Search Result
Results for "
ionizable cationic lipid
" in MedChemExpress (MCE) Product Catalog:
14
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-145739
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-
-
- HY-W590532
-
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Liposome
|
Others
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306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
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-
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- HY-112757
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DLinDMA
1 Publications Verification
|
Liposome
|
Others
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DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
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-
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- HY-153372
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Liposome
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Others
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93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
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-
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- HY-160553
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Liposome
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Others
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9322-O16B, an ionizable cationic lipid, is used for LNP generation .
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-
-
- HY-159709
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|
Liposome
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Others
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VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .
|
-
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- HY-160908
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Liposome
|
Others
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Lipid 88 is an ionizable cationic lipid. Lipid 88 can be used to synthesize lipid nanoparticles and deliver mRNA .
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-
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- HY-159735
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Liposome
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Others
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Lipid 23 is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNP). Lipid 23 can be used for mRNA delivery .
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-
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- HY-158796
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Liposome
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Others
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L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles .
|
-
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- HY-159725
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|
Liposome
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Others
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BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs) .
|
-
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- HY-156985
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|
Isotope-Labeled Compounds
Liposome
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Others
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Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89, and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
|
-
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- HY-149156
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|
Liposome
|
Cancer
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Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
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-
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- HY-W590548
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|
Liposome
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Others
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ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
|
-
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- HY-112251
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D-Lin-MC3-DMA
Maximum Cited Publications
71 Publications Verification
|
Liposome
|
Cancer
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
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- HY-W590531
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-
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- HY-112251A
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|
Liposome
|
Cancer
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D-Lin-MC3-DMA Excipient, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
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- HY-151511
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|
Liposome
|
Cancer
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
-
- HY-159726
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|
Liposome
|
Others
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C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .
|
-
-
- HY-W598178
-
|
Liposome
|
Others
|
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
|
-
-
- HY-W590678
-
|
Liposome
|
Others
|
SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
|
-
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- HY-156936
-
|
Liposome
|
Others
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RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
|
-
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- HY-153737
-
|
Liposome
|
Others
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
-
- HY-142654
-
|
Liposome
|
Others
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
-
- HY-W590681
-
|
Liposome
|
Others
|
113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
-
- HY-W590679
-
|
Liposome
|
Others
|
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
-
- HY-W800849
-
|
Liposome
|
Cancer
|
BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
|
-
-
- HY-151512
-
-
-
- HY-160852
-
|
Liposome
|
Inflammation/Immunology
|
YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines .
|
-
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- HY-160552
-
|
Liposome
|
Others
|
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
|
-
-
- HY-112251S
-
|
Isotope-Labeled Compounds
|
Others
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
|
-
-
- HY-145405
-
|
Liposome
|
Others
|
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
|
-
-
- HY-159700
-
|
Liposome
|
Infection
|
AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
|
-
-
- HY-157252
-
|
Liposome
|
Cancer
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
-
- HY-130751
-
|
Liposome
|
Inflammation/Immunology
|
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-145739
-
-
- HY-W590532
-
|
Drug Delivery
|
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
|
-
- HY-112757
-
DLinDMA
1 Publications Verification
|
Drug Delivery
|
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
|
-
- HY-153372
-
|
Drug Delivery
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
71 Publications Verification
|
Drug Delivery
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
- HY-W590678
-
|
Drug Delivery
|
SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
|
-
- HY-153737
-
|
Drug Delivery
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
- HY-142654
-
|
Drug Delivery
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
- HY-149156
-
|
Drug Delivery
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
- HY-151511
-
|
Drug Delivery
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
- HY-151512
-
|
Drug Delivery
|
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
|
-
- HY-145405
-
|
Drug Delivery
|
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
|
-
- HY-157252
-
|
Drug Delivery
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-130751
-
|
Drug Delivery
|
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
|
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-112251S
-
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-145739
-
-
- HY-W590532
-
|
|
Cationic Lipids
|
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
|
-
- HY-112757
-
DLinDMA
1 Publications Verification
|
|
Cationic Lipids
|
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
|
-
- HY-153372
-
|
|
Cationic Lipids
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
- HY-160553
-
|
|
Cationic Lipids
|
9322-O16B, an ionizable cationic lipid, is used for LNP generation .
|
-
- HY-159709
-
|
|
Cationic Lipids
|
VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .
|
-
- HY-160908
-
|
|
Cationic Lipids
|
Lipid 88 is an ionizable cationic lipid. Lipid 88 can be used to synthesize lipid nanoparticles and deliver mRNA .
|
-
- HY-158796
-
|
|
Cationic Lipids
|
L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles .
|
-
- HY-159725
-
|
|
Cationic Lipids
|
BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs) .
|
-
- HY-156985
-
|
|
Cationic Lipids
|
Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89, and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
|
-
- HY-149156
-
|
|
Cationic Lipids
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
- HY-W590548
-
|
|
Cationic Lipids
|
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
|
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
71 Publications Verification
|
|
Cationic Lipids
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
- HY-W590531
-
|
|
Cationic Lipids
|
80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .
|
-
- HY-112251A
-
-
- HY-151511
-
|
|
Cationic Lipids
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
- HY-159726
-
|
|
Cationic Lipids
|
C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .
|
-
- HY-W590678
-
|
|
Cationic Lipids
|
SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
|
-
- HY-156936
-
|
|
Cationic Lipids
|
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
|
-
- HY-153737
-
|
|
Cationic Lipids
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
- HY-142654
-
|
|
Cationic Lipids
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
- HY-W590679
-
|
|
Cationic Lipids
|
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-W800849
-
|
|
Cationic Lipids
|
BP Lipid 315 is a cationic ionizable lipid ALC-0315 analogue featuring a Boc-protected primary amine, a central tertiary amine, and two ester tails located at the C8 position relative to the amine. One of these esters features a symmetrical branched C17 tail, while the other is an asymmetric C11 tail.
|
-
- HY-151512
-
|
|
Cationic Lipids
|
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
|
-
- HY-160552
-
|
|
Cationic Lipids
|
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
|
-
- HY-145405
-
|
|
Cationic Lipids
|
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
|
-
- HY-159700
-
|
|
Cationic Lipids
|
AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
|
-
- HY-157252
-
|
|
Cationic Lipids
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-130751
-
|
|
Cationic Lipids
|
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
|
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