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Results for "

thiophenes

" in MedChemExpress (MCE) Product Catalog:

30

Inhibitors & Agonists

4

Biochemical Assay Reagents

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148431
    Antimicrobial agent-14

    		Bacterial Infection
    Antimicrobial agent-14, a benzyl thiophene sulfonamide derivative is an antimicrobial agent, with a MIC of 200 μM against Campylobacter coli ATCC33559. Antimicrobial agent-14 can be used for the research of bacterial foodborne gastroenteritis .
    Antimicrobial agent-14
  • HY-120553
    B-355252

    		Apoptosis Neurological Disease
    B355252, a phenoxy thiophene sulfonamide small molecule, is a potent NGF receptor agonist. B355252 potentiates NGF-induced neurite outgrowth. B355252 protects ischemic neurons from neuronal loss by attenuating DNA damage, reducing ROS production and the LDH level, and preventing neuronal apoptosis. B355252 has anti-apoptotic effects in glutamate-induced excitotoxicity, as well as in a murine hippocampal cell line (HT22) model of Parkinson disease (PD) .
    B-355252
  • HY-W004615R
    Thiophene-3-carboxylic acid (Standard)

    		Biochemical Assay Reagents Others
    Thiophene-3-carboxylic acid (Standard) is the analytical standard of Thiophene-3-carboxylic acid. This product is intended for research and analytical applications. Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Thiophene-3-carboxylic acid (Standard)
  • HY-117145
    Thiophene-2

    		Bacterial Infection
    Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 μM, and has potent anti-tuberculosis activity .
    Thiophene-2
  • HY-132475S
    rac-Duloxetine-d3 oxalate

    		Isotope-Labeled Compounds Neurological Disease
    rac Duloxetine 3-Thiophene Isomer-d3 Oxalate is a stable isotope of Duloxetine.
    rac-Duloxetine-d3 oxalate
  • HY-151581
    HCVcc-IN-1

    		Virus Protease Infection
    HCVcc-IN-1 is a benzothiazole-2-thiophene S-glycoside derivative with low toxic and antiviral activity .
    HCVcc-IN-1
  • HY-W004615
    Thiophene-3-carboxylic acid

    		Biochemical Assay Reagents Others
    Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Thiophene-3-carboxylic acid
  • HY-N3795
    Thiophene E

    Echinoynethiophene A; Thiophene A dio

    		 Others Others
    Thiophene E (Echinoynethiophene A) is a natural product .
    Thiophene E
  • HY-151588
    Anticancer agent 90

    		Virus Protease Cancer
    Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498) .
    Anticancer agent 90
  • HY-151592
    Anticancer agent 91

    		Antibiotic Cancer
    Anticancer agent 91 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. Anticancer agent 91 has high inhibition against the two cell line from CNS cancer (SF-539 and SNB-75) .
    Anticancer agent 91
  • HY-151587
    Anticancer agent 89

    		Others Cancer
    Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5) .
    Anticancer agent 89
  • HY-B0973
    Dibenzothiophene

    DBT; Diphenylene sulfide

    		 Others Others
    Dibenzothiophene is an organic synthesis intermediate consisting of two benzene rings fused to a central thiophene ring.
    Dibenzothiophene
  • HY-150053
    JNK-IN-11

    		JNK Neurological Disease
    JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease .
    JNK-IN-11
  • HY-151589
    HCVcc-IN-2

    		Virus Protease Infection Cancer
    HCVcc-IN-2 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. HCVcc-IN-2 has high inhibition against the three cell line from CNS cancer (SF-539 and SNB-75), colon cancer (HCT-116), and renal cancer (A498) .
    HCVcc-IN-2
  • HY-12384
    Tenosal

    		Others Inflammation/Immunology
    Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties.
    Tenosal
  • HY-148548
    p-HTAA

    		Amyloid-β Neurological Disease
    p-HTAA is a pentamer hydrogen thiophene acetic acid. p-HTAA specifically labels Aβ deposits in the mice living brain .
    p-HTAA
  • HY-W159102
    8CN

    		Parasite Infection
    8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis .
    8CN
  • HY-163521
    Neuraminidase-IN-19

    		Influenza Virus Cancer
    Neuraminidase-IN-19 (compound 5n) is an inhibitor (IC50: 0.13 μM) of neuraminidase with a thiophene ring (neuraminidase) and has anticancer activity .
    Neuraminidase-IN-19
  • HY-W002251
    Benzo[b]thiophene-3-carbaldehyde

    		Biochemical Assay Reagents Others
    Benzo[b]thiophene-3-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Benzo[b]thiophene-3-carbaldehyde
  • HY-147951
    COX-2/5-LOX-IN-3

    		COX Lipoxygenase Inflammation/Immunology
    COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases .
    COX-2/5-LOX-IN-3
  • HY-B0973R
    Dibenzothiophene (Standard)

    		Others Others
    Dibenzothiophene (Standard) is the analytical standard of Dibenzothiophene. This product is intended for research and analytical applications. Dibenzothiophene is an organic synthesis intermediate consisting of two benzene rings fused to a central thiophene ring.
    Dibenzothiophene (Standard)
  • HY-117817
    Ranelic acid

    		Endogenous Metabolite Metabolic Disease
    Ranelic acid is an organic acid with metal cation chelating activity. Ranelic acid can be used to inhibit osteoporosis and increase bone mineral density. Ranelic acid derivatives exhibit highly substituted thiophene ring structures .
    Ranelic acid
  • HY-14175
    Begacestat

    GSI-953

    		 γ-secretase Neurological Disease
    Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) for the treatment of Alzheimer's disease .
    Begacestat
  • HY-N2048
    2,2':5',2''-Terthiophene

    α-​Terthiophene; α-Terthienyl; Trithiophene

    		 Bacterial Antibiotic Infection
    2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.
    2,2':5',2''-Terthiophene
  • HY-13769
    TPT-260

    TPU260

    		 Others Neurological Disease
    TPT-260(TPU260) is a thiophene thiourea derivative with molecule weight 260.00 in free base form; There is no formal name yet, we temporally call this molecule as TPT-260.
    TPT-260
  • HY-59299
    3-Bromothiophene

    3-Bromothiophene

    		 Biochemical Assay Reagents Others
    3-Bromothiophene is a bromine atom-substituted 3-halogenated thiophene with electrochemical stability, small porosity, and high π-π* lowest transition energy. 3-Bromothiophene is often used as a conductive polymer monomer .
    3-Bromothiophene
  • HY-138161
    JR14a
    2 Publications Verification

    		 Complement System Inflammation/Immunology
    JR14a is a potent thiophene antagonist of human complement C3a receptor. JR14a shows selectivity for the human C3a receptor over C5a receptor. JR14a can suppress C3aR-mediated inflammation .
    JR14a
  • HY-148481
    USP7-IN-10

    		Deubiquitinase Cancer
    USP7-IN-10 (compound 1) is a potent ubiquitin-specific protease 7 (USP7) inhibitor, with an IC50 of 13.39 nM .
    USP7-IN-10
  • HY-104027
    ML402
    1 Publications Verification

    		 Potassium Channel Neurological Disease
    ML402, a thiophene-carboxamide, is a selective K2P2.1(TREK-1) and K2P10.1(TREK-2) activator. ML402 is inactive against K2P4.1(TRAAK) .
    ML402
  • HY-124987
    MRS4458

    		Endogenous Metabolite Inflammation/Immunology
    MRS4458 is a P2Y14 receptor antagonist with anti-inflammatory activity. MRS4458 mediates inflammatory activity by activating the motility of neutrophils. The design of MRS4458 is based on the interaction with the P2Y14 receptor and optimized by molecular dynamic simulation. MRS4458 performs well in terms of shape and complementarity with the receptor. The prediction that the 5-phenyl group of MRS4458 is substituted with thiophene is generally consistent with empirical results. The biological activity of MRS4458 was verified by fluorescence assay, showing its potent antagonistic effect .
    MRS4458

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