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Results for "

VPAC2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	GCGR (2) PACAP Receptor (3)
By Research Areas:	Inflammation/Immunology (1) Metabolic Disease (5) Neurological Disease (4)

5

Inhibitors & Agonists

6

Peptides

1

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Bay 55-9837	GCGR	Metabolic Disease
Bay 55-9837 is a potent and highly selective agonist of *VPAC2, with a K_d* of 0.65 nM. Bay 55-9837 may be a useful therapy for the research of type 2 diabetes .

PA-8	PACAP Receptor	Neurological Disease Inflammation/Immunology
PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC₅₀ of 2 nM ^[2].

PACAP (1-27), human, ovine, rat 2 Publications Verification PACAP 1-27	PACAP Receptor	Neurological Disease Metabolic Disease
PACAP (1-27), human, ovine, rat (PACAP 1-27) is the N-terminal fragment of PACAP-38, and is a potent PACAP receptor antagonist with IC₅₀s of 3 nM, 2 nM and 5 nM for rat PAC1, rat *VPAC1* and human *VPAC2*, respectively .

PACAP (1-27), human, ovine, rat TFA 2 Publications Verification PACAP 1-27 TFA	PACAP Receptor	Neurological Disease Metabolic Disease
PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is the N-terminal fragment of PACAP-38, and is a potent PACAP receptor antagonist with IC₅₀s of 3 nM, 2 nM and 5 nM for rat PAC1, rat *VPAC1* and human *VPAC2*, respectively .

Bay 55-9837 TFA	GCGR	Metabolic Disease
Bay 55-9837 TFA is a potent and highly selective agonist of *VPAC2, with a K_d* of 0.65 nM. Bay 55-9837 TFA may be a useful therapy for the research of type 2 diabetes .

Cat. No.	Product Name	Target	Research Area

Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr free acid	Peptides	Neurological Disease
Myristoyl-(Lys12,27,28)-VIP-Gly-Gly-Thr (free acid) is a high-affinity and selective VPAC2 receptor antagonist .

Bay 55-9837	GCGR	Metabolic Disease
Bay 55-9837 is a potent and highly selective agonist of *VPAC2, with a K_d* of 0.65 nM. Bay 55-9837 may be a useful therapy for the research of type 2 diabetes .

PACAP (1-27), human, ovine, rat 2 Publications Verification PACAP 1-27	PACAP Receptor	Neurological Disease Metabolic Disease
PACAP (1-27), human, ovine, rat (PACAP 1-27) is the N-terminal fragment of PACAP-38, and is a potent PACAP receptor antagonist with IC₅₀s of 3 nM, 2 nM and 5 nM for rat PAC1, rat *VPAC1* and human *VPAC2*, respectively .

PACAP (1-27), human, ovine, rat TFA 2 Publications Verification PACAP 1-27 TFA	PACAP Receptor	Neurological Disease Metabolic Disease
PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is the N-terminal fragment of PACAP-38, and is a potent PACAP receptor antagonist with IC₅₀s of 3 nM, 2 nM and 5 nM for rat PAC1, rat *VPAC1* and human *VPAC2*, respectively .

Bay 55-9837 TFA	GCGR	Metabolic Disease
Bay 55-9837 TFA is a potent and highly selective agonist of *VPAC2, with a K_d* of 0.65 nM. Bay 55-9837 TFA may be a useful therapy for the research of type 2 diabetes .

Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)	Peptides	Metabolic Disease
Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27), a vasoactive intestinal peptide (VIP), is a VIP₁ antagonist .

Cat. No.	Compare	Product Name	Species	Source

	VIPR2 Protein, Human (HEK293, Fc) Vasoactive intestinal polypeptide receptor 2; VIP-R-2; PACAP-R3; VPAC2; VIPR2	Human	HEK293
	VIPR2 protein, serving as a receptor for Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-Activating Peptide (PACAP-38 and -27), activates adenylyl cyclase and can also couple with phospholipase C. Its versatile signaling pathways emphasize its pivotal role in transducing signals from VIP and PACAP, participating in cellular processes regulated by cyclic AMP and phosphoinositide signaling cascades. VIPR2 Protein, Human (HEK293, Fc) is the recombinant human-derived VIPR2 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of VIPR2 Protein, Human (HEK293, Fc) is 103 a.a., with molecular weight of 45-60 kDa.

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	VPAC2 Antibody (YA1271) VIP2R; VIPR2; Vasoactive intestinal polypeptide receptor 2; VIP-R-2; Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor (PACAP type III receptor; PACAP-R-3; PACAP-R3); VPAC2	IHC-P	Human
	VPAC2 Antibody (YA1271) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1271), targeting VPAC2. VPAC2 Antibody (YA1271) can be used for IHC-P experiment in human background.

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