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Results for "

PTS

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106031
    F-14512

    		Others Cancer
    F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC50=0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity .
    F-14512
  • HY-RS11455
    PTS Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PTS Human Pre-designed siRNA Set A contains three designed siRNAs for PTS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PTS Human Pre-designed siRNA Set A
    PTS Human Pre-designed siRNA Set A
  • HY-147062
    N-Acetyl-D-galactosamine-6-phosphate

    		Others Metabolic Disease
    N-acetyl-D-galactosamine 6-phosphate is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate can be hydrolyze by NagA .
    N-Acetyl-D-galactosamine-6-phosphate
  • HY-P10230
    Sublancin

    		Bacterial Infection
    Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM .
    Sublancin
  • HY-143456
    Anti-inflammatory agent 18

    		Others Inflammation/Immunology
    Anti-inflammatory agent 18 (compound 3b) shows NO inhibitory activity, with an IC50 of 15.94 μM. Anti-inflammatory agent 18 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 18 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .
    Anti-inflammatory agent 18
  • HY-143457
    Anti-inflammatory agent 19

    		Others Inflammation/Immunology
    Anti-inflammatory agent 19 (compound 2b) shows NO inhibitory activity, with an IC50 of 36.00 μM. Anti-inflammatory agent 19 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 19 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .
    Anti-inflammatory agent 19

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