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Results for "

pyridyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) Aminopeptidase (1) Bacterial (3) Biochemical Assay Reagents (6) COX (1) Cytochrome P450 (2) Drug Intermediate (5) Drug Metabolite (2) Endogenous Metabolite (3) Fluorescent Dye (4) Glucocorticoid Receptor (1) Isotope-Labeled Compounds (2) Nucleoside Antimetabolite/Analog (1) Parasite (1) Reverse Transcriptase (1) ROCK (1) Small Interfering RNA (siRNA) (1) TGF-β Receptor (1) TMV (1) Transketolase (1) Vasopressin Receptor (1)
By Research Areas:	Cancer (3) Endocrinology (2) Infection (3) Inflammation/Immunology (5) Metabolic Disease (1)
Oligonucleotides:	Nucleosides and their Analogs (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135367

pyCTZ pyridyl CTZ	Fluorescent Dye	Others
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing .

HY-W019817

*4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol* NNAL	Endogenous Metabolite	Cancer
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a significant metabolite of the carcinogenic nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is linked to the development of lung cancer in smokers.

HY-W009906

*2-(2′-Pyridyl)benzimidazole*	Aminopeptidase	Inflammation/Immunology
2-(2’-Pyridyl)benzimidazole is a potentially tridentate ligand that can form stable complexes with various transition metal ions. 2-(2’-Pyridyl)benzimidazole can be used as an anti-inflammatory agent and an inhibitor of Escherichia coli methionine aminopeptidase .

HY-W017463

*trans-3-(3-Pyridyl)acrylic acid*	TMV	Infection
trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV) .

HY-164794

Pyridyl disulfide-Dexamethasone	Glucocorticoid Receptor	Inflammation/Immunology
Pyridyl disulfide-Dexamethasone is a Dexamethasone (HY-14648) modified with pyridyl disulfide, which can be used for the synthesis of targeted peptide steroid conjugates .

HY-135367B

pyCTZ hydrochloride pyridyl CTZ hydrochloride	Fluorescent Dye	Others
pyCTZ (Pyridyl CTZ) hydrochloride, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ hydrochloride generates strong blue bioluminescence in the presence of luciferases. pyCTZ hydrochloride can be used for aequorin-based calcium sensing .

HY-135367A

pyCTZ TFA pyridyl CTZ TFA	Fluorescent Dye	Others
pyCTZ (Pyridyl CTZ) TFA, a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ TFA generates strong blue bioluminescence in the presence of luciferases. pyCTZ TFA can be used for aequorin-based calcium sensing .

HY-139129

*N-(3-Pyridyl)indomethacinamide*	COX	Inflammation/Immunology
N-(3-Pyridyl)indomethacinamide is a derivative of Indomethacin (HY-14397). N-(3-Pyridyl)indomethacinamide is a COX2 inhibitor .

HY-116232

*2-(3-Pyridyl)-benzimidazole*	Cytochrome P450
2-(3-Pyridyl)-benzimidazole is an Aminopyrine N-Demethylase inhibitor .

HY-W012428

*2-(3-Pyridyl)-4-methyl-thiazole-5-carboxylic acid*	Drug Intermediate	Others
2-(3-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

HY-114756

*2-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid*	Drug Intermediate	Others
2-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W019817S1

*4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d3*	Isotope-Labeled Compounds	Others
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d₃ is the deuterium labeled 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-W009401

*Boc-Ala(4-pyridyl)-OH*	Amino Acid Derivatives	Others
Boc-Ala(4-pyridyl)-OH is an alanine derivative .

HY-W127817

*Sn(IV) meso-tetra (4-pyridyl) porphine dichloride*	Biochemical Assay Reagents	Others
Sn(IV) meso-Tetra (4-Pyridyl) Porphine Dichloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W329522

*Ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate*	Drug Intermediate	Others
Ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.

HY-16339

N3PT 1 Publications Verification N3-pyridyl thiamine	Transketolase	Cancer
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an K_d value of 22 nM (Apo-TK, transketolase lacking bound thiamine) .

HY-W003985

*N-Boc-3-(2-pyridyl)-L-alanine*	Amino Acid Derivatives	Others
N-Boc-3-(2-pyridyl)-L-alanine is an alanine derivative .

HY-W335656

*6-Methyl-2-pyridyl* 2-acetamido-2-deoxy-b-D-thioglucopyranoside**	Biochemical Assay Reagents	Others
6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is used for glucose content determination.

HY-154575

*2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine*	Nucleoside Antimetabolite/Analog	Cancer
2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-135368

8pyDTZ 3 Publications Verification	Fluorescent Dye	Others
8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging .

HY-P4010

*Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin*	Vasopressin Receptor	Others
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor .

HY-112362

*3-(4-Pyridyl)indole* Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout	ROCK	Inflammation/Immunology
3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC₅₀ of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay .

HY-114799

*2-(4-Pyridyl)-4-methyl-thiazole-5-carboxylic acid* 4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid	Drug Intermediate	Others
2-(4-Pyridyl)-4-methyl-thiazole-5-carboxylic acid (4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W009934

*2-Phenyl-2-(2-pyridyl)acetonitrile* α-Phenyl-2-pyridineacetonitrile	Drug Metabolite	Endocrinology
2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion .

HY-W044805

*2-Amino-4-(4-pyridyl)-thiazole* 4-Pyridin-4-yl-thiazol-2-ylamine	Drug Intermediate	Others
2-Amino-4-(4-pyridyl)-thiazole (4-Pyridin-4-yl-thiazol-2-ylamine) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-148180

Antimycobacterial agent-4	Bacterial Parasite	Infection
Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line .

HY-W004126

2-Iodopyridine 2-pyridyl iodide	Biochemical Assay Reagents	Others
2-Iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W001990

2-Piperazinopyridine 1-(Pyridin-2-yl)piperazine	Biochemical Assay Reagents	Others
1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-164793

TGFBR1-IN-2	TGF-β Receptor Cytochrome P450 Bacterial	Infection
TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis .

HY-W009934R

*2-Phenyl-2-(2-pyridyl)acetonitrile (Standard)*	Drug Metabolite	Endocrinology

HY-113159R

Docosapentaenoic acid (22n-3) (Standard) Clupanodonic acid (Standard)	Endogenous Metabolite	Metabolic Disease
4-Dimethylaminopyridine (Standard) is the analytical standard of 4-Dimethylaminopyridine. This product is intended for research and analytical applications. N-(4-pyridyl)dimethylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-161436

TPA-dT	Small Interfering RNA (siRNA)	Others
TPA-dT is a thymidine analog with a tris[(2-pyridyl)methyl]amine (TPA) group. TPA-dT can be used to modify siRNAs. The TPA-modified siRNAs remain functionally inactive and is incapable of silencing gene expression until the TPA moiety is removed upon exposure to Cu(I) .

HY-W075425

5,10,15,20-Tetra(pyridin-2-yl)porphyrin meso-Tetrakis(2-pyridyl)porphine	Biochemical Assay Reagents	Others
5,10,15,20-Tetra(pyridin-2-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-126477S

NNK-d4 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone-d₄	Endogenous Metabolite	Others
NNK-d₄ is the deuterium labeled NNK[1].

HY-158705

SAINT-2	Others	Others
SAINT-2 is a cationic lipid with gene transfection activity and is a pyridyl lipid analog. Molecular membranes prepared by SAINT-2 can interact with plasmids to form lipid complexes. After the complex is taken up by cells, the plasmid dissociates from the lipid complex under the action of DOPE and the plasmid translocates across the endosome and/or nuclear membrane. Thus, SAINT-2 effectively transfers small oligonucleotides into cells .

HY-Y0743S

1-(Pyridin-2-yl)ethan-1-one-d6 Methyl 2-pyridyl ketone-d₆	Isotope-Labeled Compounds	Others
1-(Pyridin-2-yl)ethan-1-one-d₆ is deuterated labeled 3,5-Dimethyl-2-vinylpyrazine.

HY-W075433

5,15-Diphenyl-10,20-di(pyridin-4-yl)porphyrin 5,15-Di(4-pyridyl)-10,20-diphenylporphyrin	Biochemical Assay Reagents	Others
5,15-Diphenyl-10,20-di(pyridin-4-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-161364

Antibacterial agent 200	Bacterial	Inflammation/Immunology
Antibacterial agent 200 (pyridyl HH 7), a unique hydrazyl hydroxycoumarin (HH), has strong antibacterial efficacy and broad antibacterial spectrum with MIC values ranging from 0.5 to 32 μg/mL for Gram-positive and Gram-negative bacteria. Antibacterial agent 200 exhibits a good inhibition against Pseudomonas aeruginosa 27853 with a low MIC value of 0.5 μg/mL. Antibacterial agent 200 can eradicate the integrity of bacterial membrane, result in the leakage of intracellular proteins, and interact with bacterial DNA gyrase via non-covalent binding .

HY-15350

Trovirdine hydrochloride LY 300046 hydrochloride	Reverse Transcriptase	Others
Trovirdine hydrochloride, a phenethylthiazolylthiourea (PETT) derivative, is an HIV reverse transcriptase (RT) non-nucleoside inhibitor (NNI). A novel computer model of the RT/NNI binding pocket revealed spatial gaps around Trovirdine hydrochloride's pyridyl ring. Docking studies suggested that replacing this planar ring with a nonplanar piperidinyl or piperazinyl ring could better occupy the binding pocket, enhancing anti-HIV activity. Synthesized heterocyclic compounds based on this modification demonstrated greater potency than Trovirdine hydrochloride, effectively inhibiting HIV replication at nanomolar concentrations without cytotoxicity in infected peripheral blood mononuclear cells .

Cat. No.	Product Name	Type

HY-135367

pyCTZ pyridyl CTZ	Fluorescent Dyes/Probes
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing .

2-Iodopyridine 2-pyridyl iodide	Biochemical Assay Reagents
2-Iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

2-Piperazinopyridine 1-(Pyridin-2-yl)piperazine	Indicators
1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

5,10,15,20-Tetra(pyridin-2-yl)porphyrin meso-Tetrakis(2-pyridyl)porphine	Biochemical Assay Reagents
5,10,15,20-Tetra(pyridin-2-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

*Sn(IV) meso-tetra (4-pyridyl) porphine dichloride*	Biochemical Assay Reagents
Sn(IV) meso-Tetra (4-Pyridyl) Porphine Dichloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113159R

Docosapentaenoic acid (22n-3) (Standard) Clupanodonic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite	Endogenous Metabolite
4-Dimethylaminopyridine (Standard) is the analytical standard of 4-Dimethylaminopyridine. This product is intended for research and analytical applications. N-(4-pyridyl)dimethylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Chemical Structure

HY-W019817S1

*4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d3*
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol-d₃ is the deuterium labeled 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-126477S

NNK-d4
NNK-d₄ is the deuterium labeled NNK[1].

HY-Y0743S

1-(Pyridin-2-yl)ethan-1-one-d6
1-(Pyridin-2-yl)ethan-1-one-d₆ is deuterated labeled 3,5-Dimethyl-2-vinylpyrazine.

Cat. No.	Product Name		Classification

HY-154575

*2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine*		Nucleosides and their Analogs
2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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pyridyl

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products