Search Result
Results for "
deuterated compound
" in MedChemExpress (MCE) Product Catalog:
31
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-101411S
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- HY-100442S1
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- HY-17479BS
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Isotope-Labeled Compounds
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Others
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Amfenac-d5 sodium is deuterated-labeled Amfenac sodium. Amfenac Sodium is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac Sodium can be used for the research of acute and chronic inflammation .
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- HY-W017162S
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- HY-50856S
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CTP-543; Ruxolitinib d8; deuterated Ruxolitinib
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JAK
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Inflammation/Immunology
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Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), modulates the activity of JAK1/JAK2. Deuruxolitinib can be used for the research hair loss disorders (from patent WO2017192905A1, compound I) .
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- HY-100442S
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ABR-215757-d5; ABR 25757-d5
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SARS-CoV
Isotope-Labeled Compounds
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Metabolic Disease
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Paquinimod-d5 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .
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- HY-B0535AS
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Emb-d4 dihydrochloride
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Antibiotic
Bacterial
Isotope-Labeled Compounds
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Infection
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Ethambutol-d4 dihydrochloride is deuterated labeled Ethambutol dihydrochloride (HY-B0535A). Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity.
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- HY-10882S1
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- HY-W089800S
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trans-2-Nonen-1-al-d2
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Biochemical Assay Reagents
Isotope-Labeled Compounds
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Others
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trans-2-Nonenal-d2 is deuterated labeled Acetylpyrazine (HY-W007692). Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) .
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- HY-N8016S1
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Isotope-Labeled Compounds
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Metabolic Disease
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Nonanal-d4 is deuterated labeled Methyl propyl disulfide (HY-N7436). Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .
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- HY-W127532S
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Biochemical Assay Reagents
Isotope-Labeled Compounds
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Others
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cis-4-Hepten-1-ol-d2 is deuterated labeled 4-Ethyloctanoic acid (HY-W015307). 4-Ethyloctanoic acid is a natural compound first isolated from Saussurea lappa Clarke, widely used as a safe flavoring compound and acts as food additive .
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- HY-141629S1
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- HY-149892S
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JAK
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Cancer
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TYK2?JH2-IN-1-d3 is the a deuterated, orally active and selective TYK2 inhibitor (compound 4h), targeting to JH2 domain (IC50=0.1 nM) .
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- HY-10201S
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Donafenib; Bay 43-9006-d3
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Raf
VEGFR
FLT3
Ferroptosis
Autophagy
Apoptosis
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Cancer
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Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively .
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- HY-163312S
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JAK
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Inflammation/Immunology
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Tyk2-IN-18-d5 (Compound 13) is the deuterated TYK2 inhibitor, targeting to JH2 domain. Tyk2-IN-18-d5 can be used for the research of inflammatory and autoimmune diseases .
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- HY-163591
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Histone Methyltransferase
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Cancer
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PRMT5-IN-36-d3 is the deuterated derivative of PRMT5-IN-36. PRMT5-IN-36-d3 (compound 4) is an orally active PRMT5 inhibitor for cancer research .
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- HY-12650S1
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- HY-34439S1
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- HY-168547S
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Parasite
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Infection
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AR89-d6 (Compound AR102) is a deuterated derivative of AR89 with oral activity. AR89-d6 demonstrates activity against S. mansoni, S. haematobium, and S. japonicum, and can be utilized for research on schistosomiasis .
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- HY-15331
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Vitamin D3-26,26,26,27,27,27-d6
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VD/VDR
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Metabolic Disease
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VD3-d6 (Vitamin D3-26,26,26,27,27,27-d6) is deuterated VD3. Compounds labeled with stable or radioactive isotopes can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-Y0078S1
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PPAR
Isotope-Labeled Compounds
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Metabolic Disease
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Cinnamyl Alcohol-d9 is deuterated labeled 3-Methoxyphenol (HY-Y1840). 3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
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- HY-W013014S
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Endogenous Metabolite
Isotope-Labeled Compounds
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Metabolic Disease
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3-Methyl-2-cyclopenten-1-one-d3 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate is a fragrance ingredient used in many fragrance compounds. Ethyl cinnamate is a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues .
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- HY-W017141S1
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Isotope-Labeled Compounds
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Others
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2-Isobutyl-3-methoxypyrazine-d9 is deuterated labeled cis-4-Hepten-1-ol (HY-W127532). cis-4-Hepten-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W042181S
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Didecyldimethylammonium-d6 chloride; DDAC-d6
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Isotope-Labeled Compounds
Bacterial
Fungal
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Infection
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N-Decyl-N,N-dimethyldecan-1-aminium-d6 (chloride) is a deuterated labeled N-Decyl-N,N-dimethyldecan-1-aminium (chloride) . N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties .
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- HY-145397S
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Isotope-Labeled Compounds
Topoisomerase
ADC Cytotoxin
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Cancer
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(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan . (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W102449S
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1-(4-(Methylamino)phenyl)ethanone-13C,d3
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Isotope-Labeled Compounds
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Others
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4-Acetyl-N-methylaniline-13C,d3 (1-(4-(Methylamino)phenyl)ethanone-13C,d3) is a 13C and deuterated isotope of 4-Acetyl-N-methylaniline. Compounds labeled with stable or radioactive isotopes can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-N8015S1
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Bacterial
Endogenous Metabolite
Isotope-Labeled Compounds
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Cancer
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Octanal-d2 is deuterated labeled Myrcene (HY-N0803). Myrcene (β-Myrcene) is a type of aromatic compound that inhibits TNFα and NF-κB activity. Myrcene has anti-invasive action, inhibits cell cycle, and leads to cancer cell apoptosis. Myrcene has strong blood protection effect, anti-inflammation, and anti-inflammatory activity .
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- HY-N0709S1
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Bacterial
Fungal
Isotope-Labeled Compounds
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Cancer
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Coumarin-d6 is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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- HY-N8016S2
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Isotope-Labeled Compounds
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Metabolic Disease
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Nonanal-d2 is deuterated labeled Methyl cinnamate (HY-W017212). Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway .
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- HY-N1369S1
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Calcium Channel
Isotope-Labeled Compounds
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Neurological Disease
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Menthol-d2 is deuterated labeled trans-2,cis-6-Nonadienal (HY-W127515). Trans-2, cis-6-NonadienalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2, cis-6-NonadienalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-101411S
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4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .
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- HY-100442S1
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Paquinimod-d5-1 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .
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- HY-17479BS
-
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Amfenac-d5 sodium is deuterated-labeled Amfenac sodium. Amfenac Sodium is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac Sodium can be used for the research of acute and chronic inflammation .
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- HY-W017162S
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DL-3-Phenyllactic acid-d3 is a deuterated labeled DL-3-Phenyllactic acid . DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.
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- HY-100442S
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Paquinimod-d5 is a deuterated analog of Paquinimod (HY-100442). Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice .
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- HY-B0535AS
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Ethambutol-d4 dihydrochloride is deuterated labeled Ethambutol dihydrochloride (HY-B0535A). Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity.
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- HY-12215S2
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Deulorlatinib (compound A), a deuterated derivative of Lorlatinib (HY-12215), is a potent inhibitor of tyrosine kinase demonstrating desirable safety and durable activity in ALK-positive advanced NSCLC .
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- HY-10882S1
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Clotrimazole-d10 is deuterated labeled Clotrimazole (HY-10882). Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.
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- HY-W089800S
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trans-2-Nonenal-d2 is deuterated labeled Acetylpyrazine (HY-W007692). Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) .
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- HY-N8016S1
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Nonanal-d4 is deuterated labeled Methyl propyl disulfide (HY-N7436). Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .
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- HY-50856S
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Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), modulates the activity of JAK1/JAK2. Deuruxolitinib can be used for the research hair loss disorders (from patent WO2017192905A1, compound I) .
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- HY-W127532S
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cis-4-Hepten-1-ol-d2 is deuterated labeled 4-Ethyloctanoic acid (HY-W015307). 4-Ethyloctanoic acid is a natural compound first isolated from Saussurea lappa Clarke, widely used as a safe flavoring compound and acts as food additive .
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- HY-141629S1
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N-Palmitoyl-D-sphingomyelin-13C is a deuterated labeled N-Palmitoyl-D-sphingomyelin . N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
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- HY-149892S
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TYK2?JH2-IN-1-d3 is the a deuterated, orally active and selective TYK2 inhibitor (compound 4h), targeting to JH2 domain (IC50=0.1 nM) .
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- HY-10201S
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Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively .
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- HY-163312S
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Tyk2-IN-18-d5 (Compound 13) is the deuterated TYK2 inhibitor, targeting to JH2 domain. Tyk2-IN-18-d5 can be used for the research of inflammatory and autoimmune diseases .
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- HY-163591
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PRMT5-IN-36-d3 is the deuterated derivative of PRMT5-IN-36. PRMT5-IN-36-d3 (compound 4) is an orally active PRMT5 inhibitor for cancer research .
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- HY-12650S1
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Mirogabalin-d4 (DS5565-d4) is a deuterated compound of Mirogabalin (HY-12650), a ligand that selectively targets the voltage-sensitive calcium channel complex α2δ-1 .
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- HY-34439S1
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2,5-Dimethylpyrazine-d3 is deuterated labeled γ-Terpinene (HY-W020183). γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity .
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- HY-168547S
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AR89-d6 (Compound AR102) is a deuterated derivative of AR89 with oral activity. AR89-d6 demonstrates activity against S. mansoni, S. haematobium, and S. japonicum, and can be utilized for research on schistosomiasis .
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- HY-15331
-
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VD3-d6 (Vitamin D3-26,26,26,27,27,27-d6) is deuterated VD3. Compounds labeled with stable or radioactive isotopes can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-Y0078S1
-
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Cinnamyl Alcohol-d9 is deuterated labeled 3-Methoxyphenol (HY-Y1840). 3-Methoxyphenol is a phenolic compound that is biologically toxic. 3-Methoxyphenol is systemically absorbed, disrupts the function of the liver, kidneys, central nervous system, and redox processes, and increases levels of Hb, red blood cells, and white blood cells in the body.
|
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- HY-W013014S
-
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3-Methyl-2-cyclopenten-1-one-d3 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate is a fragrance ingredient used in many fragrance compounds. Ethyl cinnamate is a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues .
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- HY-W017141S1
-
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2-Isobutyl-3-methoxypyrazine-d9 is deuterated labeled cis-4-Hepten-1-ol (HY-W127532). cis-4-Hepten-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W042181S
-
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N-Decyl-N,N-dimethyldecan-1-aminium-d6 (chloride) is a deuterated labeled N-Decyl-N,N-dimethyldecan-1-aminium (chloride) . N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties .
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- HY-145397S
-
|
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(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan . (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W102449S
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4-Acetyl-N-methylaniline-13C,d3 (1-(4-(Methylamino)phenyl)ethanone-13C,d3) is a 13C and deuterated isotope of 4-Acetyl-N-methylaniline. Compounds labeled with stable or radioactive isotopes can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-N8015S1
-
|
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Octanal-d2 is deuterated labeled Myrcene (HY-N0803). Myrcene (β-Myrcene) is a type of aromatic compound that inhibits TNFα and NF-κB activity. Myrcene has anti-invasive action, inhibits cell cycle, and leads to cancer cell apoptosis. Myrcene has strong blood protection effect, anti-inflammation, and anti-inflammatory activity .
|
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- HY-N0709S1
-
|
|
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Coumarin-d6 is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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- HY-N8016S2
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Nonanal-d2 is deuterated labeled Methyl cinnamate (HY-W017212). Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway .
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- HY-N1369S1
-
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Menthol-d2 is deuterated labeled trans-2,cis-6-Nonadienal (HY-W127515). Trans-2, cis-6-NonadienalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2, cis-6-NonadienalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.
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