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PEA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (3) ADC Linker (1) Amyloid-β (2) Bacterial (2) Cannabinoid Receptor (3) Ceramidase (3) Drug Intermediate (1) Endogenous Metabolite (7) FAAH (1) Fungal (1) GABA Receptor (2) Herbicide (2) Influenza Virus (1) Isotope-Labeled Compounds (4) NO Synthase (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (4) Endocrinology (3) Infection (3) Inflammation/Immunology (6) Metabolic Disease (6) Neurological Disease (7)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128929

Fmoc-PEA	ADC Linker	Cancer
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC) .

HY-147773

NAAA-IN-1	Ceramidase	Inflammation/Immunology
NAAA-IN-1 (Compound 1) is a potent and selective inhibitor of NAAA with an IC₅₀ of 7 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-1 has the potential for the research of inflammation and pain .

HY-P4886A

Amyloid β-Protein (3-42) TFA	Amyloid-β	Neurological Disease
Amyloid β-Protein (3-42) TFA is a precursor of Pyr peptide. Pyroglutamic acid-modified Aβ (pEAβ) (3-42) is the core of the amyloid plaque in Alzheimer's disease. pEAβ (3-42) accelerates the aggregation of Aβ(1-42), while Aβ(1-42) significantly slows down the primary and secondary nucleation of pEAβ(3-42).

HY-RS10309

PEA15 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PEA15 Human Pre-designed siRNA Set A contains three designed siRNAs for PEA15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PEA15 Human Pre-designed siRNA Set A PEA15 Human Pre-designed siRNA Set A

HY-157829

(R)-Palmitoyl-(2-methyl)ethanolamide Me-PEA	Endogenous Metabolite	Cancer
(R)-Palmitoyl-(2-methyl)ethanolamide (Me-PEA) is a competitive inhibitor of [3 H]-AEA metabolism with a K_i value of 6.6 μM .

HY-20685S2

Palmitoylethanolamide-d5 Palmidol-d₅, PEA-15,15,16,16,16-d₅	Isotope-Labeled Compounds Influenza Virus Endogenous Metabolite	Infection Cancer
Palmitoylethanolamide-d₅ (Palmidol-d₅, PEA-15,15,16,16,16-d₅) is deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract .

HY-147775

NAAA-IN-3	Ceramidase	Inflammation/Immunology
NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC₅₀ of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-3 has the potential for the research of inflammation and pain .

HY-P4886

Amyloid β-Protein (3-42)	Amyloid-β	Neurological Disease
Amyloid β-Protein (3-42) is the precursor of Pyr peptide. Pyroglutamate-modified Aβ (pEAβ) (3-42) is the core of the amyloid template block in Alzheimer's disease. pEAβ(3-42) accelerated the aggregation of Aβ(1-42), while Aβ(1-42) significantly slowed the primary and secondary nucleation of pEAβ(3-42) .

HY-W289164

Nonyl acetate	Endogenous Metabolite	Endocrinology
Nonyl acetate is a female pheromone isolated from pea moths (C. nigricana) .

HY-W780808

(E)-10-Dodecenol	Endogenous Metabolite	Endocrinology
(E)-10-Dodecenol is a sex pheromone capable of eliciting electroantennographic responses in male pea moths .

HY-W040194

Clomazone	Herbicide	Others
Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco .

HY-Y0989

Acetophenone 1 Publications Verification 1-Phenylethan-1-One	Drug Intermediate Fungal	Others
Acetophenone (1-Phenylethan-1-One) is an organic compound with simple structure. Acetophenone can be bioreduced to phenylethanol (PEA) .

HY-157833

Heptadecanoyl ethanolamide	Cannabinoid Receptor	Metabolic Disease
Heptadecanoyl ethanolamide is an endogenous cannabinoid. Heptadecanoyl ethanolamide is a synthetic analog of PEA which incorporates an odd-numbered (17-carbon) fatty acid chain .

HY-125407

Palmitoyl serinol N-Palmitoyl serinol	Cannabinoid Receptor	Inflammation/Immunology
Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin .

HY-120369

URB532	FAAH	Neurological Disease
URB532 is an inhibitor for fatty acid amide hydrolase (FAAH) with an IC₅₀ of 396 nM. URB532 increases levels of arachidonic acid acetamide (AEA), palmitoylethanolamide (PEA), and oleamide (OEA) in the rat brain, and exhibits anxiolytic and analgesic effects .

HY-W041333

Phenibut hydrochloride β-Phenyl-GABA hydrochloride; 4-Amino-3-phenylbutanoic acid hydrochloride; 4-Amino-3-phenylbutyric acid hydrochloride	GABA Receptor	Neurological Disease
Phenibut (β-Phenyl-GABA) hydrochloride is an orally active GABA-B agonist . Phenibut hydrochloride acts as a GABA-mimetic, primarily at GABAB?receptors. Phenibut hydrochloride has anxiolytic and nootropic (cognition enhancing) effects .

HY-108403

Phenibut β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid	GABA Receptor	Neurological Disease
Phenibut (β-Phenyl-GABA) is a GABA-B agonist . Phenibut acts as a GABA-mimetic, primarily at GABAB?receptors. Phenibut has anxiolytic and nootropic (cognition enhancing) effects .

HY-W040194R

Clomazone (Standard)	Herbicide	Others
Clomazone (Standard) is the analytical standard of Clomazone. This product is intended for research and analytical applications. Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco .

HY-120813

ARN 077 URB913	Ceramidase	Inflammation/Immunology
ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC₅₀ of 7 nM for human NAAA . ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats .

HY-112528

Glycerophospho-N-palmitoyl ethanolamine GP-NPEA	Endogenous Metabolite	Metabolic Disease
Glycerophospho-N-palmitoyl ethanolamine (GP-NPEA) is a metabolic precursor of palmitoyl ethanolamide PEA (HY-157829). Glycerophospho-N-palmitoyl ethanolamine decreases in the cortex of CUMS rats, which may be related to a disorder in the endocannabinoid system arising after the onset of depression .

HY-B1856

Haloxyfop	Acetyl-CoA Carboxylase	Metabolic Disease
Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC₅₀ of 0.5 μM, but has no effect on this enzyme in pea .

HY-125407S

Palmitoyl serinol-d5 N-Palmitoyl serinol-d₅	Cannabinoid Receptor	Inflammation/Immunology
Palmitoyl serinol-d₅ is the deuterium labeled Palmitoyl serinol[1]. Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin[2][3].

HY-B1856S

Haloxyfop-d4	Isotope-Labeled Compounds Acetyl-CoA Carboxylase	Metabolic Disease
Haloxyfop-d₄ is deuterium labeled Haloxyfop. Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC₅₀ of 0.5 μM, but has no effect on this enzyme in pea .

HY-B1856R

Haloxyfop (Standard)	Acetyl-CoA Carboxylase	Metabolic Disease
Haloxyfop (Standard) is the analytical standard of Haloxyfop. This product is intended for research and analytical applications. Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC50 of 0.5 μM, but has no effect on this enzyme in pea .

HY-P1028A

Hexa-D-arginine TFA 4 Publications Verification Furin Inhibitor II TFA	Bacterial	Infection
Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with K_i values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .

HY-P1028

Hexa-D-arginine 4 Publications Verification Furin Inhibitor II	Bacterial	Infection
Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with K_i values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .

HY-B0503

2-Thiouracil Thiouracil	NO Synthase	Endocrinology Cancer
2-Thiouracil (Thiouracil) is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a K_i value of 20 μM. 2-Thiouracil antagonizes BH4-induced nNOS dimerization. 2-Thiouracil is also an antithyroid compound and a highly specific melanoma detector. 2-Thiouracil stimulates the growth of pea and corn root segments .

HY-W007376

Indole-3-carboxaldehyde 1 Publications Verification 3-Formylindole	Endogenous Metabolite	Others
Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

HY-W007376S

Indole-3-carboxaldehyde-13C 3-Formylindole-¹³C₃	Isotope-Labeled Compounds Endogenous Metabolite	Others
Indole-3-carboxaldehyde- ¹³C (3-Formylindole- ¹³C) is a ¹³C labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin .

HY-W750674

Indole-3-carboxaldehyde-13C8 3-Formylindole-C¹³C₈	Isotope-Labeled Compounds	Inflammation/Immunology
Indole-3-carboxaldehyde- ¹³C₈ (3-Formylindole- ¹³C₈) is the ¹³C-labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde, a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

Cat. No.	Product Name	Target	Research Area

HY-P4886A

Amyloid β-Protein (3-42) TFA	Amyloid-β	Neurological Disease
Amyloid β-Protein (3-42) TFA is a precursor of Pyr peptide. Pyroglutamic acid-modified Aβ (pEAβ) (3-42) is the core of the amyloid plaque in Alzheimer's disease. pEAβ (3-42) accelerates the aggregation of Aβ(1-42), while Aβ(1-42) significantly slows down the primary and secondary nucleation of pEAβ(3-42).

HY-P1028A

Hexa-D-arginine TFA 4 Publications Verification Furin Inhibitor II TFA	Bacterial	Infection
Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with K_i values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .

HY-P1028

Hexa-D-arginine 4 Publications Verification Furin Inhibitor II	Bacterial	Infection
Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with K_i values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .

HY-P3636

Cockroach Myoactive Peptide I PEA-CAH-I	Peptides	Neurological Disease
Cockroach Myoactive Peptide I (Pea-CAH-I) is a cockroach neuropeptide, a member of the adipokinetic hormone/red pigment-concentrating hormone family (AKH/RPCH family) .

HY-P3635

Cockroach Myoactive Peptide II PEA-CAH-II	Peptides	Neurological Disease Metabolic Disease
Cockroach Myoactive Peptide II (Pea-CAH-II) is a cockroach neuropeptide. Cockroach Myoactive Peptide II is a member of the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family. Cockroach Myoactive Peptide II can be used for the research of metabolic functions of insect body .

HY-P4886

Amyloid β-Protein (3-42)	Amyloid-β	Neurological Disease
Amyloid β-Protein (3-42) is the precursor of Pyr peptide. Pyroglutamate-modified Aβ (pEAβ) (3-42) is the core of the amyloid template block in Alzheimer's disease. pEAβ(3-42) accelerated the aggregation of Aβ(1-42), while Aβ(1-42) significantly slowed the primary and secondary nucleation of pEAβ(3-42) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0989

Acetophenone 1 Publications Verification 1-Phenylethan-1-One	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Drug Intermediate Fungal
Acetophenone (1-Phenylethan-1-One) is an organic compound with simple structure. Acetophenone can be bioreduced to phenylethanol (PEA) .

HY-W007376

Indole-3-carboxaldehyde 1 Publications Verification 3-Formylindole	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Indole Alkaloids Alkaloids Human Gut Microbiota Metabolites Microorganisms Cruciferae Other Diseases Isatis tinctoria L. Disease Research Fields	Endogenous Metabolite
Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

HY-W289164

Nonyl acetate	Structural Classification Natural Products Animals Source classification	Endogenous Metabolite
Nonyl acetate is a female pheromone isolated from pea moths (C. nigricana) .

HY-W780808

(E)-10-Dodecenol	Structural Classification Natural Products Animals Source classification	Endogenous Metabolite
(E)-10-Dodecenol is a sex pheromone capable of eliciting electroantennographic responses in male pea moths .

Species:	Human (3)
Tag:	His (2) Tag Free (1) Strep (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P76767

	CBFB Protein, Human (His) Core-binding factor subunit beta; CBF-beta; PEA2-beta; PEBP2-beta	Human	E. coli
	CBFB forms a heterodimeric complex core binding factor (CBF) with RUNX family proteins, which enhances the DNA binding ability of RUNX members (such as RUNX1, RUNX2, and RUNX3). Heterodimers bind to specific sites in enhancers and promoters to regulate the transcription of target genes. CBFB Protein, Human (His) is the recombinant human-derived CBFB protein, expressed by E. coli , with N-6*His labeled tag. The total length of CBFB Protein, Human (His) is 181 a.a., with molecular weight of ~25 kDa.

HY-P71195

	PEA15 Protein, Human Astrocytic Phosphoprotein PEA-15; 15 kDa Phosphoprotein Enriched in Astrocytes; Phosphoprotein Enriched in Diabetes; PED; PEA15	Human	E. coli
	The PEA15 protein is a regulator of multiple cellular processes that blocks Ras-mediated integrin inhibition and modulates the ERK MAP kinase cascade. It inhibits RPS6KA3 activity by sequestering RPS6KA3 in the cytoplasm, regulating key cellular pathways. PEA15 Protein, Human is the recombinant human-derived PEA15 protein, expressed by E. coli , with tag free. The total length of PEA15 Protein, Human is 130 a.a., with molecular weight of 12-16 kDa.

HY-P703122

	ETV4 Protein, Human (His, Strep) E1AF; PEA3	Human	E. coli
	ETV4 Protein, Human (His, Strep) is the recombinant human-derived ETV4, expressed by E. coli , with Strep, His labeled tag. The total length of ETV4 Protein, Human (His, Strep) is 133 a.a.,

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Cat. No.	Product Name	Chemical Structure

HY-20685S2

Palmitoylethanolamide-d5
Palmitoylethanolamide-d₅ (Palmidol-d₅, PEA-15,15,16,16,16-d₅) is deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract .

HY-125407S

Palmitoyl serinol-d5
Palmitoyl serinol-d₅ is the deuterium labeled Palmitoyl serinol[1]. Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin[2][3].

HY-B1856S

Haloxyfop-d4
Haloxyfop-d₄ is deuterium labeled Haloxyfop. Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC₅₀ of 0.5 μM, but has no effect on this enzyme in pea .

HY-W007376S

Indole-3-carboxaldehyde-13C

Indole-3-carboxaldehyde- ¹³C (3-Formylindole- ¹³C) is a ¹³C labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin .

HY-W750674

Indole-3-carboxaldehyde-13C8

Indole-3-carboxaldehyde- ¹³C₈ (3-Formylindole- ¹³C₈) is the ¹³C-labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde, a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82261

	CBFB Antibody (YA2006) CBFB; Core-binding factor subunit beta; CBF-beta; Polyomavirus enhancer-binding protein 2 beta subunit; PEA2-beta; PEBP2-beta; SL3-3 enhancer factor 1 subunit beta; SL3/AKV core-binding factor beta subunit	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	CBFB Antibody (YA2006) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2006), targeting CBFB, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). CBFB Antibody (YA2006) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.