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Results for "

lymphotoxin α

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

2

Inhibitory Antibodies

5

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Area
  • HY-P990034
    Pateclizumab

    MLTA3698A; RG7415; PRO283698

    		 Inhibitory Antibodies Inflammation/Immunology
    Pateclizumab (MLTA3698A) is a humanized antibody against lymphotoxin α (LTα), a transiently expressed cytokine on activated B and T cells (Th1, Th17), which are implicated in rheumatoid arthritis (RA) pathogenesis .
  • HY-P99459
    Baminercept

    BG 9924; TT-47

    		 TNF Receptor Inflammation/Immunology
    Baminercept (BG 9924) is an anti-lymphotoxin β receptor (LTβR) IgG fusion protein (LTβR-Ig). Baminercept selectively binds to the LTβR ligand LTα/β heterotrimer and LIGHT, block the LTβR signaling pathway, and inhibits the expression of chemokines such as CXCL13. Baminercept also regulates peripheral blood B cell and T cell subsets, reduces the transcription of IFN-induced genes. Thereby Baminercept inhibits the formation of high endothelial venules and reticular structures in lymphoid tissues, and affects immune cell migration. Baminercept can be used for the study of autoimmune diseases such as primary Sj?gren's syndrome (pSS) and rheumatoid arthritis (RA) .

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