acetaldehyde

By Targets:	Aldehyde Dehydrogenase (ALDH) (5) Atg7 (1) Atg8/LC3 (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (2) Drug Derivative (1) Drug Intermediate (2) Endogenous Metabolite (7) Isotope-Labeled Compounds (2) Lipoxygenase (1) Na+/K+ ATPase (1) Prolyl Endopeptidase (PREP) (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Endocrinology (1) Inflammation/Immunology (2) Metabolic Disease (7) Neurological Disease (3)
Oligonucleotides:	Fillers (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141855S

Acetaldehyde 2,4-Dinitrophenylhydrazone-3,5,6-d3	Isotope-Labeled Compounds	Others
Acetaldehyde 2,4-Dinitrophenylhydrazone-3,5,6-d₃ is the deuterium labeled Acetaldehyde 2,4-Dinitrophenylhydrazone-3,5,6[1].

HY-100061A

*2-(Dimethylamino)acetaldehyde* hydrochloride**	Drug Intermediate	Others
2-(Dimethylamino)acetaldehyde hydrochloride can be used to synthesis Muscarine analogues .

HY-75884

2-(Triphenylphosphoranylidene)acetaldehyde	Biochemical Assay Reagents	Others
2-(Triphenylphosphoranylidene)acetaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B1429

Chlorpropamide 2 Publications Verification	Na+/K+ ATPase	Metabolic Disease Endocrinology
Chlorpropamide is an oral hypoglycemic agent that can influence acetaldehyde metabolism in mice and has a potentiating effect on antidiuretic hormone .

HY-P2796

Pyruvate decarboxylase PDC	Biochemical Assay Reagents	Metabolic Disease
Pyruvate decarboxylase (PDC) is an enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde. Pyruvate decarboxylase catalyses the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO₂ .

HY-W015969

1-Aminopropan-2-ol Monoisopropanolamine	Endogenous Metabolite	Metabolic Disease
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-100061

2-(Dimethylamino)acetaldehyde	Drug Intermediate	Others
2-(Dimethylamino)acetaldehyde can be used to synthesis Muscarine analogues .

HY-P2740B

Alcohol dehydrogenase, yeast	Endogenous Metabolite	Metabolic Disease
Alcohol dehydrogenase, yeast is an alcohol dehydrogenase expressed in yeast. It can catalyze the conversion between ethanol and acetaldehyde, while also reducing NAD or NADP, and it plays a role in glycolysis and aerobic respiration .

HY-133649

Dibromochloroacetaldehyde	Drug Derivative	Others
Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity .

HY-122373

Coprine	Aldehyde Dehydrogenase (ALDH)	Others
Coprine is a mycotoxin isolated from Coprinopsis atramentaria. Coprine is an acetaldehyde dehydrogenase inhibitor that causes the buildup of acetaldehyde, causing the alcohol flushing reaction .

HY-W004661

1,4-Dioxane-2,5-diol Hydroxy acetaldehyde	Endogenous Metabolite	Metabolic Disease
1,4-Dioxane-2,5-diol is an endogenous metabolite.

HY-N1177

Taraxerone	Aldehyde Dehydrogenase (ALDH)	Inflammation/Immunology
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC₅₀ values of 512.42 and 500.16 μM, respectively .

HY-P4308

Z-Pro-Pro-aldehyde-dimethyl acetal	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-126241

RV01	Aldehyde Dehydrogenase (ALDH)	Inflammation/Immunology
RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .

HY-W015969R

1-Aminopropan-2-ol (Standard)	Endogenous Metabolite	Metabolic Disease
1-Aminopropan-2-ol (Standard) is the analytical standard of 1-Aminopropan-2-ol. This product is intended for research and analytical applications. 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-A0060

Malotilate NKK 105	Lipoxygenase	Cancer
Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC₅₀=4.7 μM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes .

HY-113466

4-Hydroxynonenal 10+ Cited Publications 4-HNE	Aldehyde Dehydrogenase (ALDH) Endogenous Metabolite	Cardiovascular Disease Neurological Disease Cancer
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .

HY-113466S

4-Hydroxynonenal-d3 4-HNE-d₃	Isotope-Labeled Compounds Aldehyde Dehydrogenase (ALDH) Endogenous Metabolite	Cardiovascular Disease Neurological Disease Cancer
4-Hydroxynonenal-d₃ is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].

HY-N0538

Xylitol Xylite	Autophagy Endogenous Metabolite Bacterial Atg7 Atg8/LC3	Metabolic Disease Cancer
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

Cat. No.	Product Name	Type

HY-75884

2-(Triphenylphosphoranylidene)acetaldehyde	Biochemical Assay Reagents
2-(Triphenylphosphoranylidene)acetaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P4251

*Gly-Phe-Gly-Aldehyde* semicarbazone**	Peptides	Others
Gly-Phe-Gly-Aldehyde semicarbazone is a peptide.

HY-P4308

Z-Pro-Pro-aldehyde-dimethyl acetal	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015969

1-Aminopropan-2-ol Monoisopropanolamine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-W004661

1,4-Dioxane-2,5-diol Hydroxy acetaldehyde	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,4-Dioxane-2,5-diol is an endogenous metabolite.

HY-N1177

Taraxerone	Triterpenes Structural Classification Classification of Application Fields Terpenoids Crassulaceae Astragalus oleifolius DC. Source classification Sedum sarmentosum Bunge Plants Compositae Inflammation/Immunology Disease Research Fields	Aldehyde Dehydrogenase (ALDH)
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC₅₀ values of 512.42 and 500.16 μM, respectively .

HY-113466

4-Hydroxynonenal 10+ Cited Publications 4-HNE	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer	Aldehyde Dehydrogenase (ALDH) Endogenous Metabolite
4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria .

HY-N0538

Xylitol Xylite	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Cancer	Autophagy Endogenous Metabolite Bacterial Atg7 Atg8/LC3
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

HY-W015969R

1-Aminopropan-2-ol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
1-Aminopropan-2-ol (Standard) is the analytical standard of 1-Aminopropan-2-ol. This product is intended for research and analytical applications. 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

Cat. No.	Product Name	Chemical Structure

HY-141855S

Acetaldehyde 2,4-Dinitrophenylhydrazone-3,5,6-d3
Acetaldehyde 2,4-Dinitrophenylhydrazone-3,5,6-d₃ is the deuterium labeled Acetaldehyde 2,4-Dinitrophenylhydrazone-3,5,6[1].

HY-113466S

4-Hydroxynonenal-d3
4-Hydroxynonenal-d₃ is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].

4-Hydroxynonenal-d3

4-Hydroxynonenal-d₃ is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].

Cat. No.	Product Name		Classification

HY-N0538

Xylitol Xylite		Fillers
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

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Isotope-Labeled Compounds

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