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Results for "

broad-spectrum antivirals

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (12) Apoptosis (4) Aurora Kinase (1) Autophagy (4) Bacterial (11) Btk (1) Cathepsin (3) CCR (2) CMV (4) Cytochrome P450 (3) Dengue virus (9) EBV (2) EGFR (2) Endogenous Metabolite (3) Enterovirus (2) FAK (1) Filovirus (3) Flavivirus (12) Fungal (3) Glucosidase (4) HBV (4) HCV (12) HIF/HIF Prolyl-Hydroxylase (2) HIV (10) HPV (3) HSV (7) Influenza Virus (20) Interleukin Related (3) Isotope-Labeled Compounds (3) JNK (1) LIM Kinase (LIMK) (1) Mitophagy (2) NF-κB (3) Nucleoside Antimetabolite/Analog (1) Orthopoxvirus (6) Parasite (7) PI3K (1) PROTACs (2) Reactive Oxygen Species (1) Reverse Transcriptase (2) RSV (6) SARS-CoV (33) Src (1) STAT (1) STING (1) TRP Channel (1) Virus Protease (3)
By Research Areas:	Cancer (16) Infection (87) Inflammation/Immunology (12) Neurological Disease (3)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108462

ML-SA1 3 Publications Verification	Dengue virus TRP Channel Flavivirus	Infection
ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC₅₀ value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral .

HY-N0306

Hederasaponin B	Enterovirus	Infection
Hederasaponin B, isolated from Hedera helix, has broad-spectrum *antiviral* activity against various subgenotypes of Enterovirus 71 (EV71).

HY-145275

EB-0176	Glucosidase	Infection
EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC₅₀s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses .

HY-145274

EB-0156	Glucosidase	Infection
EB-0156 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC₅₀s of 0.0479 and less than 0.001 μM, respectively. EB-0156 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0156 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses .

HY-145273

EB-0150	Glucosidase	Infection
EB-0150 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC₅₀s of 0.73 and 0.0337 μM, respectively. EB-0150 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0150 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses . EB-0150 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-146226

Viral 2C protein inhibitor 1	Enterovirus	Infection
Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC₅₀s of 0.1~3.6 µM, and exhibits high selectivity index and relatively low cytotoxicity .

HY-14837

Amizon Enisamium iodide	Influenza Virus SARS-CoV	Infection
Amizon (Enisamium iodide) is a broad-spectrum antiviral agent for influenza A and B. Amizon is an inhibitor for SARS-CoV-2 RNA polymerase .

HY-161454

Antiviral agent 54	Virus Protease Influenza Virus SARS-CoV	Infection
Antiviral agent 54 (compound 33) is a broad-spectrum and orally active antiviral agent. Antiviral agent 54 shows antiviral activity for ZIKV, HCoV-OC43 and influenza A virus (IVA). Antiviral agent 54 decreases the ZIKV RNA and protein level .

HY-122046

Amb123203	Endogenous Metabolite	Infection
Amb123203 is an antiviral compound with the activity of inhibiting viral budding. Amb123203 exerts its effect by blocking the interaction between mVP40 and Nedd4 proteins. Amb123203 has a significant inhibitory effect on the budding of VP40 virus-like particles (VLPs) of Marburg (MARV) and Ebola viruses. Amb123203 can effectively target RNA viruses that rely on the PPxY L domain for efficient budding, showing broad-spectrum antiviral activity. The discovery of Amb123203 provides an important basis for the development of new broad-spectrum antiviral compounds .

HY-157804

PROTAC SARS-CoV-2 Mpro degrader-1	PROTACs SARS-CoV	Infection
PROTAC SARS-CoV-2 Mpro degrader-1 (compound 5) is a PROTAC degrader targeting the major SARS-CoV-2 protease with broad-spectrum antiviral activity .

HY-16957

LJ001	HCV HIV	Infection
LJ001 is a broad-spectrum and orally active antiviral agent. LJ001 exerts antiviral activities by binding to viral membranes. LJ001 inhibits TGEV and PDCoV infection. LJ001 decreases TGEV N and PDCoV N-protein expression .

HY-120097

R-10015	LIM Kinase (LIMK) Reverse Transcriptase	Infection
R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC₅₀ of 38 nM for human LIMK1 .

HY-W018025

5,6-Dihydroxyindole	Bacterial Fungal Parasite Endogenous Metabolite	Infection Inflammation/Immunology
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, *antiviral, antiparasitic* activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-162690

DNA polymerase-IN-5	CMV	Infection
DNA polymerase-IN-5 (compound 42) is a broad-spectrum herpes antiviral. DNA polymerase-IN-5 against both CMV and VZV infection with IC₅₀ values of 6.6 and 4.8 μM .

HY-134608

Cobalt protoporphyrin IX Co-PPIX	Reactive Oxygen Species Influenza Virus	Infection
Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .

HY-80003

QL47	Flavivirus Dengue virus Btk	Infection Cancer
QL47, a broad-spectrum *antiviral* agent, inhibits dengue virus and other RNA viruses. QL47 selectively inhibits eukaryotic translation. QL47 is a potent covalent inhibitor of BTK with an IC₅₀ of 7 nM .

HY-12054

Hesperadin 5+ Cited Publications	Aurora Kinase Autophagy Influenza Virus Parasite	Cancer
Hesperadin is an ATP competitive indolinone inhibitor of Aurora A and B. Hesperadin inhibits Aurora B with an IC₅₀ of 250 nM. Hesperadin inhibits the growth of Trypanosoma brucei by blocking nuclear division and cytokinesis. Hesperadin also is a broad-spectrum influenza antiviral .

HY-162517

UMM-766	Orthopoxvirus	Infection
UMM-766 is an orally available nucleoside analog. UMM-766 has potent, broad-spectrum antiviral activity against multiple members of the pox virus family. UMM-766 provides protection in a murine model of orthopox disease .

HY-19961

KIN1408 1 Publications Verification	Flavivirus Dengue virus HCV	Infection
KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses .

HY-169224

SARS-CoV-2-IN-100	SARS-CoV	Infection
SARS-CoV-2-IN-100 (Compound 172) is an inhibitor of SARS-CoV-2, demonstrating broad-spectrum antiviral activity against various SARS-CoV-2 variants. SARS-CoV-2-IN-100 exhibits synergistic effects with Nirmatrelvir, which can reduce the risk of antiviral drug resistance .

HY-16468

Squalamine MSI-1256	Bacterial HBV FAK Dengue virus	Infection Neurological Disease Cancer
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ^,s disease mouse models .

HY-P99490

Burfiralimab hzVSF-v13	Interleukin Related SARS-CoV	Infection Inflammation/Immunology
Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies .

HY-18649B

Galidesivir dihydrochloride BCX4430 dihydrochloride; Immucillin-A dihydrochloride	Flavivirus	Infection
Galidesivir (BCX4430; Immucillin-A) dihydrochloride is a broad-spectrum RNA virus inhibitor that can inhibit Ebola and yellow fever virus (Flavivirus) infections. Galidesivir has potent antiviral activity against tick-borne encephalitis virus (TBEV) and also inhibits the proliferation of many other medically important flaviviruses .

HY-162701

Antiviral agent 58	SARS-CoV Influenza Virus RSV HSV	Infection
Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2 .

HY-16721

Cyclopropavir Filociclovir; ZSM-I-62; MBX-400	CMV HSV	Infection
Cyclopropavir (Filociclovir; ZSM-I-62; MBX-400) is a broad-spectrum anti-herpesvirus compound, has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 with EC₅₀s of 0.7 μM to 8 μM .

HY-119098

GSK983	EBV HPV	Infection
GSK983 is a broad-spectrum antiviral agent. GSK983 inhibits the replication of adenovirus-5 (Ad-5) and polyoma virus SV40. GSK983 inhibits the growth of cell lines immortalized by EBV, HTLV1, HPV. GSK983 induces the expression of interferon-stimulated genes .

HY-108016

Peruvoside Encordin	Src PI3K JNK STAT EGFR Apoptosis Autophagy	Cancer
Peruvoside is a potent inhibitor of Src, PI3K, JNK, STAT, and EGFR. Peruvoside induces apoptosis and autophagy and possesses a broad spectrum of anticancer activity in breast, lung, liver cancers and leukemia. Peruvoside is a broad-spectrum and potent antiviral activity against positive-sense RNA viruses. Peruvoside sensitizes Gefitinib (HY-50895)-resistant tumour cells (A549, PC9/gef and H1975) to Gefitinib .

HY-N12697A

Polycarpine hydrochloride	SARS-CoV Virus Protease Influenza Virus Fungal	Infection
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC₅₀ = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC₅₀ values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively .

HY-128423A

Tylvalosin Acetylisovaleryltylosin	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Tylvalosin (Acetylisovaleryltylo?sin) is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-14904A

Umifenovir hydrochloride 5+ Cited Publications	Influenza Virus SARS-CoV	Infection
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .

HY-168034

diABZI-4	STING	Infection Inflammation/Immunology
diABZI-4 is an oral active STING agonist with broad-spectrum antiviral activity. diABZI-4 induces the production of pro-inflammatory cytokines and lymphocyte activation by activating STING, thereby inhibiting the replication of influenza A virus (IAV), SARS-CoV-2, and human rhinovirus (HRV), with an EC₅₀ range of 11.8-199 nM .

HY-W018025R

5,6-Dihydroxyindole (Standard)	Bacterial Fungal Parasite Endogenous Metabolite	Infection Inflammation/Immunology
5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-13986

Merimepodib 2 Publications Verification VX-497; MMPD	Flavivirus Dengue virus HBV HCV	Infection Cancer
Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities.

HY-128718

Carbodine	Influenza Virus	Infection
Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent active against DNA viruses, (+)RNA viruses, (-)RNA viruses, paramyxo, rhabdo and (+/-)RNA viruses, targets CTP synthetase that converts UTP to CTP. Carbodine (Carbocyclic cytidine) possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro .

HY-139663

IHVR-17028	Glucosidase	Infection
IHVR-17028 is a potent and broad-spectrum *antiviral* agent. IHVR-17028 exhibits antiviral activity against BVDV, TCRV and DENV with EC₅₀ values of 0.4 μM, 0.26 μM, 0.3 μM, respectively. IHVR-17028 is a potent ER α-glucosidase I inhibitor with an IC₅₀ of 0.24 μM. IHVR-17028 can be used for infectious diseases research .

HY-128423

Tylvalosin tartrate Acetylisovaleryltylosin tartrate	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology
Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-107801

Inosine pranobex 1 Publications Verification Imunovir; Delimmun; Groprinosin	Interleukin Related HSV HIV HPV	Infection Inflammation/Immunology
Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus .

HY-14904

Umifenovir 5+ Cited Publications	SARS-CoV Influenza Virus	Infection
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells . Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro . Umifenovir shows anti-inflammatory activity .

HY-109035

Inarigivir soproxil 1 Publications Verification SB9200; GS-9992	HCV HBV	Infection
Inarigivir soproxil (SB9200) is an agonist of innate immunity and shows potent antiviral activity against resistant HCV variants, with EC₅₀s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. Inarigivir soproxil, an orally bioavailable proagent of SB 9000, has broad-spectrum antiviral activity against RNA viruses including HCV, norovirus, respiratory syncytial virus and influenza and HBV .

HY-W015764

T-1105 1 Publications Verification	Flavivirus	Infection
T-1105, a structural analogue of T-705, is a novel broad-spectrum viral polymerase inhibitor. T-1105 inhibits the polymerases of RNA viruses after being converted to ribonucleoside triphosphate (RTP) metabolite. T-1105 has *antiviral* activity against various RNA viruses. T-1105 can be formed by nicotinamide mononucleotide adenylyltransferase .

HY-14904AS

Umifenovir-d6 hydrochloride	Isotope-Labeled Compounds Influenza Virus SARS-CoV	Infection
Umifenovir-d₆ (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3].

HY-14904AR

Umifenovir hydrochloride (Standard)	Influenza Virus SARS-CoV	Infection
Umifenovir (hydrochloride) (Standard) is the analytical standard of Umifenovir (hydrochloride). This product is intended for research and analytical applications. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .

HY-B1080

Tilorone dihydrochloride 2 Publications Verification	HIF/HIF Prolyl-Hydroxylase Influenza Virus	Infection Neurological Disease
Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS .Tilorone dihydrochloride exhibits an inhibitory activity with EC₅₀ of 230 nM against Ebola virus (EBOV) .

HY-161342

CTSL/CAPN1-IN-2	Cathepsin SARS-CoV	Infection Inflammation/Immunology
CTSL/CAPN1-IN-2 (Compound 14b) is an orally active inhibitor of both CTSL and CAPN1, with IC₅₀ values of 6.88 nM and 347.6 nM, respectively. CTSL/CAPN1-IN-2 possesses anti-inflammatory properties and favorable pharmacokinetic characteristics. CTSL/CAPN1-IN-2 exhibits broad-spectrum antiviral activity against coronaviruses by blocking viral entry .

HY-B0434

Ribavirin 30+ Cited Publications Ribasphere	HCV RSV Orthopoxvirus Antibiotic	Infection Cancer
Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

HY-100528

Nanchangmycin 2 Publications Verification Nanchangmycin A	Bacterial Antibiotic Flavivirus	Infection
Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .

HY-161956

Antiviral agent 59	Filovirus	Infection
Antiviral agent 59 (compound 58) is an *antiviral* agent with selective and drug-like properties that inhibits a broad spectrum of filoviruses. Antiviral agent 59 exhibits low off-target activity and inhibition against replication-competent Ebola virus (EBOV), Sudan virus (SUDV), and Marburg virus (MARV/b>) .

HY-B0434S

Ribavirin-13C5 Ribasphere-¹³C₅	Isotope-Labeled Compounds HCV RSV Antibiotic	Infection
Ribavirin- ¹³C₅ is the ¹³C-labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.

HY-150625

SARS-CoV-2 nsp13-IN-4	SARS-CoV	Infection
SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC₅₀ value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum *antiviral* effect .

HY-118326

MRT 68601	Others	Cancer
MRT 68601 is a potent TBK1 inhibitor with the activity of inhibiting autophagosome formation in lung cancer cells. MRT 68601 may have potential effects against targets associated with host-dependent factors identified in SARS-CoV-2 infection. The drug targets involved in MRT 68601 are related to existing FDA-approved drugs and compounds in clinical trials, which can provide support for the development of broad-spectrum antiviral therapies .

Cat. No.	Product Name	Type

HY-B0434G

Ribavirin (GMP) Ribasphere (GMP); ICN-1229 (GMP)	Fluorescent Dye
Ribavirin (GMP) is Ribavirin (HY-B0434) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

Cat. No.	Product Name	Type

HY-B0434G

Ribavirin (GMP) Ribasphere (GMP); ICN-1229 (GMP)	Biochemical Assay Reagents
Ribavirin (GMP) is Ribavirin (HY-B0434) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

Cat. No.	Product Name	Target	Research Area

HY-P10467

ALPS1 peptide from ArfGAP1	Peptides	Infection
ALPS1 peptide from ArfGAP1 is a curvature selective peptide from ArfGAP1 ALPS1 motif. Curvature selectivity can be used to develop broad-spectrum antiviral peptides .

HY-P3626

Astodrimer SPL7013 free base	Bacterial HCV SARS-CoV	Infection
Astodrimer (SPL7013 free base) is a large (3-4 nm, ~ 16.5 kDa), negatively charged, highly-branched dendrimer, is a potent virucidal agent. Astodrimer shows antiviral and virucidal activity against a broad spectrum of viruses, including SARS-CoV-2, HIV-1, HSV-1, HSV-2, HPV. Astodrimer also has antibacterial properties .

Cat. No.	Product Name	Target	Research Area

HY-P99490

Burfiralimab hzVSF-v13	Interleukin Related SARS-CoV	Infection Inflammation/Immunology
Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0306

Hederasaponin B	Infection Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Araliaceae	Enterovirus
Hederasaponin B, isolated from Hedera helix, has broad-spectrum *antiviral* activity against various subgenotypes of Enterovirus 71 (EV71).

HY-W018025

5,6-Dihydroxyindole	Structural Classification Natural Products Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, *antiviral, antiparasitic* activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-16468

Squalamine MSI-1256	Infection Triterpenes Structural Classification Animals Classification of Application Fields Terpenoids Marine natural products Other marine organisms Disease Research Fields Cancer	Bacterial HBV FAK Dengue virus
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ^,s disease mouse models .

HY-108016

Peruvoside Encordin	Apocynaceae Triterpenes Structural Classification Terpenoids Source classification Thevetia peruviana (Pers.) K. Schum. Plants	Src PI3K JNK STAT EGFR Apoptosis Autophagy
Peruvoside is a potent inhibitor of Src, PI3K, JNK, STAT, and EGFR. Peruvoside induces apoptosis and autophagy and possesses a broad spectrum of anticancer activity in breast, lung, liver cancers and leukemia. Peruvoside is a broad-spectrum and potent antiviral activity against positive-sense RNA viruses. Peruvoside sensitizes Gefitinib (HY-50895)-resistant tumour cells (A549, PC9/gef and H1975) to Gefitinib .

HY-100528

Nanchangmycin 2 Publications Verification Nanchangmycin A	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields Polyether Antibiotics	Bacterial Antibiotic Flavivirus
Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .

HY-100528A

Dianemycin 2 Publications Verification Nanchangmycin free acid	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields Polyether Antibiotics	Bacterial Antibiotic Flavivirus
Dianemycin (Nanchangmycin free acid), a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .

HY-15310

Ivermectin Maximum Cited Publications 25 Publications Verification MK-933; CD-5024; K-237	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antiviral Anti-parasitic Disease Research Disease Research Fields Cancer	Flavivirus Dengue virus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

HY-N12697A

Polycarpine hydrochloride	Structural Classification Alkaloids Animals Other Alkaloids Source classification	SARS-CoV Virus Protease Influenza Virus Fungal
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC₅₀ = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC₅₀ values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively .

HY-W018025R

5,6-Dihydroxyindole (Standard)	Structural Classification Natural Products Source classification Phenols Polyphenols Endogenous metabolite	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-N11667

18-O-Demethylpederin	Structural Classification Natural Products Source classification Marine natural products Other marine organisms	Others
18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor .

HY-15310R

Ivermectin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antiviral Anti-parasitic Disease Research	Dengue virus Flavivirus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (Standard) is the analytical standard of Ivermectin. This product is intended for research and analytical applications. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

Cat. No.	Product Name	Chemical Structure

HY-14904AS

Umifenovir-d6 hydrochloride

Umifenovir-d₆ (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3].

HY-135853S

Molnupiravir-d7

Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].