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Results for "

PRL-3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Phosphatase (4)
By Research Areas:	Cancer (4)

4

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

PRL-3 Inhibitor I	Phosphatase	Cancer
PRL-3 Inhibitor I is a potent *PRL-3* inhibitor with an IC₅₀ of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay .

PRL-3 Inhibitor 2	Phosphatase	Cancer
PRL-3 Inhibitor 2 (compound 2) is a potent *PRL-3* inhibitor with an IC₅₀ value of 28.1 µM .

Thienopyridone	Phosphatase Apoptosis	Cancer
Thienopyridone is a potent and selective *phosphatase of regenerating liver (PRL) phosphatase* inhibitor with IC₅₀s of 173 nM, 277 nM and 128 nM for *PRL-1, PRL-2, and PRL-3, respectively. Thienopyridone shows minimal effects on other phosphatases. Thienopyridone induces p130Cas cleavage and apoptosis* and has anticancer effects .

CG-707	Phosphatase	Cancer
CG-707 inhibits phosphatase of regenerating liver-3 (PRL-3) enzymatic activity with an IC₅₀ value of 0.8 μM. CG-707 inhibits the migration and invasion of *PRL-3* overexpressing colon cancer cells .

Species:	Human (3)
Tag:	His (2) Fc (1)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	SMR3B Protein, Human (HEK293, Fc) Submaxillary gland androgen-regulated protein 3B; PBII; PRL3; PROL3	Human	HEK293
	SMR3B Protein is an important oncogenic driver that promotes cancer progression and metastasis. SMR3B overexpression in multiple cancers has pleiotropic effects, causing cells to acquire hallmark traits such as sustained proliferative signaling, replicative immortality, genome instability and mutation, resistance to cell death, angiogenesis etc. In addition, up-regulation of SMR3B activates the Src kinase, which initiates a number of signal pathways culminating in the phosphorylation of ERK1/2, STAT3, and p130. SMR3B Protein, Human (HEK293, Fc) is the recombinant human-derived SMR3B protein, expressed by HEK293 , with C-mFc labeled tag. The total length of SMR3B Protein, Human (HEK293, Fc) is 79 a.a., with molecular weight of 35-40 kDa.

	SMR3B Protein, Human (HEK293, His) Submaxillary gland androgen-regulated protein 3B; PBII; PRL3; PROL3	Human	HEK293
	SMR3B Protein is an important oncogenic driver that promotes cancer progression and metastasis. SMR3B overexpression in multiple cancers has pleiotropic effects, causing cells to acquire hallmark traits such as sustained proliferative signaling, replicative immortality, genome instability and mutation, resistance to cell death, angiogenesis etc. In addition, up-regulation of SMR3B activates the Src kinase, which initiates a number of signal pathways culminating in the phosphorylation of ERK1/2, STAT3, and p130. SMR3B Protein, Human (HEK293, His) is the recombinant human-derived SMR3B protein, expressed by HEK293 , with C-His labeled tag. The total length of SMR3B Protein, Human (HEK293, His) is 79 a.a., with molecular weight of ~8 kDa.

	PTP4A3 Protein, Human (His) PRL-R; PRLR; PRL-3; PRL3; PTP4A3	Human	E. coli
	PTP4A3 Protein, a tyrosine phosphatase, accelerates cell cycle progression from G1 to S phase, fostering cell proliferation, motility, and invasion. Its role extends to promoting cancer metastasis, and it may contribute to cardiac hypertrophy progression by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 Protein, Human (His) is the recombinant human-derived PTP4A3 protein, expressed by E. coli , with N-His labeled tag. The total length of PTP4A3 Protein, Human (His) is 170 a.a., with molecular weight of 20.29 kDa.

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