboxylate Transporter	Endocrinology
Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .

HY-W013136R

Triheptanoin (Standard)	Biochemical Assay Reagents	Neurological Disease
Triheptanoin (Standard) is the analytical standard of Triheptanoin. This product is intended for research and analytical applications. Triheptanoin (Propane-1,2,3-triyl triheptanoate) is a synthetic medium-chain triglyceride (MCT) consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin can be used for the research of inherited metabolic disorders .

HY-138559

GW604714X	Mitochondrial Metabolism	Neurological Disease
GW604714X is a potent inhibitor of mitochondrial respiration supported by pyruvate but not other substrates. GW604714X is a highly specific mitochondrial pyruvate carrier (MPC) inhibitor with a K_i <0.1 nM. GW604714X also inhibits L-lactate transport by the plasma membrane monocarboxylate transporter (MCT1), but at concentrations more than 4 orders of magnitude greater than the MPC .

HY-114602

AR-C117977	Monocarboxylate Transporter	Inflammation/Immunology
AR-C117977 is a potent monocarboxylate transporter (MCT1) inhibitor. AR-C117977 prolongs the survival of skin and heart sllograft. AR-C117977 inhibits the development of transplant arteriosclerosis in aortic allografts partially, but was unable to inhibit alloantibody production after transplantation. AR-C117977 shows potent immunosuppressive properties in vivo effectively preventing acute but not chronic allograft rejection in the mouse .

HY-W015309

Decanoic acid 1 Publications Verification	iGluR Tyrosinase c-Met/HGFR Glutaminase Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy .

HY-N6660

Trisdecanoin Tricaprin; Glyceryl tridecanoate	Endogenous Metabolite Androgen Receptor	Cardiovascular Disease Metabolic Disease
Trisdecanoin (Tricaprin; Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA precursor) that can be hydrolyzed to decanoic acid. Trisdecanoin and its metabolite capric acid not only provide the body with a quick source of energy, but can also affect lipid metabolism. Trisdecanoin is a major component of medium chain triglycerides (MCT), which has preventive or inhibitory properties for abdominal aortic aneurysms (AAA), inhibition of cardiovascular disease, and anti-androgen (NSAA) and anti-hyperglycemic properties. Trisdecanoin can be used as an additive in food, medicine and cosmetics .

HY-W015309R

Decanoic acid (Standard)	iGluR Tyrosinase c-Met/HGFR Glutaminase	Neurological Disease Metabolic Disease Cancer
Decanoic acid (Standard) is the analytical standard of Decanoic acid. This product is intended for research and analytical applications. Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy .

HY-N6660R

Trisdecanoin (Standard)	Endogenous Metabolite Androgen Receptor	Metabolic Disease
Trisdecanoin (Standard) is the analytical standard of Trisdecanoin. This product is intended for research and analytical applications. Trisdecanoin (Tricaprin; Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA precursor) that can be hydrolyzed to decanoic acid. Trisdecanoin and its metabolite capric acid not only provide the body with a quick source of energy, but can also affect lipid metabolism. Trisdecanoin is a major component of medium chain triglycerides (MCT), which has preventive or inhibitory properties for abdominal aortic aneurysms (AAA), inhibition of cardiovascular disease, and anti-androgen (NSAA) and anti-hyperglycemic properties. Trisdecanoin can be used as an additive in food, medicine and cosmetics .

Cat. No.	Product Name	Target	Research Area

HY-P10561

CPK peptide	Peptides	Cancer
CPK peptide is a tumor-localizing peptide. CPK peptide specifically binds to the monocarboxylate transporter 1 (MCT1) receptor, which is overexpressed in many human colon cancer cell lines but not in normal cells. CPK peptide can be used in tumor diagnosis research .

Tricaprilin Trioctanoin; Glyceryl trioctanoate	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Tricaprilin (Trioctanoin) is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) .

Pellitorine	Alkaloids Classification of Application Fields Other Alkaloids Source classification Piperaceae Plants Disease Research Fields Piper nigrum Linn. Biological Pesticide Research Cancer Agricultural Research	Others
Pellitorine is a compound isolated from the roots of Piper nigrum. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. Pellitorine has the potential for the research of cancer diseases .

Silychristin 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Flavanonols Flavonoids Glycine soya Phenols Polyphenols Disease Research Fields Endocrinology	Monocarboxylate Transporter
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter *MCT8*, and elicits a strong inhibition of T3 uptake with an IC₅₀ of 110 nM .

Decanoic acid 1 Publications Verification	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Biological Pesticide Research Agricultural Research	iGluR Tyrosinase c-Met/HGFR Glutaminase Endogenous Metabolite
Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy .

Trisdecanoin Tricaprin; Glyceryl tridecanoate	Ketones, Aldehydes, Acids Source classification umbellularia californica Metabolic Disease Plants Lauraceae Disease Research Fields	Endogenous Metabolite Androgen Receptor
Trisdecanoin (Tricaprin; Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA precursor) that can be hydrolyzed to decanoic acid. Trisdecanoin and its metabolite capric acid not only provide the body with a quick source of energy, but can also affect lipid metabolism. Trisdecanoin is a major component of medium chain triglycerides (MCT), which has preventive or inhibitory properties for abdominal aortic aneurysms (AAA), inhibition of cardiovascular disease, and anti-androgen (NSAA) and anti-hyperglycemic properties. Trisdecanoin can be used as an additive in food, medicine and cosmetics .

Pellitorine (Standard)	Alkaloids Other Alkaloids Source classification Piperaceae Plants Piper nigrum Linn.	Others
Pellitorine (Standard) is the analytical standard of Pellitorine. This product is intended for research and analytical applications. Pellitorine is a compound isolated from the roots of Piper nigrum. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. Pellitorine has the potential for the research of cancer diseases .

Silychristin (Standard)	Flavanonols Structural Classification Flavonoids Glycine soya Source classification Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Monocarboxylate Transporter
Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .

Decanoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	iGluR Tyrosinase c-Met/HGFR Glutaminase
Decanoic acid (Standard) is the analytical standard of Decanoic acid. This product is intended for research and analytical applications. Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy .

Trisdecanoin (Standard)	Ketones, Aldehydes, Acids Source classification umbellularia californica Plants Lauraceae	Endogenous Metabolite Androgen Receptor
Trisdecanoin (Standard) is the analytical standard of Trisdecanoin. This product is intended for research and analytical applications. Trisdecanoin (Tricaprin; Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA precursor) that can be hydrolyzed to decanoic acid. Trisdecanoin and its metabolite capric acid not only provide the body with a quick source of energy, but can also affect lipid metabolism. Trisdecanoin is a major component of medium chain triglycerides (MCT), which has preventive or inhibitory properties for abdominal aortic aneurysms (AAA), inhibition of cardiovascular disease, and anti-androgen (NSAA) and anti-hyperglycemic properties. Trisdecanoin can be used as an additive in food, medicine and cosmetics .

Species:	Human (2) Staphylococcus aureus (1)
Tag:	His (3) MBP (1) Flag (1)
Source:	P. pastoris (1) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71828

	MCT/SACOL1244 Protein, S. aureus (P.pastoris, His) 1 Publications Verification fabD; SACOL1244Malonyl CoA-acyl carrier protein transacylase; MCT; EC 2.3.1.39	Staphylococcus aureus	P. pastoris
	MCT/SACOL1244 Protein intricately participates in lipid metabolism, specifically playing a vital role in fatty acid biosynthesis. MCT/SACOL1244 Protein, S. aureus (P.pastoris, His) is the recombinant Staphylococcus aureus-derived MCT/SACOL1244 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of MCT/SACOL1244 Protein, S. aureus (P.pastoris, His) is 308 a.a., with molecular weight of ~35.6 kDa.

HY-P703259

	SLC16A3 Protein, Human (Sf9, His) MCT3; MCT4	Human	Sf9 insect cells
	SLC16A3 Protein, Human (Sf9, His) is the recombinant human-derived SLC16A3, expressed by Sf9 insect cells , with His labeled tag. ,

HY-P702021

	SLC16A2 Protein, Human (Sf9, His, MBP, FLAG) SLC16A2; Monocarboxylate transporter 8; MCT 8; Monocarboxylate transporter 7; MCT 7; Solute carrier family 16 member 2; X-linked PEST-containing transporter	Human	Sf9 insect cells
	The SLC16A2 protein is a specific thyroid hormone transmembrane transporter that promotes bidirectional movement of thyroid hormone across cell membranes independent of pH or Na(+) gradients. SLC16A2 has a significant preference for substrates such as T3 and T4 and is a key mediator of thyroid hormone transport. SLC16A2 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC16A2 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC16A2 Protein, Human (Sf9, His, MBP, FLAG) is 538 a.a., .

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HY-P83499

	Monocarboxylic Acid Transporter 1 Antibody (YA3244) HHF7; MCT 1; MCT; Slc16a1	WB	Human
	Monocarboxylic Acid Transporter 1 Antibody (YA3244) is a biotin-conjugated non-conjugated IgG antibody, targeting Monocarboxylic Acid Transporter 1, with a predicted molecular weight of 54 kDa (observed band size: 54 kDa). Monocarboxylic Acid Transporter 1 Antibody (YA3244) can be used for WB experiment in human background.

HY-P81884

	Mast Cell Chymase Antibody (YA1629) Chymase 1; Chymase; CMA1; CYH; CYM; Mcp-5; MCP3P; Mcpt5; MCT1; MMCP-5	WB, IHC-P	Human
	Mast Cell Chymase Antibody (YA1629) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1629), targeting Mast Cell Chymase, with a predicted molecular weight of 27 kDa (observed band size: 27 kDa). Mast Cell Chymase Antibody (YA1629) can be used for WB, IHC-P experiment in human background.

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