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Results for "

editing

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Deaminase (2) Adrenergic Receptor (1) Biochemical Assay Reagents (2) CRISPR/Cas9 (4) DNA/RNA Synthesis (2) Liposome (2)
By Research Areas:	Cancer (4) Endocrinology (1) Infection (1) Inflammation/Immunology (2)
Oligonucleotides:	Cationic Lipids (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

MCE Kits

Recombinant Proteins

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-150279

PolQi2 1 Publications Verification	DNA/RNA Synthesis	Others
PolQi2 is a PolΘ inhibitor that targets and inhibits alt-EJ (alternative end-joining) repair by inhibiting the helicase domain at the N-terminus of PolΘ. PolQi2 enhances the precision and integration efficiency of gene editing at different loci and in various cell lines. Furthermore, the combined use of PolQi2 with DNA-PK inhibitors reduces the off-target effects of Cas9. PolQi2 can be used in gene editing research .

HY-115686

8-Azaadenosine 3 Publications Verification	Adenosine Deaminase	Inflammation/Immunology Cancer
8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. 8-Azaadenosine blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells .

HY-139306

BAMEA-O16B	Liposome	Inflammation/Immunology
BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .

HY-19334

L755507 1 Publications Verification	Adrenergic Receptor CRISPR/Cas9	Endocrinology Cancer
L755507 is a potent, selective agonist of β₃-AR with an IC₅₀ of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing .

HY-156257

UNC9512	DNA/RNA Synthesis	Cancer
UNC9512 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis .

HY-P5307

Peptide A5K INF7-A5K-TAT	Biochemical Assay Reagents	Others
Peptide A5K (INF7-A5K-TAT) is an RNP delivery peptide. Peptide A5K effectively edits T cells without substantial impact on T cell viability .

HY-145692

Cas9-IN-3	CRISPR/Cas9	Others
Cas9-IN-3 is a potent Cas9 inhibitor (IC₅₀=28 μM) .

HY-150229

306-N16B	Liposome	Cancer
306-N16B is a lipid and allows systemic codelivery of Cas9 mRNA and sgRNA. 306-N16B can transport mRNA to the pulmonaryendothelial cell. 306-N16B can be used for research of genome editing-based therapies .

HY-153138

FTT5 LLNs	Biochemical Assay Reagents	Others
FTT5 LLNs are functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing .

HY-E70220

AsCas12a Nuclease	CRISPR/Cas9	Others
AsCas12a Nuclease is a nuclease, and can specifically cutting double-stranded DNA. AsCas12a Nuclease can be used for gene edited study .

HY-145442

8-Azanebularine	Adenosine Deaminase	Others
8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC₅₀=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (K_D=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction .

HY-136251

BRD0539	CRISPR/Cas9	Infection
BRD0539 is a Streptococcus pyogenes Cas9 (SpCas9) inhibitor with an IC₅₀ of 22 μM in an in vitro DNA cleavage assay .

Cat. No.	Product Name	Type

HY-139306

BAMEA-O16B	Drug Delivery
BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .

HY-150229

306-N16B	Drug Delivery
306-N16B is a lipid and allows systemic codelivery of Cas9 mRNA and sgRNA. 306-N16B can transport mRNA to the pulmonaryendothelial cell. 306-N16B can be used for research of genome editing-based therapies .

Cat. No.	Product Name	Target	Research Area

HY-P5307

Peptide A5K INF7-A5K-TAT	Biochemical Assay Reagents	Others
Peptide A5K (INF7-A5K-TAT) is an RNP delivery peptide. Peptide A5K effectively edits T cells without substantial impact on T cell viability .

Cat. No.	Product Name

HY-KE7066

FnCas12a
FnCas12a(Cpf1), is an RNA-guided, DNA-editable recombinant endonuclease that can be used for gene editing and detection.

HY-K2028

*OptiLNP CRISPR Gene Editing* Kit (Immune Cells)**
MCE OptiLNP CRISPR Gene Editing Kit (Immune Cells) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient co-transfection of Cas9 mRNA and sgRNA during CRISPR gene editing inimmune cells.

HY-K2027

*OptiLNP CRISPR Gene Editing* Kit**
MCE OptiLNP CRISPR Gene Editing Kit is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient co-transfection of Cas9 mRNA and sgRNA during CRISPR gene editing in common cells (adherent or suspension cells).

Species:	Human (2)
Tag:	His (2) SUMO (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72080

	APOBEC3A Protein, Human (His-SUMO) A3A; ABC3A_HUMAN; APOBEC3A; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme; catalytic polypeptide like 3A; ARP3; bK150C2.1; Catalytic polypeptide like 3A; Phorbolin 1; Phorbolin-1; PHRBN; Probable DNA dC >dU editing enzyme APOBEC-3A; Probable DNA dC->dU-editing enzyme APOBEC-3A	Human	E. coli
	APOBEC3A protein is a DNA deaminase that limits the mobility of viruses, foreign DNA, and retrotransposons. APOBEC3A Protein, Human (His-SUMO) is the recombinant human-derived APOBEC3A protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P76131

	AARSD1 Protein, Human (His) Alanyl-tRNA editing protein Aarsd1; Alanyl-tRNA synthetase domain-containing protein 1; AARSD1	Human	E. coli
	AARSD1 Protein actively functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). AARSD1 Protein, Human (His) is the recombinant human-derived AARSD1 protein, expressed by E. coli , with N-His labeled tag. The total length of AARSD1 Protein, Human (His) is 350 a.a., with molecular weight of ~40 KDa.

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Cat. No.	Product Name		Classification

HY-139306

BAMEA-O16B		Cationic Lipids
BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .

HY-150229

306-N16B		Cationic Lipids
306-N16B is a lipid and allows systemic codelivery of Cas9 mRNA and sgRNA. 306-N16B can transport mRNA to the pulmonaryendothelial cell. 306-N16B can be used for research of genome editing-based therapies .

HY-153138

FTT5 LLNs		Cationic Lipids
FTT5 LLNs are functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing .

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