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Spore Germination

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (4) Bacterial (2) CXCR (2) Endogenous Metabolite (1) Fungal (13) Reactive Oxygen Species (1)
By Research Areas:	Infection (17) Inflammation/Immunology (2) Neurological Disease (2)

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Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0850

Difenoconazole	Fungal	Infection
Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .

HY-135549

Fluxapyroxad	Fungal Antibiotic	Infection
Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .

HY-B0850R

Difenoconazole (Standard)	Fungal	Infection
Difenoconazole (Standard) is the analytical standard of Difenoconazole. This product is intended for research and analytical applications. Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .

HY-W009274

N-Acetylmuramic acid MurNAc; NAMA	Endogenous Metabolite	Others
N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape .

HY-W012192

trans,trans-Dibenzylideneacetone (E,E)-Dibenzylideneacetone; trans,trans-Dibenzalacetone	Fungal	Infection
Dibenzylideneacetone (DBA) is a fruit antifungal agent with inhibitory activity against Botrytis cinerea Chitinase with an IC₅₀ of 13.10 μg/mL. Dibenzylideneacetone has an MIC of 32 μg/mL against B. cinerea and EC₅₀ values of 16.29 and 14.64 μg/mL in inhibiting mycelial growth and spore germination, respectively. Dibenzylideneacetone can overcomes Botrytis cinerea infection in cherry tomatoes by inhibiting chitinase activity .

HY-N9128

Medicarpin 3-O-glucoside	Others	Others
Medicarpin 3-O-glucoside a phytoalexin, shows inhibition against the germination of G. intraradices spores and hyphal elongation .

HY-N12976

Oryzalexin E	Fungal	Infection
Oryzalexin E is a diterpene phytoalexin, and can be isolated from UV-irradiated rice leaves. Oryzalexin E inhibits spore germination of Pyricularia oryzae with the ED₅₀ of 62.5 ppm .

HY-N13024

Radulone A	Fungal	Infection
Radulone A is a secondary metabolite, which can be isolated from the wood decomposing fungus Granulobasidium vellereum. Radulone A inhibits spore germination of Phlebiopsis gigantea, Coniophora puteana and Heterobasidion occidentale, with concentrations of 10 µM, 500 µM and 100 µM, respectively .

HY-143454

Germination-IN-1	Others	Inflammation/Immunology
Germination-IN-1 (compound 11) is a potent germination inhibitor with an IC₅₀ of 4 µM. Germination-IN-2 shows anti-germination activity with 14% germination rate .

HY-143455

Germination-IN-2	Others	Inflammation/Immunology
Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC₅₀ of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate .

HY-121387

Furmecyclox	Fungal	Infection
Furmecyclox is an effective fungicide. Furmecyclox shows great effects against basidiomycetes .

HY-75828

Dibenzylideneacetone Dibenzalacetone	Bacterial	Infection
Dibenzylideneacetone (Dibenzalacetone) is a potent inhibitor of chitinase with an IC₅₀ value of 13.10 μM. The MIC value of Dibenzylideneacetone against Botrytis cinerea is 32 μg/mL, and the EC₅₀ values for inhibiting mycelium growth and spore germination are 16.29 and 14.64 μg/mL, respectively. Dibenzylideneacetone can be used in research on fruit and vegetable preservatives .

HY-135549R

Fluxapyroxad (Standard)	Fungal Antibiotic	Infection
Fluxapyroxad (Standard) is the analytical standard of Fluxapyroxad. This product is intended for research and analytical applications. Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .

HY-N2573A

Corydalmine hydrochloride L-Corydalmine hydrochloride; TLZ-16-CL	Fungal CXCR	Infection Neurological Disease
Corydalmine hydrochloride inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine hydrochloride acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine hydrochloride alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .

HY-23155

2-Phenylethyl isothiocyanate 2-PE ITC	Fungal	Infection
2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity .

HY-N2573

Corydalmine L-Corydalmine; TLZ-16	Fungal CXCR	Infection Neurological Disease
Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .

HY-129548

Prumycin	Antibiotic	Infection
Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .

HY-129548A

Prumycin di(hydrochloride)	Others	Infection
Prumycin dihydrochloride is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin dihydrochloride significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin dihydrochloride did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .

HY-155004

SDH-IN-3	Antibiotic Fungal	Infection
SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 7.2 μg/mL. SDH-IN-3 exhibits excellent antifungal activities against Nigrospora oryzae with an EC₅₀ of 1.9 μg/mL. SDH-IN-3 can be used for anti-infection research .

HY-23155S

2-Phenylethyl isothiocyanate-d5 2-PE ITC-d₅	Fungal	Infection
2-Phenylethyl isothiocyanate-d₅ isothiocyanate-d₅ is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

HY-136409

N-Decanoyl-L-homoserine lactone C10-HSL	Bacterial Reactive Oxygen Species	Infection
N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca ²⁺ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .

Cat. No.	Product Name	Type

HY-W009274

N-Acetylmuramic acid MurNAc; NAMA	Enzyme Substrates
N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W009274

N-Acetylmuramic acid MurNAc; NAMA	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, essential for maintaining cell shape and integrity . N-acetylmuramic acid inhibits spore germination by inhibiting a coat-associated hexosaminidase and a core enzyme . N-acetylmuramic acid is required by Bacteroides forsythus for proliferation and the maintenance of its cell shape .

HY-136409

N-Decanoyl-L-homoserine lactone C10-HSL	Microorganisms Source classification	Bacterial Reactive Oxygen Species
N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca ²⁺ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .

HY-N9128

Medicarpin 3-O-glucoside	Structural Classification Natural Products Leguminosae Source classification Plants Trifolium pratense Linn.	Others
Medicarpin 3-O-glucoside a phytoalexin, shows inhibition against the germination of G. intraradices spores and hyphal elongation .

HY-N12976

Oryzalexin E	Structural Classification Natural Products Gramineae Source classification Oryza sativa L. Plants	Fungal
Oryzalexin E is a diterpene phytoalexin, and can be isolated from UV-irradiated rice leaves. Oryzalexin E inhibits spore germination of Pyricularia oryzae with the ED₅₀ of 62.5 ppm .

HY-N13024

Radulone A	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Fungal
Radulone A is a secondary metabolite, which can be isolated from the wood decomposing fungus Granulobasidium vellereum. Radulone A inhibits spore germination of Phlebiopsis gigantea, Coniophora puteana and Heterobasidion occidentale, with concentrations of 10 µM, 500 µM and 100 µM, respectively .

HY-N2573

Corydalmine L-Corydalmine; TLZ-16	Alkaloids Monophenols Corydalis yanhusuo W. T. Wang Source classification Phenols Plants Isoquinoline Alkaloids Papaveraceae	Fungal CXCR
Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .

Cat. No.	Product Name	Chemical Structure

HY-23155S

2-Phenylethyl isothiocyanate-d5
2-Phenylethyl isothiocyanate-d₅ isothiocyanate-d₅ is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

2-Phenylethyl isothiocyanate-d5

2-Phenylethyl isothiocyanate-d₅ isothiocyanate-d₅ is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

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Spore Germination

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products