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Results for "

polynucleotide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (3) Liposome (2) Phosphatase (1) Phosphorylase (1)
By Research Areas:	Cancer (2) Infection (1) Metabolic Disease (2)
Oligonucleotides:	Cationic Lipids (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Recombinant Proteins

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137817

BCH001	DNA/RNA Synthesis	Metabolic Disease
BCH001, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging .

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium	DNA/RNA Synthesis	Others
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-153137

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate 304O13	Liposome	Cancer
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .

HY-D0178

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 2 Publications Verification	Biochemical Assay Reagents	Others
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

HY-100683

A12B4C3	Phosphatase	Cancer
A12B4C3 is a potent *human polynucleotide* kinase/phosphatase (hPNKP) inhibitor with an IC₅₀** value of 0.06 μM. A12B4C3 has antiproliferative activity against cancer cells. A12B4C3 can also enhance the radiosensitivity of certain cancer cells .

HY-P2844

Polynucleotide kinase	DNA/RNA Synthesis	Metabolic Disease
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-114582

Lexitropsin	DNA Alkylator/Crosslinker	Others
Lexitropsin is a netropsin derivative which is determined the binding and specificity properties in interaction with DNA and synthetic polynucleotides .

HY-151510

A2-Iso5-4DC19	Liposome	Others
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

HY-W541025

Deoxyribonucleic acid	Biochemical Assay Reagents	Others
Deoxyribonucleic acid is a polymer made of two polynucleotide chains wrapped around each other to form a double helix. Deoxyribonucleic acid is found in all dividing cells and is an essential constituent of the chromosomes .

HY-W552525

Deoxyadenosine diphosphate sodium	Phosphorylase	Infection
Deoxyadenosine diphosphate sodium is a nucleoside diphosphate, in which the nucleoside is deoxyadenosine. Deoxyadenosine diphosphate sodium participates in DNA synthesis and repair. Deoxyadenosine diphosphate sodium acts as the inhibitor of polynucleotide phosphorylase, interfers with the polymerization of ADP and CDP .

Cat. No.	Product Name	Type

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium	Gene Sequencing and Synthesis
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-153137

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate 304O13	Drug Delivery
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .

HY-D0178

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 2 Publications Verification	Biochemical Assay Reagents
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

2 Publications Verification

Biochemical Assay Reagents

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

HY-151510

A2-Iso5-4DC19	Drug Delivery
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

HY-W541025

Deoxyribonucleic acid	Gene Sequencing and Synthesis
Deoxyribonucleic acid is a polymer made of two polynucleotide chains wrapped around each other to form a double helix. Deoxyribonucleic acid is found in all dividing cells and is an essential constituent of the chromosomes .

Cat. No.	Compare	Product Name	Species	Source

HY-P71620

	PNKP Protein, Human (His-SUMO) 2''(3'')-polynucleotidase; 2'(3')-polynucleotidase; Bifunctional polynucleotide phosphatase/kinase; DEM 1; DEM1; polynucleotide kinase-3''-phosphatase	Human	E. coli
	PNKP protein plays a key role in DNA damage repair through NHEJ and BER pathways. Its dual catalytic activity includes removal of the 3'-phosphate group from the DNA backbone and phosphorylation of the 5'-hydroxyl group, ensuring compatibility of DNA ends during extension and ligation. PNKP Protein, Human (His-SUMO) is the recombinant human-derived PNKP protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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Cat. No.	Product Name		Classification

HY-153137

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate 304O13		Cationic Lipids
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .

HY-151510

A2-Iso5-4DC19		Cationic Lipids
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

HY-160582

MR-2-93-3 RML-1		Cationic Lipids
MR-2-93-3 is a long-chain fatty acid that can be used to deliver polynucleotides .

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