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human serum

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1956
    Human serum albumin
    1 Publications Verification

    HSA

    NF-κB NO Synthase Cardiovascular Disease Inflammation/Immunology Cancer
    Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ) in the vascular wall, contributing to the reduction of blood pressure .
    Human serum albumin
  • HY-NP060

    HSA-AF488

    Biochemical Assay Reagents Others
    Human Serum Albumin-AF488 is a biochemical reagent conjugated to fluorescein AF488 (Ex=488 nm; Em=496 nm). Human Serum Albumin-AF488 can be used to label or detect specific antigens, molecules or cellular structures .
    Human Serum Albumin-AF488
  • HY-NP032

    HSA-Cy5

    Fluorescent Dye Others
    Human Sermu Albumin-Cy5 is Cy5-labeled Human serum albumin (HAS, HY-P1956) .
    Human Serum Albumin-Cy5
  • HY-NP050

    HSA-AF647

    Biochemical Assay Reagents Others
    Human Serum Albumin-AF647 (HSA-AF647) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Human Serum Albumin-AF647
  • HY-P1956A

    HSA (Cell culture grade, Endotoxin<0.125 EU/mg)

    NF-κB NO Synthase Cardiovascular Disease Inflammation/Immunology
    Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ) in the vascular wall, contributing to the reduction of blood pressure .
    Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
  • HY-150097

    Biochemical Assay Reagents Others
    Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. The main physiological function of Recombinant Human Serum Albumin (rHSA) is to regulate plasma pH and maintain plasma osmotic pressure .
    Recombinant Human Serum Albumin(rHSA)
  • HY-NP027

    HSA-Cy3

    Biochemical Assay Reagents Fluorescent Dye Others
    Human Serum Albumin-Cy3 is a human serum albumin conjugated with Cy3 (Ex=554 nm; Em=568 nm). Human Serum Albumin-Cy3 can be used as a fluorescent marker to label or detect specific antigens, molecules or cell structures .
    Human Serum Albumin-Cy3
  • HY-NP054

    HSA-APC; ApC-HSA

    Biochemical Assay Reagents Others
    Human Serum Albumin-APC (HSA-APC) is human serum albumin (HSA) labeled with allophycocyanin (APC) (HY-D1815) and can be used for fluorescent labeling and tracing experiments.
    Human Serum Albumin-APC
  • HY-NP031

    HSA-AF555

    Biochemical Assay Reagents Others
    Human Serum Albumin-AF555 is an AF555 conjugated HSA (Ex=752 nM, Em=780 nm). Human Serum Albumin-AF555 can be used in the research of cell interaction .
    Human Serum Albumin-AF555
  • HY-NP029

    HSA-RBITC

    Biochemical Assay Reagents Others
    Human Sermu Albumin-RBITC (HSA-RBITC) is a kind of biological materials or organic compounds that are widely used in life science research .
    Human Serum Albumin-RBITC
  • HY-141749A

    CLPM; SR 26334

    Endogenous Metabolite Metabolic Disease
    Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum .
    Clopidogrel carboxylic acid
  • HY-P99696

    LIB003

    PCSK9 Cardiovascular Disease Metabolic Disease
    Lerodalcibep (LIB003) is a recombinant fusion protein of a PCSK9-binding domain (adnectin) and human serum albumin. Lerodalcibep is a Lipid-lowering agent. Lerodalcibep can be used for the research of hypercholesterolemia and cardiovascular diseases .
    Lerodalcibep
  • HY-P99397

    ALX 0761; M 1095

    Interleukin Related MMP Inflammation/Immunology
    Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .
    Sonelokimab
  • HY-W011297

    Arachidonic acid methyl ester

    Others Metabolic Disease
    Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
    Methyl arachidonate
  • HY-150978

    Fluorescent Dye Others
    DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
    DDAO-C6
  • HY-139248

    Others Cancer
    Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively) .
    Paclitaxel octadecanedioate
  • HY-W007894

    Endogenous Metabolite Others
    Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .
    Dimethylmalonic acid
  • HY-148002

    Others Others
    1'-Hydroxy Midazolam-β-D-glucuronide is a β-D-glucuronide that acts as a drug metabolite, human urine metabolite, and human serum metabolite .
    1'-Hydroxy Midazolam-β-D-glucuronide
  • HY-130434

    Endogenous Metabolite Cancer
    12-SAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 12-SAHSA decreases in the human serum of breast cancer .
    12-SAHSA
  • HY-117475

    Thyroid Hormone Receptor Endocrinology
    N-Acetylthyroxine is a thyroid hormone analogue. N-Acetylthyroxine weakly binds to thyroxine-binding globulin (TBG) in isolated human serum .
    N-Acetylthyroxine
  • HY-P99385

    ALX-0061

    Interleukin Related Inflammation/Immunology
    Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (Kd: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .
    Vobarilizumab
  • HY-130705A

    VD/VDR Endogenous Metabolite Metabolic Disease
    Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705) .
    Tachysterol 3
  • HY-D0022

    5-AF

    Fluorescent Dye Others
    5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .
    5-Aminofluorescein
  • HY-108877

    BMY-28142 hydrochloride

    Antibiotic Bacterial Infection
    Cefepime hydrochloride is a cephalosporin antibiotic agent. Cefepime hydrochloride has inhibitory activity against human serum paraoxonase-1 (hPON1) with an IC50 value of 21.115 mM .
    Cefepime hydrochloride
  • HY-116078

    CETP Cardiovascular Disease
    CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated transfer of cholesteryl ester in human serum with an IC50 of 2.3 nM .
    CKD-519
  • HY-108883

    Fibrinolysins, human plasma; serum tryptase, human plasma; TAL 05-00018, human plasma

    Others Inflammation/Immunology
    Plasmin, Human plasma is an important protease present in blood that degrades many plasma proteins, including fibrin clots. Plasmin can also act as a potent regulator of the immune process and can directly interact with various cell types, including monocytes, macrophages, and dendritic cells .
    Plasmin, Human plasma
  • HY-N12329

    Others Others
    Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .
    Fumonisin B4
  • HY-B0161D

    LY248686 hydrochloride

    Others Others
    (R)-Duloxetine (LY248686) Hydrochloride is a napthalenyloxy-substituted amine utilized in binding studies with human serum albumin, and unlike its enantiomer (S)-Duloxetine, it exhibits limited efficacy as a dual serotonin and norepinephrine reuptake inhibitor (SNRI).
    (R)-Duloxetine hydrochloride
  • HY-P99796

    ATN-103

    TNF Receptor Inflammation/Immunology
    Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis .
    Ozoralizumab
  • HY-P4835

    Phosphatase Others
    pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. pTH (2-34) is not as effective as pTH (1-34) .
    pTH (2-34) (human)
  • HY-108194

    Biochemical Assay Reagents Others
    CGP 46700 (Compound 49) is an orally active iron chelator, that exhibits high affinity for iron, removes iron from ferritin and human serum transferrin. CGP 46700 promotes iron excretion in a mouse iron overload model .
    CGP 46700
  • HY-118870

    Endogenous Metabolite Inflammation/Immunology Cancer
    γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency
    γ-Globulins from human blood
  • HY-W011711R

    URAT1 Metabolic Disease
    Benzarone (Standard) is the analytical standard of Benzarone. This product is intended for research and analytical applications. Benzarone (Fragivix) is a potent human uric acid transporter 1 (hURAT1) inhibitor, with an IC50 of 2.8 μM in oocyte. Benzarone could lower uric acid serum levels .
    Benzarone (Standard)
  • HY-120398

    PTHR Endocrinology
    CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC50 of 12 μM. CH5447240 exhibits good metabolic stability in human liver microsomes. CH5447240 increases serum calcium levels in rats. CH5447240 can be used in research about hypoparathyroidism .
    CH5447240
  • HY-18780
    RR6
    2 Publications Verification

    Pantetheinase Cancer
    RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively .
    RR6
  • HY-P99458

    CG 10639

    c-Fms Cancer
    Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer .
    Balugrastim
  • HY-168728

    Monoamine Oxidase Neurological Disease
    MAO-B-IN-37 (Compound 37) is a derivative of TT01001 (HY-114520), and a selective inhibitor for monoamine oxidase B (MAO-B) with an IC50 of 270 nM. MAO-B-IN-37 exhibits good metabolic stability in mice microsomes and good affinity with human serum albumin .
    MAO-B-IN-37
  • HY-117909

    RXDX-107

    Apoptosis Cancer
    CEP-40125 (RXDX-107) is a modified form of Bendamustine (HY-13567), a DNA cross-linking agent that may cause DNA damage and cell apoptosis. CEP-40125 (RXDX-107) is formed by encapsulating the alkyl ester form of Bendamustine in human serum albumin .
    CEP-40125
  • HY-W011297S3

    Arachidonic acid methyl ester-13C5

    Isotope-Labeled Compounds Others Metabolic Disease
    Methyl arachidonate- 13C5 (Arachidonic acid methyl ester- 13C5) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
    Methyl arachidonate-13C5
  • HY-155305

    Cholinesterase (ChE) Beta-secretase GABA Receptor Neurological Disease
    BuChE-IN-9 (compound 22a) is a potent equine serum-derived BuChE (eqBuChE) inhibitor with an IC50 of 173 nM. BuChE-IN-9 also inhibits human BACE1, Aβ aggregation, mouse GABA transporter 1 (mGAT1) and mGAT4. BuChE-IN-9 has significant antiamnesic properties .
    BuChE-IN-9
  • HY-W011297S2

    Arachidonic acid methyl ester-13C4

    Isotope-Labeled Compounds Others Metabolic Disease
    Methyl arachidonate- 13C4 (Arachidonic acid methyl ester- 13C4) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
    Methyl arachidonate-13C4
  • HY-W011711

    Fragivix

    URAT1 Oxidative Phosphorylation Apoptosis Metabolic Disease
    Benzarone (Fragivix) is an oral inhibitor of human urate transporter 1 (hURAT1) with an IC50 value of 2.8 μM, and it also acts as an uncoupler of oxidative phosphorylation. Benzarone can cause liver damage and promote cell apoptosis and necrosis. Benzarone can be used to lower serum uric acid levels and for research in vascular diseases .
    Benzarone
  • HY-113777

    22-Hydroxy Docosahexaenoic acid; 22-OH DHA

    Cytochrome P450 Metabolic Disease
    22-HDHA (22-Hydroxy Docosahexaenoic acid) is an oxidation product of docosahexaenoic acid. In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
    22-HDHA
  • HY-112714A

    BMS-955176 oxalate

    HIV Infection
    GSK3532795 oxalate is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .
    GSK3532795 oxalate
  • HY-112714B

    BMS-955176 hydrochloride

    HIV Infection
    GSK3532795 hydrochloride is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .
    GSK3532795 hydrochloride
  • HY-146035

    Cholinesterase (ChE) Histamine Receptor Neurological Disease
    AChE-IN-14 (compound 5) is a potent cholinesterase inhibitor with IC50s of 0.46 , 0.48, and 0.44 μM for electric eel acetylcholinesterase (eeAChE), human recombinant acetylcholinesterase (hAChE), and equine serum butyrylcholinesterase (eqBuChE), respectively. AChE-IN-14 exhibits high affinity toward human H3 receptor (H3R; Ki= 159.8 nM). AChE-IN-14 can be used for the research of Alzheimer’s disease .
    AChE-IN-14
  • HY-13402
    Varespladib
    5 Publications Verification

    LY315920

    Phospholipase Inflammation/Immunology
    Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .
    Varespladib
  • HY-112714

    BMS-955176

    HIV Infection
    GSK3532795 (BMS-955176) is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .
    GSK3532795
  • HY-13402A
    Varespladib sodium
    5 Publications Verification

    LY315920 sodium

    Phospholipase Inflammation/Immunology
    Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .
    Varespladib sodium
  • HY-N2252

    (+)-Licarin A

    TNF Receptor Prostaglandin Receptor COX Neurological Disease Metabolic Disease Inflammation/Immunology
    Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .
    Licarin A

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