Mucin MUC1

By Targets:	Mucin (5) Endogenous Metabolite (1) Transmembrane Glycoprotein (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (6)
Oligonucleotides:	Aptamers (2)

Targets Recommended: Mucin Tim3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2508

MUC1, mucin core	Mucin	Cancer
MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1 .

HY-160060

MA3 aptamer sodium	Mucin	Cancer
MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium binds to the peptide epitope of mucin 1 (MUC1) with a Kd of 38.3 nM and has minimal cross-reactivity with albumin .

HY-P99968

Clivatuzumab	Mucin	Cancer
Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers .

HY-P99634

Gatipotuzumab PankoMab	Mucin	Cancer
Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) .

HY-E70290

N-Acetylgalactosaminyltransferase 1 GALNT1	Endogenous Metabolite β-catenin Wnt	Cancer
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer can promote abnormal O-glycosylation of CD44, thereby activating the Wnt/β-catenin signaling pathway and regulating the malignant behavior of gastric cancer cells. Additionally, N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying the O-glycosylation of various glycoproteins, such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3 .

HY-P5472

Tumour-associated MUC1 epitope	Transmembrane Glycoprotein	Others
Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.)

HY-160062

S2.2 aptamer sodium	Mucin	Cancer
S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM .

Cat. No.	Product Name	Target	Research Area

HY-P2508

MUC1, mucin core	Mucin	Cancer
MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1 .

HY-P5472

Tumour-associated MUC1 epitope	Transmembrane Glycoprotein	Others
Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.)

Cat. No.	Product Name	Target	Research Area

HY-P99968

Clivatuzumab	Mucin	Cancer
Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers .

HY-P99634

Gatipotuzumab PankoMab	Mucin	Cancer
Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) .

Species:	Human (9)
Tag:	His (3) Tag Free (1) Avi (2) Fc (5)
Source:	HEK293 (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P78774

	Mucin-1/MUC1 Protein, Human (HEK293, mFc) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293, mFc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P78833

	Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, His-Avi) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78733

	Mucin-1/MUC1 Protein, Human (269a.a, HEK293, His) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (269a.a, HEK293, His) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78734

	Mucin-1/MUC1 Protein, Human (120a.a, HEK293, His) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (120a.a, HEK293, His) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78740

	Mucin-1/MUC1 Protein, Human (357a.a, HEK293, Fc) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (357a.a, HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Mucin-1/MUC1 Protein, Human (357a.a, HEK293, Fc) is 357 a.a., with molecular weight of ~70 kDa.

HY-P70301

	Mucin-1/MUC1 Protein, Human (HEK293, Fc) rHuMUCin-1, Fc; MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated MUCin; CD227; MUC1	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Mucin-1/MUC1 Protein, Human (HEK293, Fc) is 145 a.a., with molecular weight of 45-88 kDa.

HY-P700795

	Mucin-1/MUC1 Isoform Y Protein, Human (HEK293, Fc) MUC1/Y; MUC1; MUC-1; MUCin-1; MUCin1; CA 15-3; Episialin; H23AG; KL-6; PEMT; PUM; PEM; EMA; CD227	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Isoform Y Protein, Human (HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 Isoform Y protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Mucin-1/MUC1 Isoform Y Protein, Human (HEK293, Fc) is 135 a.a., with molecular weight of 55-65 kDa.

HY-P73802

	Mucin-1/MUC1 Protein, Human (HEK293) MUCin-1; MUC-1; Episialin; CD227; MUC1-alpha	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with tag free. The total length of Mucin-1/MUC1 Protein, Human (HEK293) is 135 a.a., with molecular weight of ~15.4 kDa.

HY-P72399

	Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) MUC-1; CA 15-3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; PUM; PEM; EMA; CD227; MUC1	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 144 a.a., with molecular weight of 55-75 kDa.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83341

	Mucin 1 Antibody (YA3086) MUC1; PUM; MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated ep	WB, IHC-P, ICC/IF, IP, FC	Human
	Mucin 1 Antibody (YA3086) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3086), targeting Mucin 1, with a predicted molecular weight of 122 kDa (observed band size: 18-25 kDa). Mucin 1 Antibody (YA3086) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.

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Cat. No.	Product Name		Classification

HY-160060

MA3 aptamer sodium		Aptamers
MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium binds to the peptide epitope of mucin 1 (MUC1) with a Kd of 38.3 nM and has minimal cross-reactivity with albumin .

HY-160062

S2.2 aptamer sodium		Aptamers
S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM .

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