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Results for "

dithiol

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Fluorescent Dye

3

Biochemical Assay Reagents

2

Peptides

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W016149
    4,5-Dichloro-3H-1,2-dithiol-3-one

    Dichloro-1,2-dithiacyclopentenone

    		 Bacterial Infection
    4,5-Dichloro-3H-1,2-dithiol-3-one (Dichloro-1,2-dithiacyclopentenone) is an E. coli FabH inhibitor (IC50: 2.9 µM). 4,5-Dichloro-3H-1,2-dithiol-3-one can be used as a slimicide in the manufacture of food-contact paper and paperboard .
    4,5-Dichloro-3H-1,2-dithiol-3-one
  • HY-P3159
    VPM peptide

    		Biochemical Assay Reagents Others
    VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .
    VPM peptide
  • HY-D1258
    AC-green

    VDP-green

    		 Fluorescent Dye Others
    AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
    AC-green
  • HY-W741573
    N-Biotinyl p-aminophenyl arsenic acid

    		nAChR Neurological Disease
    N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that can bind to both streptavidin and dithiols. N-Biotinyl p-aminophenyl arsenic acid decreases the Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors (IC50 is 10-300 nM), and protects the receptor from irreversible alkylation by bromoacetylcholine .
    N-Biotinyl p-aminophenyl arsenic acid
  • HY-151182S
    1,3-Propane-dithiol-d6

    		Isotope-Labeled Compounds Others
    1,3-Propane-dithiol-d6 is the deuterium labeled 1,3-Propane-dithiol[1].
    1,3-Propane-dithiol-d6
  • HY-139480B
    Poly(ethylene glycol) dithiol (Mn 1500)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) dithiol (Mn 1500) is a thiol-modified PEG that can be used to synthesize dithiol-terminated amphiphilic diblock copolymers for drug delivery .
    Poly(ethylene glycol) dithiol (Mn 1500)
  • HY-139480A
    Poly(ethylene glycol) dithiol (Mn 1000)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) dithiol (Mn 1000) is a thiol-modified PEG that can be used to synthesize dithiol-terminated amphiphilic diblock copolymers for drug delivery .
    Poly(ethylene glycol) dithiol (Mn 1000)
  • HY-139480
    Poly(ethylene glycol) dithiol (Mn 3400)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) dithiol (Mn 3400) is a polymer and can be used as a biomaterial to prepare hydrogels .
    Poly(ethylene glycol) dithiol (Mn 3400)
  • HY-P3159A
    VPM peptide TFA

    		Biochemical Assay Reagents Others
    VPM peptide TFA is a dithiol protease-cleavable peptide cross-linker. VPM peptide TFA can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .
    VPM peptide TFA
  • HY-D1259
    NEP

    VDP-green (NEP)

    		 Fluorescent Dye Neurological Disease
    NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm). NEP has the potential for parkinsonism .
    NEP
  • HY-116748
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

    		PDI Phosphatase
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane is a small-molecule dithiol catalyst with a low thiol pKa value (8.3) and high reduction potential (-0.24 V), capable of mimicking PDI activity. It catalyzes the activation of scrambled ribonuclease A (scrambled ribonuclease A) and promotes the formation of native disulfide bonds, thereby significantly enhancing protein folding efficiency. Adding (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane to the culture medium of Saccharomyces cerevisiae can increase the secretion of exogenously expressed Schizosaccharomyces pombe acid phosphatase by more than threefold. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane holds great potential for applications in protein production and secretion research .
    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

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