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Results for "

acetylcholinesterase-inhibiting

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Apoptosis (4) Autophagy (1) Bacterial (1) Calcium Channel (2) Cholinesterase (ChE) (11) Endogenous Metabolite (1) Endothelin Receptor (1) G-quadruplex (1) Histamine Receptor (1) Insecticide (3) Isotope-Labeled Compounds (1) Kisspeptin Receptor (3) Monoamine Oxidase (1) NOD-like Receptor (NLR) (2) Reactive Oxygen Species (4) SARS-CoV (1) Telomerase (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (4) Neurological Disease (8)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0832

Profenofos	Cholinesterase (ChE)	Neurological Disease
Profenofos is an insecticida used on field crops, vegetables, and fruit crops. Profenofos is an acetylcholinesterase (AChE) inhibitor, with neurotoxicity .

HY-151370

AChE-IN-26	Cholinesterase (ChE)	Neurological Disease
AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor with an IC₅₀ value of 0.42 μM. AChE-IN-26 can be used for the research of Alzheimer’s disease .

HY-N7010

(-)-Corynoxidine	Cholinesterase (ChE) Bacterial	Infection
(-)-Corynoxidine is an *acetylcholinesterase* inhibitor with an IC₅₀ value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa . (-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees .

HY-B1946

Dimethoate 1 Publications Verification	Insecticide Reactive Oxygen Species Apoptosis	Inflammation/Immunology
Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active *acetylcholinesterase* inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .

HY-B0832R

Profenofos (Standard)	Cholinesterase (ChE)	Neurological Disease
Profenofos (Standard) is the analytical standard of Profenofos. This product is intended for research and analytical applications. Profenofos is an insecticida used on field crops, vegetables, and fruit crops. Profenofos is an acetylcholinesterase (AChE) inhibitor, with neurotoxicity .

HY-N10209

Paecilomide	Cholinesterase (ChE)	Others
Paecilomide is a pyridone alkaloid and *acetylcholinesterase* inhibitor .

HY-120479

Cythioate	Cholinesterase (ChE)	Neurological Disease
Cythioate is an organophosphorous insecticide and anthelmintic. Cythioate is an *acetylcholinesterase* inhibitor which interferes with neuromuscular transmission in ectoparastites .

HY-P1016

BQ-3020	Endothelin Receptor	Cardiovascular Disease
BQ-3020 is a selective endothelin receptor (ET_B receptor) agonist that displaces [ ¹²⁵I] ET-1 binding to ET_B receptors, with an IC₅₀ value of 0.2 nM. BQ-3020 elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research ¹ ².

HY-B0882S

Edrophonium-d5 chloride	Cholinesterase (ChE)	Neurological Disease
Edrophonium-d₅ (chloride) is the deuterium labeled Edrophonium chloride. Edrophonium chloride is a readily reversible acetylcholinesterase inhibitor; prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction.

HY-N15323

Samioside	Cholinesterase (ChE)	Infection Inflammation/Immunology
Samioside is an effective *acetylcholinesterase* inhibitor that can be isolated from Phlomis nissolii and P. capitata. Samioside possesses free-radical scavenging and antimicrobial activities. Samioside can be used in research on its anti-Alzheimer’s potency .

HY-126175

Neostigmine iodide	Endogenous Metabolite	Neurological Disease
Neostigmine iodide is a reversible acetylcholinesterase inhibitor with muscle tone-enhancing activity. Neostigmine iodide is primarily used to improve muscle function in patients with myasthenia gravis. Neostigmine iodide is also used in routine anesthesia to reverse the effects of nondepolarizing muscle relaxants such as rocuronium .

HY-P5544

M-TriDAP N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1/2 agoist and biological active peptide .

HY-P5544A

M-TriDAP TFA N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a NOD1/2 agoist and biological active peptide .

HY-B1946R

Dimethoate (Standard)	Insecticide Reactive Oxygen Species Apoptosis	Inflammation/Immunology
Dimethoate (Standard) is the analytical standard of Dimethoate. This product is intended for research and analytical applications. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active *acetylcholinesterase* inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice.

HY-B1946S

Dimethoate-d6	Isotope-Labeled Compounds Insecticide Reactive Oxygen Species Apoptosis	Others Inflammation/Immunology
Dimethoate-d₆ is the deuterium labeled Dimethoate. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active *acetylcholinesterase* inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .

HY-168031

AChE/BChE-IN-21	Histamine Receptor Calcium Channel Cholinesterase (ChE) Reactive Oxygen Species Amyloid-β	Neurological Disease
AChE/BChE-IN-21 is a histamine H₃ receptor antagonist, calcium channel blocker, and *acetylcholinesterase* inhibitor. AChE/BChE-IN-21 exhibits neuroprotective activity against H₂O₂ and Aβ_1-40, and can restore cognitive function in AD mice .

HY-P2424

Cholecystokinin-J CCK-J	Calcium Channel	Others
Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca ²⁺ release .

HY-P2161B

TAK-683 acetate 1 Publications Verification	Kisspeptin Receptor	Cancer
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P2161A

TAK-683 TFA	Kisspeptin Receptor	Cancer
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P2161

TAK-683	Kisspeptin Receptor	Cancer
TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-108477

TMPyP4 tosylate Maximum Cited Publications 7 Publications Verification TMP 1363	G-quadruplex Telomerase Cholinesterase (ChE) SARS-CoV	Cancer
TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand. TMPyP4 tosylate inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate is a telomerase inhibitor and inhibits cancer cells proliferation. TMPyP4 tosylate is also a stabilizer of nucleic acid secondary structure and an *acetylcholinesterase* inhibitor. Besides, TMPyP4 tosylate has antiviral activity against SARS-CoV-2 .

HY-156348

MAO-B-IN-26	Monoamine Oxidase Autophagy Apoptosis Cholinesterase (ChE)	Neurological Disease
MAO-B-IN-26 (Compound IC9) is a MAO-B and *acetylcholinesterase* inhibitor. MAO-B-IN-26 protects SH?SY5Y cells against Aβ induced cytotoxicity, morphological changes, ROS generation and membrane damage. MAO-B-IN-26 also inhibits Aβ induced autophagy and apoptosis. MAO-B-IN-26 can be used as a neuroprotective agent against Alzheimer’s disease .

Cat. No.	Product Name	Target	Research Area

HY-P5544

M-TriDAP N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a NOD1/2 agoist and biological active peptide .

HY-P2161B

TAK-683 acetate 1 Publications Verification	Kisspeptin Receptor	Cancer
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P1016

BQ-3020	Endothelin Receptor	Cardiovascular Disease
BQ-3020 is a selective endothelin receptor (ET_B receptor) agonist that displaces [ ¹²⁵I] ET-1 binding to ET_B receptors, with an IC₅₀ value of 0.2 nM. BQ-3020 elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research ¹ ².

HY-P5544A

M-TriDAP TFA N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA	NOD-like Receptor (NLR)	Others
M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a NOD1/2 agoist and biological active peptide .

HY-P2424

Cholecystokinin-J CCK-J	Calcium Channel	Others
Cholecystokinin-J (CCK-J), a cholecystokinin, stimulates Ca ²⁺ release .

HY-P2161A

TAK-683 TFA	Kisspeptin Receptor	Cancer
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

HY-P2161

TAK-683	Kisspeptin Receptor	Cancer
TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7010

(-)-Corynoxidine	Infection Alkaloids Classification of Application Fields Corydalis speciosa Maxim. Source classification Plants Isoquinoline Alkaloids Disease Research Fields Papaveraceae	Cholinesterase (ChE) Bacterial
(-)-Corynoxidine is an *acetylcholinesterase* inhibitor with an IC₅₀ value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa . (-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees .

HY-N10209

Paecilomide	Alkaloids Microorganisms Classification of Application Fields Source classification Other Diseases Pyridine Alkaloids Disease Research Fields	Cholinesterase (ChE)
Paecilomide is a pyridone alkaloid and *acetylcholinesterase* inhibitor .

HY-N15323

Samioside	Structural Classification Labiatae Phlomis nissolii L. Source classification Phenols Polyphenols Plants	Cholinesterase (ChE)
Samioside is an effective *acetylcholinesterase* inhibitor that can be isolated from Phlomis nissolii and P. capitata. Samioside possesses free-radical scavenging and antimicrobial activities. Samioside can be used in research on its anti-Alzheimer’s potency .

Cat. No.	Product Name	Chemical Structure

HY-B1946S

Dimethoate-d6
Dimethoate-d₆ is the deuterium labeled Dimethoate. Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active *acetylcholinesterase* inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .

HY-B0882S

Edrophonium-d5 chloride
Edrophonium-d₅ (chloride) is the deuterium labeled Edrophonium chloride. Edrophonium chloride is a readily reversible acetylcholinesterase inhibitor; prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction.

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acetylcholinesterase-inhibiting

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products