PE 22-28

By Targets:	Apoptosis (1) Biochemical Assay Reagents (1) Fluorescent Dye (1) HDAC (1) Potassium Channel (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (1) Neurological Disease (1)

Targets Recommended: CD28 CD22 URAT1 Oct3/4

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3581

PE 22-28	Potassium Channel	Neurological Disease
PE 22-28 is a TREK-1 inhibitor with IC₅₀ value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .

HY-B2228

Proteinase, Aspergillus oryzae	Biochemical Assay Reagents	Cancer
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

HY-N2228

(-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-EGCG-3''-O-ME	Others	Inflammation/Immunology Cancer
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product that can be isolated from the tea leaf, with strong antioxidative activity. (-)-Epigallocatechin-3-(3''-O-methyl) gallate has a strong cytotoxic activity for rat cancer cells .

HY-D2228

IR-7	Fluorescent Dye	Cancer
IR-7 is a mitochondria-targeted heptamethylindocyanine dye, and can used for cancer study.

HY-P2228

Chlamydocin	HDAC Apoptosis	Cancer
Chlamydocin, a fungal metabolite, is a highly potent HDAC inhibitor, with an IC₅₀ of 1.3 nM. Chlamydocin exhibits potent antiproliferative and anticancer activities. Chlamydocin induces apoptosis by activating caspase-3 .

Cat. No.	Product Name	Type

HY-D2228

IR-7	Fluorescent Dyes/Probes
IR-7 is a mitochondria-targeted heptamethylindocyanine dye, and can used for cancer study.

Cat. No.	Product Name	Type

HY-B2228

Proteinase, Aspergillus oryzae	Biochemical Assay Reagents
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

Proteinase, Aspergillus oryzae

Biochemical Assay Reagents

Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

Cat. No.	Product Name	Target	Research Area

HY-P3581

PE 22-28	Potassium Channel	Neurological Disease
PE 22-28 is a TREK-1 inhibitor with IC₅₀ value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .

HY-P2228

Chlamydocin	HDAC Apoptosis	Cancer
Chlamydocin, a fungal metabolite, is a highly potent HDAC inhibitor, with an IC₅₀ of 1.3 nM. Chlamydocin exhibits potent antiproliferative and anticancer activities. Chlamydocin induces apoptosis by activating caspase-3 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2228

(-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-EGCG-3''-O-ME	Structural Classification Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Disease Research Fields Theaceae Cancer	Others
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product that can be isolated from the tea leaf, with strong antioxidative activity. (-)-Epigallocatechin-3-(3''-O-methyl) gallate has a strong cytotoxic activity for rat cancer cells .

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Biochemical Assay Reagents

Peptides

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PE 22-28

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Natural
Products