Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate (Synonyms: 304O13)

Cat. No.: HY-153137: FAQs
Data Sheet Handling Instructions

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Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example.

For research use only. We do not sell to patients.

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate Chemical Structure

CAS No. : 1566559-80-5

Size	Price	Stock	Quantity
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Purity & Documentation
References
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Description

Molecular Weight

951.54

Formula

C₅₇H₁₁₄N₄O₆

CAS No.

1566559-80-5

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(CCN(CCN(CCN(CCC(OCCCCCCCCCCCCC)=O)C)CCN(CCC(OCCCCCCCCCCCCC)=O)C)C)OCCCCCCCCCCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

Ethanol : ≥ 100 mg/mL (105.09 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0509 mL	5.2546 mL	10.5093 mL
5 mM	0.2102 mL	1.0509 mL	2.1019 mL
10 mM	0.1051 mL	0.5255 mL	1.0509 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Anderson, et al. Amine-containing lipid nanoparticles for delivery of siRNA. World Intellectual Property Organization, WO2014028487 A1. 2014-02-20.

[2]. Whitehead KA, Dorkin JR, Vegas AJ, et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nat Commun. 2014;5:4277. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	1.0509 mL	5.2546 mL	10.5093 mL	26.2732 mL
	5 mM	0.2102 mL	1.0509 mL	2.1019 mL	5.2546 mL
	10 mM	0.1051 mL	0.5255 mL	1.0509 mL	2.6273 mL
	15 mM	0.0701 mL	0.3503 mL	0.7006 mL	1.7515 mL
	20 mM	0.0525 mL	0.2627 mL	0.5255 mL	1.3137 mL
	25 mM	0.0420 mL	0.2102 mL	0.4204 mL	1.0509 mL
	30 mM	0.0350 mL	0.1752 mL	0.3503 mL	0.8758 mL
	40 mM	0.0263 mL	0.1314 mL	0.2627 mL	0.6568 mL
	50 mM	0.0210 mL	0.1051 mL	0.2102 mL	0.5255 mL
	60 mM	0.0175 mL	0.0876 mL	0.1752 mL	0.4379 mL
	80 mM	0.0131 mL	0.0657 mL	0.1314 mL	0.3284 mL
	100 mM	0.0105 mL	0.0525 mL	0.1051 mL	0.2627 mL

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate1566559-80-5304O13LiposomeInhibitorinhibitorinhibit

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