Search Result
Results for "
orchard fire blight
" in MedChemExpress (MCE) Product Catalog:
2
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W744966
-
|
Antibiotic
|
Infection
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Mandipropamid displays outstanding activity against late blight diseases of potato and tomato, combined with excellent efficacy on downy mildew diseases of grape and cucumber .
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-
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- HY-119540
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Fungal
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Infection
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Furametpyr is a fungicide used to control rice sheath blight. Furametpyr exhibits a wide variety of metabolites in rats, through recombinant human cytochrome P450 .
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-
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- HY-133528
-
-
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- HY-W744966R
-
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Antibiotic
|
Infection
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Mandipropamid (Standard) is the analytical standard of Mandipropamid. This product is intended for research and analytical applications. Mandipropamid displays outstanding activity against late blight diseases of potato and tomato, combined with excellent efficacy on downy mildew diseases of grape and cucumber .
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- HY-163891
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Fungal
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Infection
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Antifungal agent 107 (compound b24) is an OSBP inhibitor with antifungal activity. Antifungal agent 107 can be used to control cucumber downy mildew and potato late blight in greenhouse .
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-
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- HY-W714076
-
|
Fungal
|
Infection
Inflammation/Immunology
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Ametoctradin is a potent Qo site inhibitor of bc1 complex in mitochondrial respiration. Ametoctradin is a highly selective and effective Oomycete-specific fungicide that can be used against late blight and downy mildews .
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- HY-155644
-
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Bacterial
Reactive Oxygen Species
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Infection
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ROS inducer 1 (compound I29) is a fungicide, with EC50 against Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo), and Pseudomonas syringae pv. actinidiae (Psa) of 5.73, 6.62 and 9.05 μg/mL. ROS inducer 1 can effectively induce the production of ROS in Xanthomonas cells and inhibit rice bacterial blight. ROS inducer 1 has the potential to study bacterial infection in crops .
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- HY-W714076R
-
|
Fungal
|
Infection
Inflammation/Immunology
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Ametoctradin (Standard) is the analytical standard of Ametoctradin. This product is intended for research and analytical applications. Ametoctradin is a potent Qo site inhibitor of bc1 complex in mitochondrial respiration. Ametoctradin is a highly selective and effective Oomycete-specific fungicide that can be used against late blight and downy mildews .
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-
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- HY-10351A
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NAD-299 hydrochloride
|
5-HT Receptor
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Neurological Disease
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Robalzotan hydrochloride (NAD-299 hydrochloride) is a potent and selective 5-Hydroxytryptamine 1A (5-HT1A) inhibitor. Robalzotan hydrochloride increases the firing rate of 5-HT cells. Robalzotan hydrochloride induces 5-HT1A receptor occupancy. Robalzotan hydrochloride has the potential for the research of a cholinergic deficit in the central -nervous system .
|
-
-
- HY-10351
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NAD-299
|
5-HT Receptor
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Neurological Disease
|
Robalzotan (NAD-299) is a potent and selective 5-Hydroxytryptamine 1A (5-HT1A) inhibitor. Robalzotan increases the firing rate of 5-HT cells. Robalzotan induces 5-HT1A receptor occupancy. Robalzotan has the potential for the research of a cholinergic deficit in the central -nervous system .
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-
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- HY-121248
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AC217300
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Mitochondrial Metabolism
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Infection
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Hydramethylnon (AC217300) is an amidinohydrazone insecticide. Hydramethylnon's mechanism of action is through inhibition of mitochondrial respiration by inhibiting the electron transport chain at the cytochrome b-c1 complex. Hydramethylnon can be used to eliminate red imported fire ants, cockroaches, and other insects .
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- HY-N12498
-
|
Antibiotic
Bacterial
|
Infection
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Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. .
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- HY-139161
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Fungal
|
Infection
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Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases .
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- HY-10955
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Calcium Channel
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Neurological Disease
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TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy .
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- HY-139161R
-
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Fungal
|
Infection
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Penflufen (Standard) is the analytical standard of Penflufen. This product is intended for research and analytical applications. Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases .
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- HY-B2048
-
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Fungal
|
Infection
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Pencycuron is a benzoylurea fungicide. Pencycuron kills fungi by inhibiting the synthesis of fungal cell walls.Pencycuron can be used in research on the control of fungal diseases on crops, such as sheath blight, powdery mildew and late blight .
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-
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- HY-119558
-
|
Endogenous Metabolite
|
Others
|
Bromacil serves as the active ingredient in Krovar, a commercially available pesticide extensively utilized for weed management in citrus orchards.
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-
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- HY-B2048R
-
|
Fungal
|
Infection
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Pencycuron (Standard) is the analytical standard of Pencycuron. This product is intended for research and analytical applications. Pencycuron is a benzoylurea fungicide. Pencycuron kills fungi by inhibiting the synthesis of fungal cell walls.Pencycuron can be used in research on the control of fungal diseases on crops, such as sheath blight, powdery mildew and late blight .
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- HY-125928
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|
Sodium Channel
|
Neurological Disease
|
AA43279 is an in gamma-aminobutyric acid (GABA) fast-firing interneurons located activator for Nav1.1 channel (SCN1A) with an EC50 of 9.5 μM. AA43279 enhances specific neuronal firing activity in vitro, and exhibits anticonvulsant activity in rat MEST model .
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- HY-119558R
-
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Endogenous Metabolite
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Others
|
Bromacil (Standard) is the analytical standard of Bromacil. This product is intended for research and analytical applications. Bromacil serves as the active ingredient in Krovar, a commercially available pesticide extensively utilized for weed management in citrus orchards.
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- HY-78036
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Citronic acid; Methylfumaric acid
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Endogenous Metabolite
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Others
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Mesaconic acid is an active product that can be extracted from Saxifraga stolonifera. Mesaconic acid is used as a fire retardant and is a competitive inhibitor of fumarate reduction .
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- HY-155096
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Bacterial
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Infection
|
Antibacterial agent 149 (Compd 3j) is a laccase inhibitor with high fungicidal activity and can be used in the study of rice sheath blight .
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-
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- HY-103474
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(-)-Bicuculline methiodide; l-Bicuculline methiodide
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GABA Receptor
|
Neurological Disease
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Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current .
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- HY-B1953
-
|
Parasite
DNA Stain
|
Infection
|
Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables . Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions .
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- HY-111968
-
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Fungal
|
Infection
|
Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice .
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-
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- HY-119657
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Bacterial
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Others
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Cellocidin is an agricultural antibiotic with preventive effects against rice bacterial leaf blight and is thought to work by inhibiting the α-ketoglutarate-succinate system in Xanthomonas sp.
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-
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- HY-N4250
-
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Others
|
Infection
|
Periplocoside N, a pregnane glycoside isolated from root powder of Periploca sepium, possesses insecticidal activities against the red imported fire ant .
|
-
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- HY-Y0978S2
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N-tert-Butoxycarbonyl-2-aminoacetic acid-2-13C; NSC 127669-2-13C
|
Isotope-Labeled Compounds
Androgen Receptor
|
Endocrinology
|
Boc-Glycine-2- 13C is a 13C-labeled Linuron. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive a
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- HY-B2053
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Bacterial
|
Infection
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Tolclofos-methyl is a broad-spectrum aromatic hydrocarbon fungicide that is used as a see treatment for protection against soil-borne and seed borne fungal pathogens that caused seed decay and seedling blights.
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-
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- HY-B1657A
-
|
Sodium Channel
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Neurological Disease
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Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
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-
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- HY-B1866
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|
Androgen Receptor
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Endocrinology
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Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor .
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-
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- HY-B1953R
-
|
Parasite
DNA Stain
|
Infection
|
Thiacloprid (Standard) is the analytical standard of Thiacloprid. This product is intended for research and analytical applications. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables . Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions .
|
-
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- HY-111968R
-
|
Fungal
|
Infection
|
Orysastrobin (Standard) is the analytical standard of Orysastrobin. This product is intended for research and analytical applications. Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice .
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-
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- HY-118461
-
|
Dopamine Receptor
|
Neurological Disease
|
PD 120697 is an orally active dopamine (DA) agonist. PD 120697 inhibits striatal DA synthesis, DA neuronal firing, spontaneous locomotor activity, and reverses Reserpine (HY-N0480)-induced depression .
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-
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- HY-119990
-
|
Others
|
Neurological Disease
Inflammation/Immunology
|
Fotocaine is a photochromic blocker of voltage-gated ion channels. Fotocaine is readily taken up by neurons in brain slices and enables optical control of action potential firing by switching between 350 and 450 nm light. Fotocaine can be used in analgesia research .
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- HY-D1517
-
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Fluorescent Dye
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Others
|
FM 2-10 is a fluorescent dye. FM 2-10 is a less hydrophobic version of FM 1-43 (HY-D1434). FM 2-10 can be used for identifying actively firing neurons and investigating the mechanisms of activity-dependent vesicle cycling .
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- HY-118706
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Dopamine Receptor
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Neurological Disease
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PD 118440 is an orally active dopamine (DA) agonist. PD 118440 has significant central nervous system effects, including inhibition of striatal DA synthesis, suppression of DA neuron firing, and reversal of Reserpine (HY-N0480)-induced depression in rats .
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- HY-B1657AR
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Sodium Channel
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Neurological Disease
|
Fosphenytoin (disodium) (Standard) is the analytical standard of Fosphenytoin (disodium). This product is intended for research and analytical applications. Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
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- HY-B1866R
-
|
Androgen Receptor
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Endocrinology
|
Linuron (Standard) is the analytical standard of Linuron. This product is intended for research and analytical applications. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor .
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- HY-100539
-
|
Dopamine Receptor
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Others
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PD 128907 is a D3 receptor ligand with activities of activating dopamine receptors, inhibiting cell firing, and inhibiting dopamine release. The active (+) enantiomer of PD 128907 has high affinity and selectivity for rat D3 dopamine receptors. PD 128907 inhibits cell firing in the ventral tegmental area and substantia nigra pars compacta with EC50 values of 33nM and 38nM, respectively. PD 128907 also inhibits dopamine release in the caudate putamen with an EC50 of 66nM. However, the selective D2 receptor antagonist L-741,626 has high affinity for receptors activated by PD 128907, indicating that the effects of PD 128907 are more likely on D2 autoreceptors rather than D3 dopamine receptor subtypes.
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- HY-B0843S
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Isotope-Labeled Compounds
Fungal
|
Infection
|
Metalaxyl- 13C6 is the 13C-labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).
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- HY-119775
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Others
|
Others
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U92016A is a potent and selective agonist of the 5-HT1A receptor, with activities such as high affinity binding to the 5-HT1A receptor in vitro, causing a decrease in body temperature in vivo, and high potency and high intrinsic activity as an agonist in single-cell firing studies.
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-
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- HY-113316A
-
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Endogenous Metabolite
Opioid Receptor
|
Neurological Disease
|
(±)-Salsolinol hydrochloride is the hydrochloride form of (±)-Salsolinol (HY-113316). (±)-Salsolinol hydrochloride is a Dopamine (HY-B0451)-derived endogenous metabolite. (±)-Salsolinol hydrochloride activates μ-opioid receptors (MORs), reduces GABAergic transmission, increases the excitability of dopamine (DA) neurons, and thus accelerates the sustained firing of neurons in the posterior ventral tegmental area (pVTA) .
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- HY-130406
-
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Fungal
|
Infection
|
Benthiavalicarb isopropyl is a fungicide with specific activity against downy mildew and blight. Benthiavalicarb isopropyl is evaluated for use where necessary to control a serious threat to plant health that cannot be treated by other methods, including non-chemical methods. The use of Benthiavalicarb isopropyl can be considered representative of field applications in potatoes. Environmental and human exposures of Benthiavalicarb isopropyl are considered to be negligible .
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-
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- HY-112105
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BX-112
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Others
|
Others
|
Prohexadione (BX-112) calcium is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants .
|
-
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- HY-112105A
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BX-112 free acid
|
Others
|
Others
|
Prohexadione (BX-112 free acid) is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants .
|
-
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- HY-112105R
-
|
Others
|
Others
|
Prohexadione (calcium) (Standard) is the analytical standard of Prohexadione (calcium). This product is intended for research and analytical applications. Prohexadione (BX-112) calcium is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants .
|
-
-
- HY-148502
-
|
mAChR
|
Neurological Disease
|
VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA) .
|
-
-
- HY-100481
-
RPR101048
|
Cholecystokinin Receptor
|
Neurological Disease
|
RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors .
|
-
-
- HY-P3467
-
-
- HY-162376
-
|
Bacterial
|
Infection
|
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice .
|
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- HY-B2011
-
|
Fungal
Mitochondrial Metabolism
Succinate Dehydrogenase
|
Infection
|
Flutolanil is a broad-spectrum fungicide. Flutolanil inhibits mycelial oxygen consumption and succinate dehydrogenase in mitochondria Complex II. Flutolanil causes endocrine disruption and reproductive disorders in zebrafish after long-term exposure. Flutolanil can be used to control the fungal pathogens induced plant disease .
|
-
- HY-B2011R
-
|
Fungal
Mitochondrial Metabolism
Succinate Dehydrogenase
|
Infection
|
Flutolanil (Standard) is the analytical standard of Flutolanil. This product is intended for research and analytical applications. Flutolanil is a broad-spectrum fungicide. Flutolanil inhibits mycelial oxygen consumption and succinate dehydrogenase in mitochondria Complex II. Flutolanil causes endocrine disruption and reproductive disorders in zebrafish after long-term exposure. Flutolanil can be used to control the fungal pathogens induced plant disease .
|
-
- HY-147319
-
|
Others
|
Neurological Disease
|
RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinson’s disease (PD) .
|
-
- HY-157802
-
|
Sodium Channel
|
Neurological Disease
|
LTGO-33 is a potent and selective voltage-gated sodium channel NaV1.8 inhibitor. LTGO-33 inhibits NaV1.8 in the nM potency range and exhibits over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. LTGO-33 exhibits state-independent inhibition with similar potencies on channels in the closed and inactivated conformations. LTGO-33 inhibits native TTX-R NaV1.8 currents in non-human primate and human DRG neurons, where it reduces action potential firing. LTGO-33 can be used for pain disorders research .
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- HY-W013712
-
|
Potassium Channel
|
Neurological Disease
|
GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC50 of 0.76 μM for TREK1. GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D1517
-
|
Fluorescent Dyes/Probes
|
FM 2-10 is a fluorescent dye. FM 2-10 is a less hydrophobic version of FM 1-43 (HY-D1434). FM 2-10 can be used for identifying actively firing neurons and investigating the mechanisms of activity-dependent vesicle cycling .
|
Cat. No. |
Product Name |
Target |
Research Area |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y0978S2
-
|
Boc-Glycine-2- 13C is a 13C-labeled Linuron. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive a
|
-
-
- HY-B0843S
-
|
Metalaxyl- 13C6 is the 13C-labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).
|
-
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