Search Result
Results for "
Nitroimidazoles
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-136436
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- HY-W008216
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Hydroxy Dimetridazole
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Drug Metabolite
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Others
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HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
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- HY-136440
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Metronidazole-OH
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Bacterial
Parasite
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Infection
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Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-119900
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Parasite
Antibiotic
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Infection
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Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .
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- HY-119900R
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Parasite
Antibiotic
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Infection
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Carnidazole (Standard) is the analytical standard of Carnidazole. This product is intended for research and analytical applications. Carnidazole is an antiprotozoal agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .
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- HY-136436R
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Endogenous Metabolite
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Others
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Ternidazole (hydrochloride) (Standard) is the analytical standard of Ternidazole (hydrochloride). This product is intended for research and analytical applications. Ternidazole hydrochloride is a hydroxymetabolite of nitroimidazole, has antiprotozoic properties .
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- HY-W008216S
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Hydroxy Dimetridazole-d3
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Drug Metabolite
Isotope-Labeled Compounds
|
Infection
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HMMNI-d3 is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].
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- HY-W008216R
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Drug Metabolite
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Others
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HMMNI (Standard) is the analytical standard of HMMNI. This product is intended for research and analytical applications. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .
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- HY-136440S1
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Metronidazole-OH-d2
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Isotope-Labeled Compounds
|
Infection
|
Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-136440R
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Bacterial
Parasite
|
Infection
|
Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-13801
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HOE 239
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Parasite
|
Infection
|
Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei .
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- HY-78644R
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Biochemical Assay Reagents
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Others
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4-Nitroimidazole (Standard) is the analytical standard of 4-Nitroimidazole. This product is intended for research and analytical applications. 4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-13801R
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Parasite
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Infection
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Fexinidazole (Standard) is the analytical standard of Fexinidazole. This product is intended for research and analytical applications. Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei .
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- HY-B1244
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1,2-Dimethyl-5-nitroimidazole
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Parasite
Antibiotic
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Infection
|
Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections .
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- HY-W094047R
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|
Biochemical Assay Reagents
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Others
|
5-Chloro-1-methyl-4-nitroimidazole (Standard) is the analytical standard of 5-Chloro-1-methyl-4-nitroimidazole. This product is intended for research and analytical applications. 5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B0992
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- HY-123019
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-
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- HY-B1244R
-
|
Parasite
Antibiotic
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Infection
|
Dimetridazole (Standard) is the analytical standard of Dimetridazole. This product is intended for research and analytical applications. Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections .
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- HY-B0508
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-
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- HY-B0177
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-
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- HY-U00118
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-
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- HY-N0195
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2-Nitroimidazole
|
Bacterial
Antibiotic
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Infection
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Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
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- HY-116972
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SR 2508
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Biochemical Assay Reagents
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Cancer
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Etanidazole (SR 2508), a 2-nitroimidazole compound, is a hypoxic radiosensitizer used in cancer diagnosis and chemotherapy research .
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- HY-78644
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Biochemical Assay Reagents
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Others
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4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-107030
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- HY-18715
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(S)-Ornidazole; Levornidazole
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Bacterial
Parasite
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Infection
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Ornidazole Levo- is the levo-isomer of Ornidazole. Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Ornidazole Levo- is the less active isomer.
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- HY-B0177S
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Bacterial
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Infection
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Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa[1].
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- HY-W094047
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Biochemical Assay Reagents
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Others
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5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-121648
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Biochemical Assay Reagents
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Cancer
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PK 130 is a 2-nitroimidazole derivative that has radiosensitizing effects on hypoxic cells. PK 130 increases the radiosensitivity of Chinese hamster V79 cells under hypoxic conditions .
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- HY-B0177R
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Bacterial
Antibiotic
Parasite
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Infection
Cancer
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Tinidazole (Standard) is the analytical standard of Tinidazole. This product is intended for research and analytical applications. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa .
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- HY-121657
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Ro 11-2616
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Parasite
Bacterial
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Others
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Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
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- HY-16349
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K-1900
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Parasite
Antibiotic
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Infection
Cancer
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Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .
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- HY-B0508S1
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- HY-10845
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Bacterial
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Others
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CGI-17341 is a 5-nitroimidazole antibacterial agent that has the activity of inhibiting sensitive and multidrug-resistant strains of Mycobacterium tuberculosis in vitro and prolonging the survival time of mice infected with Mycobacterium tuberculosis in vivo in a dose-dependent manner.
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- HY-15781
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Bacterial
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Infection
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Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
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- HY-15781A
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Bacterial
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Infection
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(R)-Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. (R)-Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
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- HY-16349R
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Parasite
Antibiotic
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Infection
Cancer
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Nimorazole (Standard) is the analytical standard of Nimorazole. This product is intended for research and analytical applications. Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .
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- HY-121657R
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Parasite
Bacterial
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Others
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Ornidazole diol (Standard) is an analytical standard for Ornidazole diol. This product is used for research and analytical applications. Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
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- HY-136436S
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Endogenous Metabolite
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Others
|
Ternidazole-d6 (hydrochloride) is the deuterium labeled Ternidazole hydrochloride. Ternidazole hydrochloride is a hydroxymetabolite of nitroimidazole, has antiprotozoic properties[1][2].
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- HY-B1244S
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1,2-Dimethyl-5-nitroimidazole-d3
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Parasite
Antibiotic
|
Infection
|
Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
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- HY-B0318S1
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-
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- HY-135212
-
|
Endogenous Metabolite
|
Metabolic Disease
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Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-B0318
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-
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- HY-115249
-
|
Bacterial
Parasite
Antibiotic
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Infection
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Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
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- HY-P4561
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Cathepsin
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Others
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H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
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- HY-B0318S
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Bacterial
Parasite
Apoptosis
Antibiotic
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Infection
|
Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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- HY-P4556
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Biochemical Assay Reagents
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Others
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H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
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- HY-P4545
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Angiotensin Receptor
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Others
|
Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
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- HY-135212S
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Endogenous Metabolite
|
Metabolic Disease
|
Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].
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- HY-163545
-
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Drug Derivative
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Cancer
|
Tc-Me2P is a 99MTC-labeled acrylamide (PnAO) derivative that contains two 4-methyl-2-nitroimidazole groups. The primary activity of Tc-Me2P is as an imaging agent for tumor hypoxia. By specifically binding to hypoxic regions in tumor tissue, it can be used for single photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging to detect hypoxia in tumors. Tc-Me2P can be used to study the targeting of different chemical structures in tumors and normal tissues .
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- HY-163925
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Radionuclide-Drug Conjugates (RDCs)
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Cancer
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Lu-AAZTA-NI-PSMA-093 enhances tumor uptake and retention by combining a hypoxia-sensitive nitroimidazole (NI) moiety with a targeting moiety to PSMA. Lu-AAZTA-NI-PSMA-093 can be used in prostate cancer .
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- HY-136440S
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Metronidazole-OH-d4
|
Isotope-Labeled Compounds
Bacterial
Parasite
|
Infection
|
Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
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- HY-B0318A
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- HY-B0318R
-
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Bacterial
Parasite
Apoptosis
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
Metronidazole (Standard) is the analytical standard of Metronidazole. This product is intended for research and analytical applications. Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
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- HY-135212R
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .
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- HY-138094
-
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Drug Metabolite
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Infection
|
N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
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- HY-P4725
-
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Fluorescent Dye
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Others
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Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
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- HY-115249R
-
|
Parasite
Antibiotic
Bacterial
|
Infection
|
Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
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- HY-131257R
-
|
Drug Metabolite
|
Others
Cancer
|
Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
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- HY-122288
-
|
Bacterial
|
Infection
|
SC 28538 is a compound with antimicrobial activity. SC 28538 exerts its antimicrobial effect by reducing its nitro moiety in an anaerobic environment to form cytotoxic free radicals that can damage DNA and other key biomolecules of microorganisms .
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- HY-162074
-
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HIV
|
Infection
|
Nipamovir is a nitroimidazole prodrug. Nipamovir shows comparable antiviral activity to SAMT-247 (HY-102077) and NS-1040 in both cellular assays and a human ex vivo model of HIV infection, along with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively .
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- HY-119480
-
|
Bacterial
|
Infection
|
Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
|
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- HY-170779
-
|
FAP
|
Cancer
|
DOTA-NI-FAPI-04 is a FAP inhibitor (IC50 = 7.44 nM). By integrating FAP targeting with hypoxia-sensitive groups (nitroimidazole), DOTA-NI-FAPI-04 significantly enhances tumor uptake and retention capabilities. DOTA-NI-FAPI-04 chelates metallic isotopes (such as 68Ga and 177Lu) through DOTA to produce radioactive probes ([ 68Ga]Ga/DOTA-NI-FAPI-04 and [ 177Lu]Lu/DOTA-NI-FAPI-04), which can be used for research in tumor diagnostics and therapeutic agents. DOTA-NI-FAPI-04 holds dual targeting potential in the fields of cancer imaging, tumor microenvironment analysis, and radionuclide therapy, particularly suitable for scenarios where the tumor stroma and hypoxic regions synergistically interact .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-78644
-
|
Biochemical Assay Reagents
|
4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-78644R
-
|
Biochemical Assay Reagents
|
4-Nitroimidazole (Standard) is the analytical standard of 4-Nitroimidazole. This product is intended for research and analytical applications. 4-Nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W094047R
-
|
Biochemical Assay Reagents
|
5-Chloro-1-methyl-4-nitroimidazole (Standard) is the analytical standard of 5-Chloro-1-methyl-4-nitroimidazole. This product is intended for research and analytical applications. 5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W094047
-
|
Biochemical Assay Reagents
|
5-Chloro-1-methyl-4-nitroimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4545
-
|
Angiotensin Receptor
|
Others
|
Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
|
-
- HY-P4725
-
|
Fluorescent Dye
|
Others
|
Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
|
-
- HY-P4561
-
|
Cathepsin
|
Others
|
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
|
-
- HY-P4556
-
|
Biochemical Assay Reagents
|
Others
|
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B1244S
-
1 Publications Verification
|
Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
|
-
-
- HY-B0318S1
-
|
Metronidazole-d4 is the deuterium labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
|
-
-
- HY-B0318S
-
1 Publications Verification
|
Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
|
-
-
- HY-W008216S
-
|
HMMNI-d3 is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].
|
-
-
- HY-136440S1
-
|
Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
|
-
-
- HY-B0177S
-
|
Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa[1].
|
-
-
- HY-B0508S1
-
|
Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
|
-
-
- HY-136436S
-
|
Ternidazole-d6 (hydrochloride) is the deuterium labeled Ternidazole hydrochloride. Ternidazole hydrochloride is a hydroxymetabolite of nitroimidazole, has antiprotozoic properties[1][2].
|
-
-
- HY-135212S
-
|
Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].
|
-
-
- HY-136440S
-
|
Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
|
-
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