Search Result
Results for "
antioxidative effects
" in MedChemExpress (MCE) Product Catalog:
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0181
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- HY-W017378
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Drug Intermediate
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Others
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Trimethylhydroquinone is a key intermediate for the synthesis of Vitamin E or other trimethylhydroquinone derivatives with antioxidative effects .
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- HY-N7929
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Tyrosinase
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Cancer
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5-Feruloylquinic acid (5-FQA) possesses antioxidative effects and tyrosinase inhibitory activities .
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- HY-N5135
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Nolinospiroside F
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Others
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Others
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Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects .
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- HY-12840
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- HY-N10284
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Others
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Others
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Tetrahydroauroglaucin is a member of hydroquinones, with antioxidative effects .
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-
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- HY-N7937
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Others
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Inflammation/Immunology
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γ-Asarone, a phenylpropene, shows strong correlation with the biological activities (anti-oxidative, anti-inflammatory and neurotrophic effects) .
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-
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- HY-N11099
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Others
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Cardiovascular Disease
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(±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects .
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- HY-N3192
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Bacterial
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Infection
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Nervogenic acid is an aromatic compound that can be isolated from Piper elongatum VAHL. Nervogenic acid has antibacterial activities and antioxidative effects .
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-
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- HY-N2867
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Others
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Cancer
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Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP) .
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- HY-N0474
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- HY-N0344
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- HY-N0181R
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Ergosterin(Standard); Provitamin D(Standard); Provitamin D2 (Standard)
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Endogenous Metabolite
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Inflammation/Immunology
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Ergosterol (Standard) is the analytical standard of Ergosterol. This product is intended for research and analytical applications. Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
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- HY-N1181
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4'-O-Methyl Quercetin
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Endogenous Metabolite
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Inflammation/Immunology
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Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-oxidative and anti-inflammatory effects. Tamarixetin protects against cardiac hypertrophy .
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- HY-N7637
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Apoptosis
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Cancer
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Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects .
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- HY-N7675
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Others
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Cardiovascular Disease
Metabolic Disease
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Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities .
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-
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- HY-N0494
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Gentiopicrin
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Cytochrome P450
HCV
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Inflammation/Immunology
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Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
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- HY-N0765
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- HY-B1135
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- HY-N1947
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Others
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Others
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Ligurobustoside N (compound 2) is an antioxidative glycoside that can be isolated from the Leaves of Ligustrum robustum. Ligurobustoside N shows antioxidant effects and shows inhibition for AAPH (HY-Y0525) induced hemolysis .
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- HY-N7929R
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Tyrosinase
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Cancer
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5-Feruloylquinic acid (Standard) is the analytical standard of 5-Feruloylquinic acid. This product is intended for research and analytical applications. 5-Feruloylquinic acid (5-FQA) possesses antioxidative effects and tyrosinase inhibitory activities .
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- HY-N7675A
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Others
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Metabolic Disease
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(2R)-Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R)-Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities .
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- HY-N7766
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Apoptosis
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Inflammation/Immunology
Cancer
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Rubropunctatin, an orange azaphilone pigment, is isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctatin has anti-inflammatory, immunosuppressive and antioxidative effects, and also exhibits anti-tumor activity .
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- HY-W166297
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p38 MAPK
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Cancer
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Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway .
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- HY-N0474R
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NF-κB
Endogenous Metabolite
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Inflammation/Immunology
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Tyrosol (Standard) is the analytical standard of Tyrosol. This product is intended for research and analytical applications. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects .
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- HY-N5135R
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Others
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Others
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Liriopesides B (Standard) is the analytical standard of Liriopesides B. This product is intended for research and analytical applications. Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects .
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- HY-137390A
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Others
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Cardiovascular Disease
Metabolic Disease
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(3S,5R)-Fluvastatin (potassium) is a synthetic hypolipidemic drug that inhibits HMG-CoA reductase activity. (3S,5R)-Fluvastatin (potassium) has similar antioxidative effects on copper ion-induced LDL oxidation compared to its 3R,5S enantiomer. (3S,5R)-Fluvastatin (potassium) and its metabolites demonstrate a potential to exhibit anti-atherosclerotic effects through their antioxidative activities. (3S,5R)-Fluvastatin (potassium) is clinically utilized as part of a racemic mixture for reducing plasma cholesterol levels.
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- HY-N1181R
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Endogenous Metabolite
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Inflammation/Immunology
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Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-oxidative and anti-inflammatory effects. Tamarixetin protects against cardiac hypertrophy .
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- HY-N9975
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Others
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Inflammation/Immunology
Cancer
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4'',5''-Dehydroisopsoralidin is a β-glucuronidase inhibitor (IC50: 6.3 μM). 4'',5''-Dehydroisopsoralidin has anti-inflammatory and anti-oxidative effects. 4'',5''-Dehydroisopsoralidin can be used in the research of inflammation and cancners .
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- HY-N0520
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Calycosin-7-glucoside
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Reactive Oxygen Species
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Others
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Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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- HY-N0494R
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Cytochrome P450
HCV
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Inflammation/Immunology
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Gentiopicroside (Standard) is the analytical standard of Gentiopicroside. This product is intended for research and analytical applications. Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
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- HY-N0765R
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Fungal
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Infection
Neurological Disease
Inflammation/Immunology
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Isoliquiritin (Standard) is the analytical standard of Isoliquiritin. This product is intended for research and analytical applications. Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity .
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- HY-N10593
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Reactive Oxygen Species
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Cardiovascular Disease
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Ladanetin-6-O-β-D-glucopyranoside is an active flavonoid. Ladanetin-6-O-β-D-glucopyranoside has antioxidative effect. Ladanetin-6-O-β-D-glucopyranoside can be used for the research of cardioprotective effects .
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- HY-B1135R
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- HY-W015782
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Tyrosinase
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Metabolic Disease
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4-Ethylresorcinol, a derivative of resorcinol, can act as substrates of tyrosinase. 4-Ethylresorcinol possess hypopigmentary effects. 4-Ethylresorcinol attenuates mRNA and protein expression of tyrosinase-related protein (TRP)-2, and possessed antioxidative effect by inhibiting lipid peroxidation .
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- HY-145532
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Apoptosis
NF-κB
Keap1-Nrf2
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Inflammation/Immunology
Cancer
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S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation .
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- HY-N0502
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Reactive Oxygen Species
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Metabolic Disease
Cancer
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Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
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- HY-126397
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NF-κB
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Inflammation/Immunology
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MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research .
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- HY-N0814B
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Inositol hexaphosphate hexasodium; SNF472
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Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
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Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
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- HY-N0164
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Matrine
Maximum Cited Publications
12 Publications Verification
Matridin-15-one; Vegard; α-Matrine
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PINK1/Parkin
Opioid Receptor
Autophagy
Mitophagy
Ferroptosis
Apoptosis
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Inflammation/Immunology
Cancer
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Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) .
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- HY-N2447
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AMPK
Apoptosis
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Metabolic Disease
Cancer
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Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
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- HY-N0814
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Inositol hexaphosphate; SNF472 free acid
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Xanthine Oxidase
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
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Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .
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- HY-142026
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(+)-Vitisin A
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NF-κB
ERK
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Inflammation/Immunology
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Vitisin A has antioxidative, anticancer, antiapoptotic, neuroprotective and anti-inflammatory effects. Vitisin A inhibits LPS-induced NO and iNOS production via down-regulation of ERK1/2 and p38 and the NF-κB signal pathway. Vitisin A also inhibits adipocyte differentiation. Vitisin A is a resveratrol tetramer that can be isolated from Vitis vinifera roots .
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- HY-12554
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Vasopressin Receptor
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
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Terlipressin is a vasopressin analogue with potent vasoactive properties. Terlipressin is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin exerts anti-inflammatory and anti-oxidative effects. Terlipressin has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .
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- HY-N0115
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Gastrodine
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Apoptosis
Ferroptosis
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Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
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Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
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- HY-111827
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-
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- HY-12554A
-
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Vasopressin Receptor
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
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Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .
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- HY-N5021
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AHSYB
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Others
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Neurological Disease
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Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H2O2-induced cytotoxicity in cultured PC12 cells and primary neuronal cells .
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- HY-12554B
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Vasopressin Receptor
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
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Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .
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- HY-N0814A
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Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate
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Xanthine Oxidase
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
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Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .
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- HY-N0164R
-
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PINK1/Parkin
Opioid Receptor
Autophagy
Mitophagy
Ferroptosis
Apoptosis
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Inflammation/Immunology
Cancer
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Matrine (Standard) is the analytical standard of Matrine. This product is intended for research and analytical applications. Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) .
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- HY-N2447R
-
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AMPK
Apoptosis
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Metabolic Disease
Cancer
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Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
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- HY-15121S
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L-Glutamic Acid γ-ethyl amide-d5; Nγ-Ethyl-L-glutamine-d5
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Apoptosis
Endogenous Metabolite
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Neurological Disease
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L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide)is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].
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- HY-N0502R
-
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Reactive Oxygen Species
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Metabolic Disease
Cancer
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Mogroside V (Standard) is the analytical standard of Mogroside V. This product is intended for research and analytical applications. Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
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- HY-N0057
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3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
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Glycosidase
Influenza Virus
Apoptosis
Endogenous Metabolite
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Infection
Cancer
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3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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- HY-N0814R
-
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Xanthine Oxidase
Endogenous Metabolite
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Neurological Disease
Inflammation/Immunology
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Phytic acid (Standard) is the analytical standard of Phytic acid. This product is intended for research and analytical applications. Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .
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- HY-N0520R
-
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Reactive Oxygen Species
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Others
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Calycosin-7-O-β-D-glucoside (Standard) is the analytical standard of Calycosin-7-O-β-D-glucoside. This product is intended for research and analytical applications. Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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- HY-N9182
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Physalien
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Adiponectin Receptor
P2X Receptor
Autophagy
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Inflammation/Immunology
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Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (Kd=81.2 nM) and adiponectin receptor 1 (AdipoR1; Kd=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) .
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- HY-N1401
-
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MMP
Apoptosis
HSV
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Infection
Inflammation/Immunology
Cancer
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20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity . 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 μM for murine MHV-68 .
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- HY-N7676
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Marein
1 Publications Verification
|
AMPK
HDAC
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
|
Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .
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- HY-N0057R
-
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Glycosidase
Influenza Virus
Apoptosis
Endogenous Metabolite
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Infection
Cancer
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3,4-Dicaffeoylquinic acid (Standard) is the analytical standard of 3,4-Dicaffeoylquinic acid. This product is intended for research and analytical applications. 3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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- HY-N1441
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Afzelin
4 Publications Verification
Kaempferol-3-O-rhamnoside
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Mitochondrial Metabolism
PTEN
Autophagy
Bacterial
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Infection
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
|
Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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- HY-169103
-
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NO Synthase
COX
Cholinesterase (ChE)
Amyloid-β
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Neurological Disease
Inflammation/Immunology
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Neuroprotective agent 5 (compound 28) is a brain permeabilizing agent with anti-neuritis, anti-oxidative damage and neuroprotective effects. Neuroprotective agent 5 exhibits a potent NO inhibitory effect (EC50=0.49 μM), inhibits the release of proinflammatory factors PGE2 and TNF-α, downregulates the expression of iNOS and COX-2 proteins, and promotes the polarization of BV-2 cells from the proinflammatory M1 phenotype to the anti-inflammatory M2 phenotype. In addition, Neuroprotective agent 5 can also inhibit acetylcholinesterase (AChE) activity and Aβ42 aggregation in a dose-dependent manner. Neuroprotective agent 5 can be used for the study of Alzheimer's disease .
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- HY-N1401R
-
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MMP
Apoptosis
HSV
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Infection
Inflammation/Immunology
Cancer
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20(R)-Ginsenoside Rh2 (Standard) is the analytical standard of 20(R)-Ginsenoside Rh2. This product is intended for research and analytical applications. 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity . 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 μM for murine MHV-68 .
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- HY-N1441R
-
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Mitochondrial Metabolism
PTEN
Autophagy
Bacterial
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Infection
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
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Afzelin (Standard) is the analytical standard of Afzelin. This product is intended for research and analytical applications. Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-12554A
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Vasopressin Receptor
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
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Terlipressin diacetate is a vasopressin analogue with potent vasoactive properties. Terlipressin diacetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin diacetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin diacetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .
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- HY-12554B
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Vasopressin Receptor
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Cardiovascular Disease
Inflammation/Immunology
Endocrinology
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Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N0181
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-
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- HY-N7929
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-
-
- HY-N5135
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-
-
- HY-N0474
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-
-
- HY-N0344
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-
-
- HY-N10284
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-
-
- HY-N7937
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-
-
- HY-N11099
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-
-
- HY-N3192
-
-
-
- HY-N2867
-
-
-
- HY-N0181R
-
-
-
- HY-N1181
-
-
-
- HY-N7637
-
-
-
- HY-N7675
-
-
-
- HY-N0494
-
-
-
- HY-N0765
-
-
-
- HY-N1947
-
-
-
- HY-N7929R
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-
-
- HY-N7675A
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-
-
- HY-N7766
-
-
-
- HY-N0474R
-
-
-
- HY-N5135R
-
-
-
- HY-N1181R
-
-
-
- HY-N9975
-
-
-
- HY-N0520
-
-
-
- HY-N0494R
-
-
-
- HY-N0765R
-
-
-
- HY-N10593
-
-
-
- HY-W015782
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-
-
- HY-N0502
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-
-
- HY-N0814B
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Inositol hexaphosphate hexasodium; SNF472
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Structural Classification
other families
Ketones, Aldehydes, Acids
Source classification
Plants
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Endogenous Metabolite
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Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
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-
- HY-N0164
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-
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- HY-N2447
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-
-
- HY-N0814
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-
-
- HY-142026
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-
-
- HY-N0115
-
-
-
- HY-111827
-
-
-
- HY-N5021
-
-
-
- HY-N0814A
-
-
-
- HY-N0164R
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-
-
- HY-N2447R
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Structural Classification
Gentiana scabra Bunge
Iridoids
Terpenoids
Source classification
Gentianaceae
Phenols
Polyphenols
Plants
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AMPK
Apoptosis
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Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
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-
-
- HY-N0502R
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-
-
- HY-N0057
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3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
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Infection
Structural Classification
Caprifoliaceae
Classification of Application Fields
Ketones, Aldehydes, Acids
Source classification
Phenols
Polyphenols
Plants
Endogenous metabolite
Disease Research Fields
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Glycosidase
Influenza Virus
Apoptosis
Endogenous Metabolite
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3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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-
-
- HY-N0814R
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-
-
- HY-N0520R
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-
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- HY-N9182
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-
-
- HY-N1401
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-
-
- HY-N7676
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-
-
- HY-N0057R
-
|
Structural Classification
Caprifoliaceae
Ketones, Aldehydes, Acids
Source classification
Phenols
Polyphenols
Plants
Endogenous metabolite
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Glycosidase
Influenza Virus
Apoptosis
Endogenous Metabolite
|
3,4-Dicaffeoylquinic acid (Standard) is the analytical standard of 3,4-Dicaffeoylquinic acid. This product is intended for research and analytical applications. 3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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-
- HY-N1441
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-
- HY-N1401R
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-
- HY-N1441R
-
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Flavonols
Structural Classification
Flavonoids
Saururaceae
Houttuynia cordata Thunb.
Source classification
Phenols
Polyphenols
Plants
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Mitochondrial Metabolism
PTEN
Autophagy
Bacterial
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Afzelin (Standard) is the analytical standard of Afzelin. This product is intended for research and analytical applications. Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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Cat. No. |
Product Name |
Chemical Structure |
-
- HY-15121S
-
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L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide)is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].
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Cat. No. |
Product Name |
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Classification |
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- HY-N0181
-
|
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Cholesterol
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Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
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