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Results for "

N3-PEG11-CH2CH2COOH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Notch (1) Opioid Receptor (1) PD-1/PD-L1 (1) PROTAC Linkers (1) β-catenin (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (1) Neurological Disease (1)
Click Chemistry:	PROTAC Synthesis (1) Azide (1)

5

Inhibitors & Agonists

7

Peptides

1

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

N-terminally acetylated Leu-enkephalin Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH	Opioid Receptor	Neurological Disease
N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

Notch 1 TFA	Notch	Cardiovascular Disease Cancer
Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types .

HY-P10392AF

fStAx-35R TFA	β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

BMS-986189	PD-1/PD-L1	Inflammation/Immunology Cancer
BMS-986189 is a macrocyclic peptide inhibitor of PD-L1 (IC₅₀: 1.03 nM), and can be used for cancer research .

Azido-PEG11-acid N3-PEG11-CH2CH2COOH	PROTAC Linkers	Cancer
Azido-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG11-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name	Target	Research Area

N-terminally acetylated Leu-enkephalin Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH	Opioid Receptor	Neurological Disease
N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

Notch 1 TFA	Notch	Cardiovascular Disease Cancer
Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types .

G7-18NATE TFA	Peptides	Cancer
G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (K_d = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .

HY-P10392AF

fStAx-35R TFA	β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

BMS-986189	PD-1/PD-L1	Inflammation/Immunology Cancer
BMS-986189 is a macrocyclic peptide inhibitor of PD-L1 (IC₅₀: 1.03 nM), and can be used for cancer research .

G7-18NATE	Peptides	Cancer
G7-18NATE is a peptide inhibitor of Grb7. HY-P10224 binds to the Grb7-SH2 domain with micromolar affinity (K_D = 18.1 μM). G7-18NATE inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines .

RP 71955	Peptides	Infection
RP 71955 is an antimicrobial peptide against HIV-1 .

Cat. No.	Product Name		Classification

Azido-PEG11-acid N3-PEG11-CH2CH2COOH		PROTAC Synthesis Azide
Azido-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG11-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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