Search Result
Results for "
isopropyl ester
" in MedChemExpress (MCE) Product Catalog:
11
Biochemical Assay Reagents
13
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-109545
-
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Unoprostone isopropyl ester; UF-021
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Potassium Channel
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Others
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Isopropyl unoprostone (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca 2+-activated K + (BK) channels activator. Isopropyl unoprostone has antiglaucoma effects, lowering intraocular pressure (IOP) by increasing aqueous humour outflow. Isopropyl unoprostone can improve retinal sensitivity and the protection of central retinal sensitivity .
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-
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- HY-125383
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-
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- HY-W415007
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Stearic acid,isopropyl ester
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Others
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Metabolic Disease
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Isopropyl stearate (Stearic acid,isopropyl ester) is an ester product.
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-
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- HY-157002
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PGE2 isopropyl ester
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Others
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Others
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Prostaglandin E2 isopropyl ester (PGE2 isopropyl ester) is the precursor of PGE2.
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-
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- HY-124190R
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Others
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Others
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Isopropyl myristate (Standard) is the analytical standard of Isopropyl myristate. This product is intended for research and analytical applications. Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired .
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- HY-130406
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Others
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Infection
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Benthiavalicarb isopropyl is a fungicide with specific activity against downy mildew and blight. Benthiavalicarb isopropyl is evaluated for use where necessary to control a serious threat to plant health that cannot be treated by other methods, including non-chemical methods. The use of Benthiavalicarb isopropyl can be considered representative of field applications in potatoes. Environmental and human exposures of Benthiavalicarb isopropyl are considered to be negligible .
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-
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- HY-139386
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15(S)-Flu-Ipr
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Others
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Others
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15β-Travoprost (15(S)-Flu-Ipr) is an enantiomer of Travoprost (HY-B0584). Travoprost, an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist .
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- HY-100571
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-
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- HY-Z0291
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isopropyl L-alaninate; L-Alanine 2-propyl ester; L-Alanine isopropyl ester; O-isopropyl-L-alanine
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Amino Acid Derivatives
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Others
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L-Alanine isopropyl ester is an alanine derivative .
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-
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- HY-143519S
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-
-
- HY-W012578S
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-
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- HY-W142667S
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-
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- HY-W016491R
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Bacterial
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Infection
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Isopropyl 4-hydroxybenzoate (Standard) is the analytical standard of Isopropyl 4-hydroxybenzoate. This product is intended for research and analytical applications. Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
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- HY-W127420
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Linoleic acid isopropyl ester
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Biochemical Assay Reagents
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Others
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Isopropyl Linoleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-111406
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DE-117
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Prostaglandin Receptor
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Inflammation/Immunology
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Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration, and Omidenepag is a highly selective EP2 receptor agonist. Omidenepag isopropyl shows only weak affinity for EP1, EP2, and FP receptors. Omidenepag isopropyl is under development for the treatment of glaucoma as an intraocular pressure (IOP)-lowering agent.
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- HY-W127422
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N-Capric acid isopropyl ester
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Biochemical Assay Reagents
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Others
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Isopropyl Decanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-142784S
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-
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- HY-W017195
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Propan-2-yl benzoate
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Biochemical Assay Reagents
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Others
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Isopropyl benzoate is a class of esters consisting of a benzene ring and an isopropyl group attached to a carboxylic acid group. Isopropyl benzoate can be used as an inducer to biosynthesize phloroglucinol in E. coli .
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- HY-Z0711
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-
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- HY-W002062
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Biochemical Assay Reagents
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Others
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(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-19998
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- HY-W016491
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isopropylparaben
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Bacterial
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Infection
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Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
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- HY-131253
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Drug Metabolite
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Others
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Febuxostat isopropyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM .
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- HY-N4203
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Fungal
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Infection
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Isopropyl ferulate, isolated from Notopterygium incisum, is used in the reduction of pharmaceuticals, preparation of antifungal agents, cosmetics and as antioxidant agent and so forth .
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- HY-19923
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-
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- HY-W127510
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Octanoicacidisopropylester
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Biochemical Assay Reagents
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Others
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Isopropyl n-Octanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W130442
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Others
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Inflammation/Immunology
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N-Isopropyl-N'-phenyl-p-phenylenediamine is an antioxidant used in rubber manufacturing to reduce the detrimental effect of oxygen. N-Isopropyl-N'-phenyl-p-phenylenediamine can cause contact allergy .
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-
-
- HY-106037
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Others
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Others
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PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation .
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- HY-B0584
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Fluprostenol isopropyl ester; AL6221; Flu-Ipr
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Prostaglandin Receptor
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Endocrinology
|
|
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
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- HY-138455
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PROTAC Linkers
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Cancer
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Bis-isopropyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W016491S
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- HY-154428
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Nucleoside Antimetabolite/Analog
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Cancer
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2’-Deoxy-N2-isopropyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W145651
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Biochemical Assay Reagents
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Others
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Isopropyl β-D-thioglucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-116161
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Others
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Cardiovascular Disease
Others
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15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
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- HY-129462
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IPETC
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Others
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Others
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O-Isopropyl ethylthiocarbamate can be used as an environmentally friendly alternative in combination with pyrogallic acid (PGA) to replace the lime-xanthate flotation process traditionally used for chalcopyrite-molybdenite (ccp-mlb) ores .
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- HY-148909
-
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IDEFP
|
Cannabinoid Receptor
FAAH
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Neurological Disease
|
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Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester that antagonizes the central cannabinoid receptor (CB1) and inhibits FAAH with similar potencies (IC50 = 2 nM) .
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- HY-50911
-
|
FXR-450; XL335; WAY-362450
|
FXR
Autophagy
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Metabolic Disease
Cancer
|
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Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM .
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-
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- HY-W011426
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Propan-2-yl hexadecanoate
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Biochemical Assay Reagents
Liposome
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Others
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Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-W012578S2
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- HY-59121
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- HY-156438
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NOD-like Receptor (NLR)
Interleukin Related
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Neurological Disease
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NT-0796 is an orally active, selective and CNS-penetrant NLRP3 inflammasome inhibitor. NT-0796 inhibits IL-1β release in human PBMC cells with an IC50 value of 0.32 nM. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 reverses high fat diet-induced obesity, systemic inflammation and astrogliosis in the diet-induced obesity mouse model. NT-0796 is promising for research of neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and amyotrophic lateral sclerosis .
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- HY-W023443S
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2-Methyl-5-(1-methylethyl)pyrazine-d3
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Isotope-Labeled Compounds
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Others
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2-Isopropyl-5-methylpyrazine-d3 is deuterated labeled 5-Butyldihydrofuran-2(3H)-one.
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-
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- HY-B0584R
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Fluprostenol isopropyl ester(Standard); AL6221(Standard); Flu-Ipr (Standard)
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Prostaglandin Receptor
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Endocrinology
|
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Travoprost (Standard) is the analytical standard of Travoprost. This product is intended for research and analytical applications. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
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- HY-N10771
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Others
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Others
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(R)-2-Isopropyl-8,8,8a-trimethyl-6,7,8,8a-tetrahydrophenanthrene-3,4-diol (compound 48) is a catechol compound. (R)-2-Isopropyl-8,8,8a-trimethyl-6,7,8,8a-tetrahydrophenanthrene-3,4-diol involves in bioinspired synthesis of rearranged abietane diterpenes, related to pygmaeocins .
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- HY-W012578S1
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- HY-116617
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15-Keto Fluprostenol isopropyl ester
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Drug Metabolite
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Others
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15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes .
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- HY-158550
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- HY-124200
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Prostaglandin Receptor
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Endocrinology
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AL 8810 (Item No. 16735) is an 11β-fluoro analog of prostaglandin F2α which acts as a potent and selective antagonist at the FP receptor. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost (HY-B0577) and Travoprost (HY-B0584).
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- HY-116161A
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Prostaglandin Receptor
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Endocrinology
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17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost.2 This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative is examined for IOP-lowering activity during the development of latanoprost.4 At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester is the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative is also significantly more irritating to the eye than latanoprost.
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- HY-B0584A
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5,6-trans-Fluprostenol isopropyl ester; 5,6-trans-AL6221; 5,6-trans-Flu-Ipr
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Others
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Endocrinology
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5,6-trans-Travoprost is the isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
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- HY-114385
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13,14-epoxy Fluprostenol isopropyl ester
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Others
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Others
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13,14-epoxy Travoprost (13,14-epoxy Fluprostenol isopropyl ester) is a mixture of diastereomeric epoxides generated during production of Travoprost (HY-B0584). Travoprost is a selective agonist for prostaglandin F receptor, which exhibits an ocular hypotensive efficacy .
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- HY-W777089
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Biochemical Assay Reagents
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Others
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Benzyl 5-amino-5-deoxy-2,3-O-isopropyl-α-D-mannofuranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W099862S1
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- HY-W012932S
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- HY-N10703
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Others
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Others
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2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione is a C20 -norabietane diterpenoid with anti-inflammatory activity. 2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione can be isolated from sage leaves .
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- HY-W012927S
-
-
- HY-W740764
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-
- HY-W717530
-
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7-isopropyl-1-methylphenanthrene
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Others
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Others
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Retene is widely present in modern and ancient sediments, and can be extracted from fir forest soils, humus coal, continental petroleum source rocks, and deep-sea sediments. Retene can be toxic when exposed to light, and this light-induced toxicity can have lethal and sublethal effects on aquatic organisms. Retene can be used as a model compound to study the interaction between environmental pollutants and ultraviolet rays .
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- HY-15921
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IPTG
Maximum Cited Publications
9 Publications Verification
isopropyl β-D-thiogalactoside
|
Biochemical Assay Reagents
|
Others
|
|
IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator.
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- HY-101304
-
|
S-isopropyl ITU; IPTU
|
NO Synthase
|
Neurological Disease
|
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S-Isopropylisothiourea (IPTU) hydrobromide is a potent and selective inhibitor of Nitric Oxide Synthase (NOS). S-Isopropylisothiourea (IPTU) hydrobromide is used in the research for hemorrhagic shock .
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- HY-118294
-
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16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor PGF2α isopropyl ester
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Others
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Cardiovascular Disease
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15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments .
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- HY-W004356S
-
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(Rac)-GS-7340-d5
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Isotope-Labeled Compounds
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Others
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(2R)-Isopropyl 2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate-d5 is the deuterium labeled (2R)-isopropyl 2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate [
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- HY-131233
-
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Remdesivir isopropyl ester analog
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Antibiotic
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Infection
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Anti-virus agent 1 (compound 4i), a phosphoramidate proagent of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV) .
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- HY-17642
-
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UR-7276
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Prostaglandin Receptor
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Endocrinology
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Omidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2 .
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- HY-152653
-
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Nucleoside Antimetabolite/Analog
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Cancer
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N6-iso-Propyl-2’-O-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-116679
-
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17-Trifluoromethylphenyl trinor PGF2α
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Prostaglandin Receptor
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Endocrinology
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A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists.4 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic, with a potency equal to or greater than fluprostenol and cloprostenol.
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- HY-113778
-
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15-keto-17-phenyl trinor PGF2α
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Prostaglandin Receptor
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Endocrinology
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|
Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.1 Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compound, 15-keto PGs still retain the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye.2 15-keto Latanoprost (15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester) is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type PGs; for example, PGF2α will produce this degree of miosis at a dose of less than 1 μg/eye.
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| Cat. No. |
Product Name |
Type |
-
- HY-W002062
-
|
|
Biochemical Assay Reagents
|
|
(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W011426
-
|
Propan-2-yl hexadecanoate
|
Drug Delivery
|
|
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-W016491R
-
|
|
Biochemical Assay Reagents
|
|
Isopropyl 4-hydroxybenzoate (Standard) is the analytical standard of Isopropyl 4-hydroxybenzoate. This product is intended for research and analytical applications. Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
|
-
- HY-W127420
-
|
Linoleic acid isopropyl ester
|
Biochemical Assay Reagents
|
|
Isopropyl Linoleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127422
-
|
N-Capric acid isopropyl ester
|
Biochemical Assay Reagents
|
|
Isopropyl Decanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W017195
-
|
Propan-2-yl benzoate
|
Biochemical Assay Reagents
|
|
Isopropyl benzoate is a class of esters consisting of a benzene ring and an isopropyl group attached to a carboxylic acid group. Isopropyl benzoate can be used as an inducer to biosynthesize phloroglucinol in E. coli .
|
-
- HY-W016491
-
|
isopropylparaben
|
Biochemical Assay Reagents
|
|
Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
|
-
- HY-W127510
-
|
Octanoicacidisopropylester
|
Biochemical Assay Reagents
|
|
Isopropyl n-Octanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W145651
-
|
|
Biochemical Assay Reagents
|
|
Isopropyl β-D-thioglucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W777089
-
|
|
Carbohydrates
|
|
Benzyl 5-amino-5-deoxy-2,3-O-isopropyl-α-D-mannofuranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-15921
-
|
isopropyl β-D-thiogalactoside
|
Carbohydrates
|
|
IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-Z0711
-
-
- HY-59121
-
-
- HY-59121A
-
|
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Peptides
|
Infection
|
|
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities .
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- HY-Z0291
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isopropyl L-alaninate; L-Alanine 2-propyl ester; L-Alanine isopropyl ester; O-isopropyl-L-alanine
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Amino Acid Derivatives
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Others
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L-Alanine isopropyl ester is an alanine derivative .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N4203
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- HY-116161
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Cardiovascular Disease
Classification of Application Fields
Disease Research Fields
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Others
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15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
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- HY-N10771
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Structural Classification
Flavonoids
Terpenoids
Gramineae
Source classification
Morus nigra Linn.
Diterpenoids
Plants
Moraceae
Other Flavonoids
Saccharum officinarum
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Others
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(R)-2-Isopropyl-8,8,8a-trimethyl-6,7,8,8a-tetrahydrophenanthrene-3,4-diol (compound 48) is a catechol compound. (R)-2-Isopropyl-8,8,8a-trimethyl-6,7,8,8a-tetrahydrophenanthrene-3,4-diol involves in bioinspired synthesis of rearranged abietane diterpenes, related to pygmaeocins .
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- HY-N10703
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-143519S
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Isopropyl phenyl-d7 is the deuterium labeled Isopropyl phenyl[1].
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- HY-W012578S
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2-Isopropyl-3-methoxypyrazine-d3 is the deuterium labeled 2-Isopropyl-3-methoxypyrazine[1].
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- HY-W142667S
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1-Isopropyl-4-nitrobenzene-d4 is the deuterium labeled 1-Isopropyl-4-nitrobenzene[1].
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- HY-142784S
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Isopropyl diphenyl phosphate-d7 is the deuterium labeled Isopropyl diphenyl phosphate[1].
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- HY-W016491S
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Isopropyl 4-hydroxybenzoate-d4 is the deuterium labeled Isopropyl 4-hydroxybenzoate[1].
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- HY-W012578S2
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2-Isopropyl-3-methoxypyrazine-d7 is deuterated labeled 2-Methylfuran-3-thiol.
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- HY-W023443S
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2-Isopropyl-5-methylpyrazine-d3 is deuterated labeled 5-Butyldihydrofuran-2(3H)-one.
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- HY-W012578S1
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2-Isopropyl-3-methoxypyrazine- 13C3 is 13C labeled Octan-2-one.
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- HY-W099862S1
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2-Ethylphenol-d2 is deuterated labeled 2-Isopropyl-5-methylpyrazine.
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- HY-W012932S
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2,4-Dimethylthiazole- 13C3 is 13C labeled 2-Isopropyl-3-methoxypyrazine.
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- HY-W012927S
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4-Hydroxy-5-methylfuran-3(2H)-one-d3 is deuterated labeled 2-Isopropyl-3-methoxypyrazine.
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- HY-W740764
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propan-2-yl-d7 4-hydroxybenzoate is the deuterium labeled propan-2-yl 4-hydroxybenzoate .
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- HY-W004356S
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(2R)-Isopropyl 2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate-d5 is the deuterium labeled (2R)-isopropyl 2-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate [
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| Cat. No. |
Product Name |
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Classification |
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- HY-124190
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Solvents
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Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired .
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- HY-W011426
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Propan-2-yl hexadecanoate
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Solvents
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Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-154428
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Nucleosides and their Analogs
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2’-Deoxy-N2-isopropyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-152653
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Nucleosides and their Analogs
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N6-iso-Propyl-2’-O-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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