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Results for "

the yeast Candida albicans

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

4

Peptides

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N11772
    Mutanocyclin

    		Fungal Infection
    Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .
    Mutanocyclin
  • HY-W012444
    Glyceryl 1-monooctanoate

    		Antibiotic Fungal Infection
    Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria .
    Glyceryl 1-monooctanoate
  • HY-N3138
    Ombuoside

    		Bacterial Infection
    Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.Ombuoside has antimicrobial activity against several strains of gram-positive and gram-negative bacteria and the yeast Candida albicans . Ombuoside has antioxidant effects by scavenging free radicals and ROS .
    Ombuoside
  • HY-124701
    Filastatin

    		Fungal Infection
    Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect .
    Filastatin
  • HY-P10304A
    Cyclo(Arg-Pro) TFA

    Cyclo(Pro-Arg) TFA

    		 Fungal Infection
    Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) TFA is a chitinase inhibitor. Cyclo(Arg-Pro) TFA inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) TFA inhibits the morphological change of Candida albicans from yeast form to filamentous form .
    Cyclo(Arg-Pro) TFA
  • HY-163462
    Poacic acid

    		Fungal Infection
    Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants .
    Poacic acid
  • HY-P3916
    GVLSNVIGYLKKLGTGALNAVLKQ

    		Bacterial Infection Inflammation/Immunology
    GVLSNVIGYLKKLGTGALNAVLKQ is an antimicrobial peptide with 24-amino acid. GVLSNVIGYLKKLGTGALNAVLKQ can potentially form α-helix. GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) has activity against Gram-negative, Gram-positive bacteria and the yeast Candida albicans .
    GVLSNVIGYLKKLGTGALNAVLKQ
  • HY-125735
    Sch725674

    		Bacterial Infection
    Sch725674 is a macrolide compound with antimicrobial activity against brewer's yeast and Candida albicans, with MICs of 8 and 32 μg/ml .
    Sch725674
  • HY-P10304C
    Cyclo(L-Pro-D-Arg)

    		Fungal Infection
    Cyclo(Arg-dPro) is an inhibitor of chitinase. Cyclo(Arg-Pro) inhibits the cell separation of Saccharomyces cerevisiae but does not affect its growth. Cyclo(Arg-Pro) inhibits the transition of Candida albicans from yeast to filamentous morphology.
    Cyclo(L-Pro-D-Arg)
  • HY-P10304
    Cyclo(Arg-Pro)

    Cyclo(Pro-Arg)

    		 Fungal Others
    Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .
    Cyclo(Arg-Pro)
  • HY-N7626
    Eleutherol

    		Fungal Glycosidase Infection
    Eleutherol is a naphthalene isolated from E. americana with antifungal activities . Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL . Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM .
    Eleutherol
  • HY-116686
    Inz-1

    		Cytochrome P450 Fungal Infection
    Inz-1 is a potent and selective mitochondrial cytochrome bc1 inhibitor for yeast (IC50=8.092 μM) over humans (IC50=45.320 μM). Inz-1 reverses Fluconazole (HY-B0101) or other triazole antifungals’ resistance in the pathogenic fungus Candida albicans .
    Inz-1
  • HY-P1629
    Temporin A

    		Bacterial Fungal Antibiotic Infection
    Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .
    Temporin A
  • HY-A0132
    N-Acetyl-D-glucosamine
    1 Publications Verification

    N-Acetyl-2-amino-2-deoxy-D-glucose

    		 Endogenous Metabolite Drug Derivative Drug Isomer Interleukin Related Metabolic Disease Inflammation/Immunology Cancer
    N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits .
    N-Acetyl-D-glucosamine
  • HY-159585
    CYP51-IN-20

    		Cytochrome P450 Fungal Infection
    CYP51-IN-20 (compound 5b) is an inhibitor of CYP51 and has antifungal activity. CYP51-IN-20 has a significant inhibitory effect on Candida albicans ATCC 10231, downregulates ERG11 (Cyp51) gene expression, and significantly reduces the yeast-to-hyphae morphological transition. CYP51-IN-20 can synergize with Voriconazole (HY-76200) to occupy the entire CYP51 binding site and exert a synergistic inhibitory effect in the Glechoma moth model .
    CYP51-IN-20

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