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Results for "

Pyridoxal 5′-phosphate

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

5

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1

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1744
    Pyridoxal phosphate
    1 Publications Verification

    Pyridoxal 5′-phosphate; Pyridoxyl phosphate

    		 Reverse Transcriptase Endogenous Metabolite Neurological Disease
    Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
    Pyridoxal phosphate
  • HY-W011727
    Pyridoxal 5'-phosphate hydrate
    1 Publications Verification

    Pyridoxal phosphate hydrate

    		 Endogenous Metabolite Metabolic Disease
    Pyridoxal 5'-phosphate hydrate is an endogenous metabolite.
    Pyridoxal 5'-phosphate hydrate
  • HY-W011727A
    Pyridoxal 5'-​phosphate monohydrate
    1 Publications Verification

    Pyridoxal phosphate monohydrate

    		 Endogenous Metabolite Neurological Disease
    Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .
    Pyridoxal 5'-​phosphate monohydrate
  • HY-W011727S
    Pyridoxal Phosphate-d3

    Pyridoxal 5'-phosphate-d3

    		 Endogenous Metabolite Metabolic Disease
    Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate hydrate is an endogenous metabolite.
    Pyridoxal Phosphate-d3
  • HY-B1746
    Pyridoxamine 5′-phosphate

    		Endogenous Metabolite Neurological Disease
    Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .
    Pyridoxamine 5′-phosphate
  • HY-N2553
    4-Deoxypyridoxine 5'-phosphate

    		LPL Receptor Metabolic Disease
    4-Deoxypyridoxine 5'-phosphate is a Pyridoxal 5'-phosphate analogue and a sphingosine 1-phosphate (S1P) inhibitor. 4-Deoxypyridoxine 5'-phosphate inhibits ornithine decarboxylase activity with a Ki of 60 μM. 4-Deoxypyridoxine 5'-phosphate is a competitive inhibitor of the activation of glutamate apodecarboxylase by Pyridoxal 5'-phosphate (Ki of 0.27 μM) and strongly inhibits glutamate-dependent labeling of glutamate decarboxylase .
    4-Deoxypyridoxine 5'-phosphate
  • HY-P2825
    Tyrosine decarboxylase, Microorganism

    TDC; TyrDC

    		 Endogenous Metabolite Metabolic Disease Cancer
    Tyrosine decarboxylase, Microorganism (TDC) widely exists in plants, insects and different microorganisms, and is often used in biochemical research. Tyrosine decarboxylase is a pyridoxal 5'-phosphate (PLP)-dependent decarboxylase that catalyzes the removal of carboxyl groups from tyrosine to produce tyramine and carbon dioxide .
    Tyrosine decarboxylase, Microorganism
  • HY-162508
    KSK-104

    		Bacterial Infection
    KSK-104 has potent antibacterial activity against Mycobacterium tuberculosis (MIC=0.78 μM). The role of KSK-104 is mainly involved in the synthesis and recovery pathways of pyridoxal 5'-phosphate (PLP), PLP-dependent enzymes and oxidative stress networks. KSK-104, as a candidate molecule for novel anti-tuberculosis drugs, can be used to develop research against drug-resistant mycobacterium tuberculosis .
    KSK-104
  • HY-162652
    HSR-IN-1

    		Others Neurological Disease
    HSR-IN-1 (Compound 28) is an effective hSR (human serine racemase) inhibitor. In the presence of the cofactor Pyridoxal 5'-phosphate monohydrate (HY-W011727A), HSR-IN-1 has a Kd value of 5.4 μM and an IC50 of 18.3 μM for hSR, while the IC50 of HSR-IN-1 alone is 4.7 μM. HSR-IN-1 can be used for research on central nervous system diseases .
    HSR-IN-1

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