Search Result

Results for "

dopamine-beta-hydroxylase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dopamine β-hydroxylase (17) Antibiotic (2) Apoptosis (2) Aryl Hydrocarbon Receptor (1) Bacterial (1) BCRP (1) Cytochrome P450 (2) Endogenous Metabolite (1) Fungal (1) Influenza Virus (2) Monoamine Oxidase (2) P-glycoprotein (1) Phosphatase (1) PKC (2) Reverse Transcriptase (2) Telomerase (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (10) Infection (6) Metabolic Disease (2) Neurological Disease (3)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Targets Recommended: Dopamine β-hydroxylase Dopamine Receptor Tryptophan Hydroxylase Dopamine Transporter Tyrosine Hydroxylase HIF/HIF Prolyl-Hydroxylase Amyloid-β TGF-β Receptor Beta-secretase β-glucuronidase TGF-beta/Smad 17β-HSD β-catenin 11β-HSD Beta-lactamase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100796

Guanoclor Vatensol	Dopamine β-hydroxylase	Cardiovascular Disease
Guanoclor is an antihypertensive compound. Guanoclor is an adrenergic neurone-blocking agent, which also interferes with noradrenaline synthesis by inhibition of the enzyme dopamine beta-hydroxylase .

HY-125796

U-14624	Dopamine β-hydroxylase	Neurological Disease
U-14624 is a potent and orally active **dopamine beta-hydroxylase** inhibitor. U-14624 suppresses the activities of aminopyrine N-demethylase, aniline hydroxylase and p-nitroanisole O-demethylase enzymes .

HY-128483

Fusaric acid	Dopamine β-hydroxylase	Infection
Fusaric acid is a potent **dopamine β-hydroxylase** inhibitor.

HY-13289A

Nepicastat hydrochloride 3 Publications Verification SYN-117 hydrochloride; RS-25560-197 hydrochloride	Dopamine β-hydroxylase	Cardiovascular Disease
Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of *dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine (IC₅₀=8.5 nM) and human (IC₅₀=9 nM) dopamine-beta-hydroxylase*. Nepicastat hydrochloride can cross the blood-brain barrier (BBB) .

HY-116158

Oosponol	Dopamine β-hydroxylase Fungal	Infection Cardiovascular Disease
Oosponol is a **dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi** .

HY-165140

Dopastin	Others	Others
Dopastin is a compound that inhibits dopamine β-hydroxylase.

HY-W204613

3-Allylphenol	Dopamine β-hydroxylase	Others
3-Allylphenol is an inhibitor of **dopamine β-hydroxylase with a K_i** value of 12 mM .

HY-13289

Nepicastat SYN117; RS-25560-197	Dopamine β-hydroxylase	Cardiovascular Disease
Nepicastat (SYN117) is a selective, potent, and orally active inhibitor of *dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC₅₀=8.5 nM) and human (IC₅₀=9 nM) dopamine-beta-hydroxylase*. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .

HY-128483R

Fusaric acid (Standard)	Dopamine β-hydroxylase	Infection
Fusaric acid (Standard) is the analytical standard of Fusaric acid. This product is intended for research and analytical applications. Fusaric acid is a potent dopamine β-hydroxylase inhibitor.

HY-156989

Butobendine	Dopamine β-hydroxylase	Cardiovascular Disease
Butobendine, a double ester of 2-aminobutanol and trimethoxybenzoic acid, is an antiarrhythmic agent . Butobendine is a noncompetitive inhibitor of **dopamine β-hydroxylase (DBH**) .

HY-13289B

(R)-Nepicastat hydrochloride (R)-SYN117 hydrochloride; (R)-RS-25560-197 hydrochloride; RS-25560-198 hydrochloride	Dopamine β-hydroxylase	Cardiovascular Disease
(R)-Nepicastat hydrochloride is the isomer of Nepicastat (HY-13289). Nepicastat (SYN117) is a selective，potent，and orally active inhibitor of *dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC₅₀=8.5 nM) and human (IC₅₀=9 nM) dopamine-beta-hydroxylase*. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .

HY-14838

Etamicastat BIA 5-453	Dopamine β-hydroxylase	Cardiovascular Disease
Etamicastat (BIA 5-453) is a potent and reversible *dopamine-β-hydroxylase* (DBH) inhibitor with an IC₅₀ value of 107 nM . Etamicastat can be used in the research of cardiovascular diseases .

HY-14838A

Etamicastat hydrochloride BIA 5-453 hydrochloride	Dopamine β-hydroxylase	Cardiovascular Disease
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent and reversible *dopamine-β-hydroxylase* (DBH) inhibitor with an IC₅₀ value of 107 nM . Etamicastat can be used in the research of cardiovascular diseases .

HY-W017113

2-Mercaptobenzothiazole	Endogenous Metabolite Aryl Hydrocarbon Receptor	Metabolic Disease
2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC₅₀ value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .

HY-126907

A32390A	Dopamine β-hydroxylase Bacterial	Infection Cardiovascular Disease Metabolic Disease
A32390A is a **dopamine β-hydroxylase inhibitor and copper chelator. A32390A can inhibit the synthesis of norepinephrine, which helps lower blood pressure in DOCA hypertensive rats. A32390A can be used in research on hypertension, bacterial** infections, and metabolic disorders .

HY-N0453

Hypericin 4 Publications Verification	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase	Infection Neurological Disease Cancer
Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), *dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450*). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

HY-148001

EWP 815	Phosphatase Dopamine β-hydroxylase	Others
EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P₂ phosphatase and Ins(1,4,5)P₃ 5-phosphatase. EWP 815 also inhibits enzyme **dopamine β-hydroxylase** activity .

HY-N0453R

Hypericin (Standard) 4 Publications Verification	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase	Infection Neurological Disease Cancer
Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), *dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450*). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

HY-106004

Zamicastat BIA 5-1058	Dopamine β-hydroxylase P-glycoprotein BCRP	Cardiovascular Disease Cancer
Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC₅₀ values of 73.8 μM and 17.0 μM, respectively . Zamicastat reduces high blood pressure .

Fusaric acid	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Dopamine β-hydroxylase
Fusaric acid is a potent **dopamine β-hydroxylase** inhibitor.

2-Mercaptobenzothiazole	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Aryl Hydrocarbon Receptor
2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC₅₀ value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .

Hypericin 4 Publications Verification	Structural Classification Natural Products Classification of Application Fields Guttiferae Source classification Phenols Polyphenols Hyperlcurn perforatum L. Plants Disease Research Fields Cancer	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase
Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), *dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450*). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

Hypericin (Standard) 4 Publications Verification	Structural Classification Natural Products Classification of Application Fields Guttiferae Source classification Phenols Hyperlcurn perforatum L. Plants Disease Research Fields Cancer	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase
Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), *dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450*). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

Oosponol	Structural Classification Monophenols Microorganisms Source classification Phenols	Dopamine β-hydroxylase Fungal
Oosponol is a **dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi** .

Fusaric acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Dopamine β-hydroxylase
Fusaric acid (Standard) is the analytical standard of Fusaric acid. This product is intended for research and analytical applications. Fusaric acid is a potent dopamine β-hydroxylase inhibitor.

Cat. No.	Compare	Product Name	Species	Source

HY-P76874

	Dopamine beta-Hydroxylase Protein, Human (HEK293, His) dopamine beta-hydroxylase; DBH; DOPBHY	Human	HEK293
	Dopamine beta-hydroxylase protein is an essential enzyme involved in the regulation of neurotransmitters. Its main function is to catalyze the hydroxylation of dopamine, converting it into norepinephrine (also known as norepinephrine). Dopamine beta-Hydroxylase Protein, Human (HEK293, His) is the recombinant human-derived Dopamine beta-Hydroxylase protein, expressed by HEK293 , with N-His labeled tag.

Compare Products

Products

Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample
Size

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

dopamine-beta-hydroxylase

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Natural
Products