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Results for "

behavioral effect

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Aminopeptidase (1) Amyloid-β (1) Bcl-2 Family (2) Biochemical Assay Reagents (1) Cytochrome P450 (2) Dopamine Receptor (1) Drug Metabolite (1) Endogenous Metabolite (5) GABA Receptor (1) HIF/HIF Prolyl-Hydroxylase (1) mAChR (1) Melanocortin Receptor (1) mGluR (1) Monoamine Oxidase (2) NO Synthase (1) Opioid Receptor (1) PARP (2) Phosphatase (1) Reactive Oxygen Species (2) ROCK (1) Serotonin Transporter (1) Survivin (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Endocrinology (1) Infection (2) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (14)

By Targets:

5-HT Receptor (2)

Aminopeptidase (1)

Amyloid-β (1)

Bcl-2 Family (2)

Biochemical Assay Reagents (1)

Cytochrome P450 (2)

Dopamine Receptor (1)

Drug Metabolite (1)

Endogenous Metabolite (5)

GABA Receptor (1)

HIF/HIF Prolyl-Hydroxylase (1)

mAChR (1)

Melanocortin Receptor (1)

mGluR (1)

Monoamine Oxidase (2)

NO Synthase (1)

Opioid Receptor (1)

PARP (2)

Phosphatase (1)

Reactive Oxygen Species (2)

ROCK (1)

Serotonin Transporter (1)

Survivin (2)

By Research Areas:

Cancer (2)

Cardiovascular Disease (1)

Endocrinology (1)

Infection (2)

Inflammation/Immunology (5)

Metabolic Disease (3)

Neurological Disease (14)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015780

1,4-Dimethoxybenzene	Endogenous Metabolite	Metabolic Disease
1,4-Dimethoxybenzene is an endogenous metabolite. 1,4-Dimethoxybenzene has an anti-anxiety effect, increasing atherogenic index (AI) levels in rabbits and inducing sedentary behavior. Sedentary behavior may increase blood cholesterol levels and disrupt blood lipids . 1,4-Dimethoxybenzene considers to be not clastogenic in the in vivo micronucleus test .

HY-W335972

N-Lauryldiethanolamine	Phosphatase	Others
N-Lauryldiethanolamine is an antistatic agent with a strong inhibitory effect on cell growth at 30 μM, showing some lysosomotropic behavior. N-Lauryldiethanolamine is toxic at a concentration of ?≥?10 μM in the osteogenesis inhibition assay .

HY-108519

AS1892802	ROCK	Neurological Disease
AS1892802 is a potent, orally active, and highly selective inhibitor of ROCK. The onset of antinociceptive effect of AS1892802 is as fast as those of Tramadol and Diclofenac. AS1892802 did not induce gastric irritation or abnormal behavior. AS1892802 is an attractive analgesic profile for the research of severe osteoarthritis pain .

HY-P3630

Stick Insect Hypertrehalosaemic Factor II	Biochemical Assay Reagents	Others
Stick Insect Hypertrehalosaemic Factor II is a synthetic peptide. Stick Insect Hypertrehalosaemic Factor II has the same FAB spectra, reversed-phase high-performance liquid chromatographic behavior, and biological behavior as the natural material. Stick Insect Hypertrehalosaemic Factor II can be used for the research of hypertrehalosaemic effect .

HY-117284

Eucatropine	mAChR	Neurological Disease
Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC₅₀ value of 0.583 μM. Eucatropine is an anticholinergic agent .

HY-P2429

N,N-Diallyl-Tyr-Aib-Aib-Phe-Leu	Opioid Receptor	Others
N,N-Diallyl-Tyr-Aib-Aib-Phe-Leu is a compound that can antagonize the δ-opioid receptor and the action of [D-Pen2,D-Pen?] enkephalin in vivo. Its antagonistic effect can be verified by specific behavioral experiments.

HY-103344

ZJ43	Aminopeptidase mGluR	Neurological Disease Inflammation/Immunology
ZJ43 is a potent NAAG peptidase inhibitor, with an IC₅₀ of 2.4 nM and a K_i of 0.8 nM. ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models .

HY-P2113

ORG-2766	Melanocortin Receptor	Neurological Disease
ORG-2766 is an adrenocorticotropic hormone ACTH 4-9 analog and neurotrophic peptide. ORG-2766 affects behavioral processes such as memory and attention in animals, improving symptoms in rats with experimental allergic neuritis. ORG-2766 has a neuroprotective effect .

HY-N12919

(E)-3-Dodecenol	Others	Endocrinology
(E)-3-Dodecenol is a termite trail pheromone that can be isolated from the whole body and thymus extracts of termite workers. (E)-3-Dodecenol induces orientational and recruitment behavior effects, but its induction effect is weaker than (Z)-Dodecenol or natural thymus extracts .

HY-W704749

7-Hydroxychlorpromazine hydrochloride	Drug Metabolite Dopamine Receptor	Neurological Disease
7-Hydroxychlorpromazine hydrochloride is the active metabolite of Chlorpromazine (HY-12708). 7-Hydroxychlorpromazine hydrochloride can increase prolactin levels in rats. 7-Hydroxychlorpromazine hydrochloride can increase dopamine turnover and has a sedative effect. In addition, 7-Hydroxychlorpromazine hydrochloride can effectively inhibit amphetamine-induced stereotyped behavior in rats and is used in the study of psychosis .

HY-W007223

D-5-Hydroxytryptophan D-5-HTP; 5-Hydroxy-D-tryptophan	5-HT Receptor	Neurological Disease
D-5-Hydroxytryptophan (D-5-HTP) is the D-isomer of 5-HTP and can be isolated from DL-5-hydroxytryptophan by continuous separation. Compared with intraperitoneal administration of L-5-Hydroxytryptophan, which can induce dose-dependent backward walking behavior in mice, D-5-Hydroxytryptophan has no significant effect on mouse behavior and is a negative control. D-5-Hydroxytryptophan is also a 5-HT ligand, capable of binding to the 5-HT site with affinity in the micromolar range .

HY-116807

Dihydrolipoic Acid 1 Publications Verification DHLA	Reactive Oxygen Species	Neurological Disease Inflammation/Immunology
Dihydrolipoic Acid (DHLA) is an excellent antioxidant capable of scavenging almost any oxygen-centered radical . Dihydrolipoic acid exhibits anti-inflammatory properties in various diseases. Dihydrolipoic Acid exerts a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Dihydrolipoic Acid can be used for the reaserch of depression .

HY-B2141

Bendazol	NO Synthase HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease Others Metabolic Disease
Bendazol is an orally effective antihypertensive agent. Bendazol acts directly on vascular smooth muscle to dilate blood vessels and reduce peripheral resistance, thereby improving blood circulation. Bendazol significantly inhibits the development of myopia in rabbit models. Bendazol can regulate kidney function by increasing the activity of NO synthase in the rat model of nephrogenic hypertension. In addition, Bendazol has an effect on sexual behavior and spermatogenesis in male rats .

HY-116807R

Dihydrolipoic Acid (Standard)	Reactive Oxygen Species	Neurological Disease Inflammation/Immunology
Dihydrolipoic Acid (Standard) is the analytical standard of Dihydrolipoic Acid. This product is intended for research and analytical applications. Dihydrolipoic Acid (DHLA) is an excellent antioxidant capable of scavenging almost any oxygen-centered radical . Dihydrolipoic acid exhibits anti-inflammatory properties in various diseases. Dihydrolipoic Acid exerts a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Dihydrolipoic Acid can be used for the reaserch of depression .

HY-146619

RAGE/SERT-IN-1	Amyloid-β Serotonin Transporter	Neurological Disease
RAGE/SERT-IN-1 is a potent and orally active advanced glycation end products (RAGE) and serotonin transporter (SERT) inhibitor with IC₅₀s of 8.26 μM and 31.09 nM, respectively. RAGE/SERT-IN-1 exhibits significant neuroprotective effect against Aβ_25-35-induced neuronal damage and alleviates depressive behavior of mice. RAGE/SERT-IN-1 can be used for researching the comorbidity of Alzheimer's disease and depression .

HY-17032

Indeloxazine (rac)-AS1069562 free base; YM-08054 free base	Endogenous Metabolite	Neurological Disease
Indeloxazine ((rac)-AS1069562 free base) is a brain active compound with anti-amnesic activity. Indeloxazine significantly prolonged the step latency in senescence accelerated mice (SAM-P/8/Ta), indicating that it has a promoting effect on brain function. Indeloxazine has a broader pharmacology than piracetam and exhibits stronger anti-amnesic activity. Indeloxazine has also been used as an anticonvulsant compound, further supporting its potential use in neuroprotection and behavioral improvement .

HY-W103463

1-Phenyl-2-pyrrolidinone 1-Phenylpyrrolidin-2-one	GABA Receptor	Neurological Disease
1-Phenyl-2-pyrrolidinone (1-Phenylpyrrolidin-2-one) is a phenyl analogue of GABA with sedative effect, decreasing the exploratory behavior of rats at 50-100 mg/kg (i.v.). 1-Phenyl-2-pyrrolidinone also has been proved to inhibit emotional reactions in dogs and cats. 1-Phenyl-2-pyrrolidinone induces decreases in the pressor reaction to emotional stress without accompanied by normalization of the function of baroreceptor reflexes .

HY-W004305R

Hexadecanal (Standard) Palmitaldehyde (Standard)	Endogenous Metabolite	Metabolic Disease
Hexadecanal (Standard) is an analytical standard for Hexadecanal. This product is intended for research and analytical applications. Hexadecanal (Palmitaldehyde), a volatile, long-chain fatty aldehyde, is released from human feces, skin, and breath. The hexadecanal receptor (OR37B) is highly conserved in mammals. Hexadecanal may exert its effects by modulating functional connectivity between social evaluation brain substrates and aggression execution brain substrates. Hexadecanal has also been shown to have a strong deterrent effect on black ants. Hexadecanal has potential for use in startle response and aggression behavior

HY-117387

BFE-37	Endogenous Metabolite	Infection
BFE-37 is a yeast introduction with heat resistance activity. The survival rate change of BFE-37 after heating at 55 °C for 5 minutes was 6.53 log CFU/mL, showing its strong heat resistance in acidic orange juice. The dynamic behavior of BFE-37 at different temperatures showed a first-order logarithmic linear inactivation characteristic, which indicates its stability in heat treatment. The study of BFE-37 helps to understand the effect of mild heat treatment on juice and provide guidance for microbial control in the food industry .

HY-163345

5-HT7R antagonist 2	5-HT Receptor	Neurological Disease
5-HT7R antagonist 2 (compound 4h) is a 5-HT7R antagonist that antagonizes the G protein and β-arrestin signaling pathways, with a K_i of 67 nM, the IC₅₀ values in cAMP and Tango tests were 2.59 μM and 39.57 μM, respectively. 5-HT7R antagonist 2 has an effect on neurogenesis and can reduce repetitive behaviors related to autism spectrum disorder (ASD) and restore neurogenesis of ASD impairment .

HY-103300

NPE-caged-proton	Endogenous Metabolite	Infection
NPE-caged-proton is a reagent that releases protons under UV light and has the activity of activating the fusion protein GP64 under weak acidic conditions. NPE-caged-proton can promote the binding of enveloped viruses to liposome membranes with acidic phospholipids in an environment of pH 4.0 to 5.5, thereby initiating membrane fusion. The ultraviolet unblocking effect of NPE-caged-proton can lower the environmental pH, thereby triggering the process of viral membrane fusion. When studying the interaction between viruses and cell membranes, NPE-caged-proton provides a valuable tool for revealing the subtle behaviors of viruses in different chemical and biochemical environments .

HY-B1311

Proadifen hydrochloride 1 Publications Verification SKF-525A; U-5446; RP-5171	Cytochrome P450 Monoamine Oxidase Bcl-2 Family Survivin PARP	Neurological Disease Inflammation/Immunology Cancer
Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC₅₀ value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases .

HY-B1311R

Proadifen (hydrochloride) (Standard)	Cytochrome P450 Monoamine Oxidase Bcl-2 Family Survivin PARP	Neurological Disease Inflammation/Immunology Cancer
Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [4] .

Cat. No.	Product Name	Target	Research Area