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Results for "

phagocytes

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Antibiotic (3) Apolipoprotein (1) Apoptosis (5) Bacterial (3) Biochemical Assay Reagents (1) c-Fms (1) Calcium Channel (2) CD47 (2) Complement System (1) Drug Metabolite (3) Endogenous Metabolite (2) Epigenetic Reader Domain (2) Flavivirus (2) Formyl Peptide Receptor (FPR) (5) Glucokinase (2) Isotope-Labeled Compounds (1) mTOR (1) NOD-like Receptor (NLR) (2) Parasite (5) PERK (2) PKA (2) Reactive Oxygen Species (ROS) (4) Reference Standards (4) STAT (1) TNF Receptor (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (1) Infection (6) Inflammation/Immunology (19) Metabolic Disease (5) Neurological Disease (11)

By Targets:

Amyloid-β (1)

Antibiotic (3)

Apolipoprotein (1)

Apoptosis (5)

Bacterial (3)

Biochemical Assay Reagents (1)

c-Fms (1)

Calcium Channel (2)

CD47 (2)

Complement System (1)

Drug Metabolite (3)

Endogenous Metabolite (2)

Epigenetic Reader Domain (2)

Flavivirus (2)

Formyl Peptide Receptor (FPR) (5)

Glucokinase (2)

Isotope-Labeled Compounds (1)

mTOR (1)

NOD-like Receptor (NLR) (2)

Parasite (5)

PERK (2)

PKA (2)

Reactive Oxygen Species (ROS) (4)

Reference Standards (4)

STAT (1)

TNF Receptor (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (1)

Infection (6)

Inflammation/Immunology (19)

Metabolic Disease (5)

Neurological Disease (11)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-154921

Lactosylceramide (bovine buttermilk) LacCer (bovine buttermilk)	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a sphingolipid that highly expressed on the plasma membranes of human phagocytes. Lactosylceramide mediates phagocytosis, chemotaxis, and superoxide generation .

HY-159069

Zymosan (ZM), 95%	Biochemical Assay Reagents	Inflammation/Immunology
Zymosan (ZM), 95% is a β-1,3-glucan polysaccharide that can be used as a functional food (as dietary fiber), phagocytic stimulus, and immune potentiator. Zymosan (ZM), 95% increases the levels of lysosomal enzyme secretion, upregulates the leukotriene production of monocytes, and enhances the release of proinflammatory cytokines, IL6 and TNFα, MCP-1, CXCL1, IL8, and MMP9 .

HY-P1117

MMK1	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 is a potent chemotactic and calcium-mobilizing agonist. MMK1 potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 exerts anxiolytic-like activity .

HY-W014225

3-Phenoxybenzoic acid 1 Publications Verification 3-PBA	Apoptosis Reactive Oxygen Species (ROS) Drug Metabolite	Inflammation/Immunology
3-Phenoxybenzoic acid is the metabolite of pyrethroid insecticides. 3-Phenoxybenzoic acid induces immunotoxicity and oxidative stress, and inhibits the phagocytic ability of macrophages .

HY-N1482

Methyl palmitate	Parasite	Inflammation/Immunology
Methyl palmitate, an acaricidal compound occurring in Lantana camara, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects .

HY-P99105

Anselamimab CAEL-101	Apolipoprotein Amyloid-β	Neurological Disease
Anselamimab (CAEL-101) is a chimeric monoclonal antibody for systemic light chain (AL) amyloidosis. Anselamimab can promote phagocytic destruction and subsequent clearance of amyloid deposits. Anselamimab can be used in the research of amyloidosis .

HY-N10255

Trypacidin	Parasite	Infection
Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process .

HY-P1117A

MMK1 TFA	Formyl Peptide Receptor (FPR) Calcium Channel	Neurological Disease Inflammation/Immunology
MMK1 TFA is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC₅₀s of <2 nM and >10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity .

HY-158363

CSF1R-IN-25	c-Fms	Neurological Disease Inflammation/Immunology Cancer
CSF1R-IN-25 (compound 36) is an orally effective CSF1R inhibitor. CSF1R-IN-25 can be used to study cancer, inflammation, and neurodegeneration .

HY-W014225S

3-Phenoxybenzoic acid-13C6 3-PBA-¹³C₆	Isotope-Labeled Compounds Apoptosis Reactive Oxygen Species (ROS) Drug Metabolite	Inflammation/Immunology
3-Phenoxybenzoic acid- ¹³C₆ is the ¹³C₆ labeled 3-Phenoxybenzoic acid. 3-Phenoxybenzoic acid is the metabolite of pyrethroid insecticides. 3-Phenoxybenzoic acid induces immunotoxicity and oxidative stress, and inhibits the phagocytic ability of macrophages .

HY-W014225R

3-Phenoxybenzoic acid (Standard) 3-PBA (Standard)	Reference Standards Apoptosis Reactive Oxygen Species (ROS) Drug Metabolite	Inflammation/Immunology
3-Phenoxybenzoic acid (Standard) is the analytical standard of 3-Phenoxybenzoic acid. This product is intended for research and analytical applications. 3-Phenoxybenzoic acid is the metabolite of pyrethroid insecticides. 3-Phenoxybenzoic acid induces immunotoxicity and oxidative stress, and inhibits the phagocytic ability of macrophages .

HY-N1482S1

Methyl palmitate-d31	Parasite	Inflammation/Immunology
Methyl palmitate-d₃₁ is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects .

HY-W339757

Dioctanoylphosphatidic acid sodium	mTOR Endogenous Metabolite	Cancer
Dioctanoylphosphatidic acid sodium functions as a modulator of phagocyte respiratory burst, acts as a precursor to diacylglycerol and lysophosphatidic acid, and influences the phosphorylation of the mammalian target of rapamycin (mTOR) while enhancing the viability of gallbladder carcinoma cells treated with histone deacetylase inhibitors (HDACIs); it is derived from glycerophospholipid through the action of phospholipase D.

HY-N1482S

Methyl palmitate-13C16	Parasite	Inflammation/Immunology
Methyl palmitate- ¹³C₁₆ is the ¹³C labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects .

HY-N1482R

Methyl palmitate (Standard)	Parasite Reference Standards	Inflammation/Immunology
Methyl palmitate (Standard) is the analytical standard of Methyl palmitate. This product is intended for research and analytical applications. Methyl palmitate, an acaricidal compound occurring in Lantana camara, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects .

HY-14926A

Levonadifloxacin (arginine) hydrate (S)-(-)-Nadifloxacin (arginine) hydrate; WCK-771A (arginine) hydrate	Antibiotic Bacterial	Infection
Levonadifloxacin (arginine) hydrate is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin (arginine) hydrate shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .

HY-P1291

PKI 14-22 amide,myristoylated 1 Publications Verification	PKA Epigenetic Reader Domain Flavivirus	Infection Neurological Disease
PKI 14-22 amide, myristoylated is a selective, cAMP-dependent, competitive PKA inhibitor with K_i=~36 nM. The myristoylation modification of PKI 14-22 amide, myristoylated makes it more permeable to cell membranes and blood-brain barriers than the precursor molecule. PKI 14-22 amide, myristoylated can block the phosphorylation of cAMP-dependent downstream targets (such as CREB). PKI 14-22 amide, myristoylated can prevent the development of morphine analgesic tolerance in mice, and also inhibits protein translation and negative-strand RNA synthesis of Zika virus. PKI 14-22 amide, myristoylated can be used in research fields such as opioid tolerance mechanisms and antiviral drugs .

HY-P1291A

PKI 14-22 amide,myristoylated TFA 1 Publications Verification	PKA Epigenetic Reader Domain Flavivirus	Infection Neurological Disease
PKI 14-22 amide, myristoylated TFA is a selective, cAMP-dependent, competitive PKA inhibitor with K_i=~36 nM. The myristoylation modification of PKI 14-22 amide, myristoylated TFA makes it more permeable to cell membranes and blood-brain barriers than the precursor molecule. PKI 14-22 amide, myristoylated TFA can block the phosphorylation of cAMP-dependent downstream targets (such as CREB). PKI 14-22 amide, myristoylated TFA can prevent the development of analgesic tolerance in mice, and also inhibits protein translation and negative-strand RNA synthesis of Zika virus. PKI 14-22 amide, myristoylated TFA can be used in research fields such as opioid tolerance mechanisms and antiviral drugs .

HY-14926

Levonadifloxacin (S)-(-)-Nadifloxacin; WCK 771	Antibiotic Bacterial	Infection
Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .

HY-B1521

Aluminum Hydroxide 3 Publications Verification	NOD-like Receptor (NLR)	Cardiovascular Disease Inflammation/Immunology
Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines .

HY-P990006

Duvakitug TEV-48574	TNF Receptor	Inflammation/Immunology
Duvakitug (TEV-48574) is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD) .

HY-P5469

WRW4-OH	Formyl Peptide Receptor (FPR)	Others
WRW4-OH is a biological active peptide. (This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.)

HY-151132

Glutaminyl cyclases-IN-1 IsoQC-IN-1	CD47	Cancer
Glutaminyl cyclases-IN-1 (IsoQC-IN-1) is a potent glutaminyl cyclases (QC) inhibitor with IC₅₀ values of 12 nM and 73 nM for human QC and isoQC, respectively. Glutaminyl cyclases-IN-1 can selectively interfere with the interaction of CD47/SIRPα through isoQC inhibition, and enhances the increased phagocytic activity of both THP-1 and U937 macrophages .

HY-14926R

Levonadifloxacin (Standard) (S)-(-)-Nadifloxacin (Standard); WCK 771 (Standard)	Reference Standards Antibiotic Bacterial	Infection
Levonadifloxacin (Standard) is the analytical standard of Levonadifloxacin. This product is intended for research and analytical applications. Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes[1].

HY-P990033

Anzurstobart CC-95251; BMS-986351	CD47	Cancer
Anzurstobart (CC-95251; BMS-986351) is a high-affinity, fully human monoclonal anti-SIRPα antibody that blocks the binding of CD47 to SIRPα. Anzurstobart enhances macrophage phagocytic activity against DLBCL cell lines in co-culture models when combined with the antibody Rituximab (HY-P9913). Anzurstobart has the potential for solid and hematologic malignancies research .

HY-B1521R

Aluminum Hydroxide (Standard)	NOD-like Receptor (NLR) Reference Standards	Inflammation/Immunology
Aluminum Hydroxide (Standard) is the analytical standard of Aluminum Hydroxide. This product is intended for research and analytical applications. Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines .

HY-P3257B

ADP-Specific glucokinase, thermococcus litoralis ADP-Dependent hexokinase, thermococcus litoralis	Glucokinase	Neurological Disease Metabolic Disease Cancer
ADP-Specific glucokinase, thermococcus litoralis is an ADP-specific glucose kinase expressed in thermophilic archaea. ADP-Specific glucokinase, thermococcus litoralis can catalyze glucose into glucose-6-phosphate, which promotes glycolysis. ADP-Specific glucokinase, thermococcus litoralis can activate T cells and enhance the phagocytic activity of macrophages. ADP-Specific glucokinase, thermococcus litoralis can be used in research on metabolic diseases, neurological disorders, and tumors .

HY-P3257A

ADP-specific glucokinase, pyrococcus furiosus ADP-dependent hexokinase, pyrococcus furiosus	Glucokinase	Neurological Disease Metabolic Disease Cancer
ADP-Specific glucokinase, pyrococcus furiosus is an ADP-specific glucose kinase expressed in thermophilic archaea. ADP-Specific glucokinase, pyrococcus furiosus can catalyze glucose into glucose-6-phosphate, which promotes glycolysis. ADP-Specific glucokinase, pyrococcus furiosus can activate T cells and enhance the phagocytic activity of macrophages. ADP-Specific glucokinase, pyrococcus furiosus can be used in research on metabolic diseases, neurological disorders, and tumors .

HY-160901

CP-289,503	Complement System	Inflammation/Immunology
CP-289,503 is an inhibitor of the complement C5a receptor with an IC50 of 1 μM. C5a acts as an activator of leukocytes and phagocytes during complement system activation. The C5a receptor can bind to C5a, which can stimulate the upregulation of cell surface integrins and degranulation of inflammatory cells, leading to endothelial cell damage. C5a receptor inhibitors can block C5a signaling and inhibit a variety of inflammatory diseases .

HY-P1120A

WKYMVm TFA	Formyl Peptide Receptor (FPR) PERK Apoptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
WKYMVm (TFA) is a selective formylpeptide receptor 2 (FPR2) agonist. WKYMVm has a powerful anti-inflammatory effect that can reduce lung injury and spinal cord injury. WKYMVm ameliorates obesity by regulating lipid metabolism and leptin signaling. WKYMVm is involved in the regulation of immune cells by activating FPRs, and WKYMVm can promote the chemotactic migration of immune cells and inhibit the apoptosis of phagocytes. In addition, WKYMVm may play a favorable or unfavorable role in tumors, depending on the type of tumor .

HY-P1120

WKYMVm	Formyl Peptide Receptor (FPR) PERK Apoptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
WKYMVm is a selective formylpeptide receptor 2 (FPR2) agonist. WKYMVm has a powerful anti-inflammatory effect that can reduce lung injury and spinal cord injury. WKYMVm ameliorates obesity by regulating lipid metabolism and leptin signaling. WKYMVm is involved in the regulation of immune cells by activating FPRs. WKYMVm can promote the chemotactic migration of immune cells and inhibit the apoptosis of phagocytes. In addition, WKYMVm may play a favorable or unfavorable role in tumors, depending on the type of tumor .

HY-113509B

15(R)-Lipoxin A4 15-epi-LXA4	STAT	Neurological Disease Inflammation/Immunology
15(R)-Lipoxin A4 (15-epi-LXA4) is a STAT-6 activator and a lipid-derived lipoxin-type specialized pro-resolving mediator (SPM) that plays a role in promoting inflammation resolution and regulating immune cell function. 15(R)-Lipoxin A4 can improve the phagocytic function of microglia and exhibits anti-inflammatory activity. In Alzheimer's disease (AD) mouse models, 15(R)-Lipoxin A4 improves AD-like pathology. 15(R)-Lipoxin A4 holds potential for use in inflammation and neurodegenerative disease research .

HY-15130

DL-O-Phosphoserine	Endogenous Metabolite	Metabolic Disease
DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of serine racemase and phagocytosis. O-phospho-L-serine inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development .

Cat. No.	Product Name	Type