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cone

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

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1

Peptides

7

Natural
Products

1

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122966
    Desmethylxanthohumol
    1 Publications Verification

    Apoptosis Cancer
    Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities .
    Desmethylxanthohumol
  • HY-P2325

    Biochemical Assay Reagents Neurological Disease
    Exoenzyme C3, clostridium botulinum is a promising agent to inactivate RhoA in neurons due to preventing the detrimental effect of active Rho in the recovery of injured neuronal systems. Exoenzyme C3, clostridium botulinum is used for the study of post-traumatic neuro-regeneration .
    Exoenzyme C3, clostridium botulinum
  • HY-N2787
    8-​Prenylnaringenin
    1 Publications Verification

    Apoptosis Cancer
    8-prenylnaringenin is a prenylflavonoid isolated from hop cones Humulus lupulus, with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice .
    8-​Prenylnaringenin
  • HY-N3612A

    (-)-Communic acid

    Others Others
    trans-Communic acid is a diterpenoid. trans-Communic acid can be isolated from ethyl acetate extract of young cones of hinoki (Chamaecyparis obtusa Endl.) .
    trans-Communic acid
  • HY-N13186

    Bacterial Infection
    δ-(E)-Deoxy-amplexichromanol is a δ-tocotrienolic acid derivative with potent antibacterial activities, which is derivated from hydromethanolic extract of the cones of C. atlantica .
    δ-(E)-Deoxy-amplexichromanol
  • HY-B1740

    Microtubule/Tubulin Neurological Disease
    Pregnenolone acetate (compound #43), a nonmetabolized Pregnenolone (HY-B0151) analog, can promote neurite extension and induce a change in growth cone morphology in primary cultures of cerebellar granule neurons. Pregnenolone acetate, a neurosteroid, increases microtubule polymerization. Pregnenolone acetate has the potential for neurodevelopmental diseases research .
    Pregnenolone acetate
  • HY-P1287

    iGluR Neurological Disease
    Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa .
    Conantokin-T
  • HY-N11976

    Others Others
    Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .
    Glycyrrhizin-6′′-methylester
  • HY-N7178

    Others Others
    Abieta-8,11,13-triene-7α,15,18-triol is an abietane diterpene. Abieta-8,11,13-triene-7α,15,18-triol can be isolated from the CHCl3 extract of the cones of Larix koempferi .
    Abieta-8,11,13-triene-7α,15,18-triol
  • HY-N1659

    Others Others
    2,3-Dihydropodocarpusflavone A is a biflavonoid, which can be isolated from Cycas beddomei .
    2,3-Dihydropodocarpusflavone A
  • HY-103511

    GABA Receptor Neurological Disease
    TCS1105 is a benzodiazepine ligand with agonist for α2-subunit containing GABAA receptors and antagonist for α1-subunit containing GABAA receptors. TCS1105 reduces anxiety-like behavior in mice. TCS1105 enhances offensive behavior and social dominance. TCS1105 blocks Sema3A induced AGC (axonal growth cones) collapse in a concentration-dependent fashion .
    TCS1105

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