Streptococcus mutans

By Targets:	Antibiotic (1) Apoptosis (1) Bacterial (11) Fungal (1) Parasite (1)
By Research Areas:	Cancer (1) Infection (11) Inflammation/Immunology (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2208A

Isobavachromene	Bacterial	Infection
Isobavachromene is an antibacterial agent .

HY-N2224

Guaijaverin	Bacterial	Infection
Guaijaverin is a urease inhibitor with an IC₅₀ of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .

HY-139338

Erlose	Others	Others
Erlose, a trisaccharide consisting of sucrose in soybean aphid honeydew, is utilized as a substitute sweetener preventing dental caries caused by oral flora, mainly Streptococcus mutans. Erlose may be used as a reference compound in HPLC assays that analyze the sugars of foods .

HY-N12240

Oleanolic aldehyde	Bacterial	Infection
Oleanolic aldehyde is an antimicrobial compound used to inhibit oral bacteria. Oleanolic aldehyde inhibits Streptococcus mutans and Porphyromonas gingivalis, which are associated with dental caries and periodontal disease, with minimum inhibitory concentrations (MICs) of 488 μg/mL and 250 μg/mL, respectively .

HY-NP023

Lactoferrin (human) CKRX; GIG12	Apoptosis Bacterial Fungal	Infection Cancer
Lactoferrin (human) is an iron-binding protein. Lactoferrin (human) has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin (human) can be used to culture mutans Streptococcus in iron-restricted medium .

HY-N12743

Farobin A	Bacterial	Infection Inflammation/Immunology
Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α .

HY-149330

HA5	Bacterial	Infection
HA5 inhibits Streptococcus mutans biofilm with an IC₅₀ value of 6.42 μM, without affecting its growth. HA5 also inhibits Streptococcus mutans glucan production and eDNA levels .

HY-P10696

C16G2	Bacterial Antibiotic	Infection
C16G2 is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutans. C16G2 specifically recognizes and disrupts the bacterial cell membrane, causing small molecule leakage and loss of membrane potential, leading to bacterial killing. Unlike broad-spectrum antimicrobial peptides, C16G2 exhibits higher selectivity and efficacy against Streptococcus mutans .

HY-W587957

Gypsogenic acid	Bacterial Parasite	Infection
Gypsogenic acid is a triterpenoid acid that can be isolated from Miconia stenostachya and has antibacterial and trypanoidal activities. The MICs values of Gypsogenic acid for the oral bacterial pathogens Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans and sobrinus were 50-200 μg/mL. Gypsogenic acid can induce blood cortensite cleavage in isolated mice with IC₅₀ 56.6 μM .

HY-N2224R

Guaijaverin (Standard)	Bacterial	Infection
Guaijaverin (Standard) is the analytical standard of Guaijaverin. This product is intended for research and analytical applications. Guaijaverin is a urease inhibitor with an IC₅₀ of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .

HY-P10362

Temporin-GHd	Bacterial	Infection
Temporin-GHd exhibits antibacterial activity against Streptococcus mutans (MIC=13.1 μM; MBC=26 μM). Temporin-GHd increases the permeability of the bacterial cell membrane, causing membrane damage and leakage of cellular contents. Temporin-GHd disrupts preformed biofilms at high concentrations. Temporin-GHd can bind to bacterial DNA, inhibiting DNA migration .

HY-149155

o-Cymen-5-ol	Bacterial	Infection
o-Cymen-5-ol is a broad-spectrum antimicrobial agent with direct antimicrobial activity. o-Cymen-5-ol showed effective minimum inhibitory concentrations (MICs) against a variety of bacteria and fungi, such as Streptococcus mutans and Candida albicans. The combination of o-Cymen-5-ol and zinc showed synergistic effects, enhancing the inhibitory effect against oral pathogens. o-Cymen-5-ol was able to inhibit the glycolysis process and co-enhanced this effect with zinc. o-Cymen-5-ol showed a stronger antibacterial effect in toothpaste than placebo .

Cat. No.	Product Name	Type

HY-NP023

Lactoferrin (human) CKRX; GIG12	Native Proteins
Lactoferrin (human) is an iron-binding protein. Lactoferrin (human) has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin (human) can be used to culture mutans Streptococcus in iron-restricted medium .

Cat. No.	Product Name	Target	Research Area

HY-P10696

C16G2	Bacterial Antibiotic	Infection
C16G2 is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutans. C16G2 specifically recognizes and disrupts the bacterial cell membrane, causing small molecule leakage and loss of membrane potential, leading to bacterial killing. Unlike broad-spectrum antimicrobial peptides, C16G2 exhibits higher selectivity and efficacy against Streptococcus mutans .

HY-P10362

Temporin-GHd	Bacterial	Infection
Temporin-GHd exhibits antibacterial activity against Streptococcus mutans (MIC=13.1 μM; MBC=26 μM). Temporin-GHd increases the permeability of the bacterial cell membrane, causing membrane damage and leakage of cellular contents. Temporin-GHd disrupts preformed biofilms at high concentrations. Temporin-GHd can bind to bacterial DNA, inhibiting DNA migration .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2208A

Isobavachromene	Infection Flavonoids Chalcones Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields	Bacterial
Isobavachromene is an antibacterial agent .

HY-N2224

Guaijaverin	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Rosaceae Phenols Polyphenols Plants Disease Research Fields Eriobotrya japonica (Thunb.) Lindl.	Bacterial
Guaijaverin is a urease inhibitor with an IC₅₀ of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .

HY-139338

Erlose	Polysaccharides Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields Sweeteners Saccharides Food Research	Others
Erlose, a trisaccharide consisting of sucrose in soybean aphid honeydew, is utilized as a substitute sweetener preventing dental caries caused by oral flora, mainly Streptococcus mutans. Erlose may be used as a reference compound in HPLC assays that analyze the sugars of foods .

HY-N12240

Oleanolic aldehyde	Triterpenes Structural Classification Terpenoids Source classification Vitis vinifera cv. Zalema Plants Vitaceae	Bacterial
Oleanolic aldehyde is an antimicrobial compound used to inhibit oral bacteria. Oleanolic aldehyde inhibits Streptococcus mutans and Porphyromonas gingivalis, which are associated with dental caries and periodontal disease, with minimum inhibitory concentrations (MICs) of 488 μg/mL and 250 μg/mL, respectively .

HY-N12743

Farobin A	Structural Classification Zea mays L. Flavonoids Flavones Gramineae Source classification Plants	Bacterial
Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α .

HY-N2224R

Guaijaverin (Standard)	Flavonols Structural Classification Flavonoids Source classification Rosaceae Phenols Polyphenols Plants Eriobotrya japonica (Thunb.) Lindl.	Bacterial
Guaijaverin (Standard) is the analytical standard of Guaijaverin. This product is intended for research and analytical applications. Guaijaverin is a urease inhibitor with an IC₅₀ of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .

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Streptococcus mutans

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