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Results for "

thymidine analogue

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (2) Bacterial (1) CMV (2) DNA/RNA Synthesis (4) HSV (1) Isotope-Labeled Compounds (1) Nucleoside Antimetabolite/Analog (23) Orthopoxvirus (2) Phosphatase (3) PROTAC Linkers (1)
By Research Areas:	Cancer (8) Endocrinology (1) Infection (11)
Click Chemistry:	PROTAC Synthesis (1) Azide (2) Alkynes (1)
Oligonucleotides:	Nucleosides and their Analogs (19)

Inhibitors & Agonists

Biochemical Assay Reagents

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0307

Idoxuridine 5 Publications Verification 5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd	Phosphatase Orthopoxvirus	Infection Cancer
Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC₅₀ value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.

HY-13578

Brivudine 1 Publications Verification Bromovinyldeoxyuridine; BVDU	CMV	Infection Cancer
Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.

HY-W190976

5-Vinyl-2'-deoxyuridine 5-VINYL-DURD	DNA/RNA Synthesis Apoptosis	Cancer
5-Vinyl-2'-deoxyuridine (5-VINYL-DURD), a thymidine analogue, is incorporated into cellular DNA during DNA replication. 5-Vinyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and induces DNA damage leads to apoptosis in human cultured cells .

HY-B0307A

Idoxuridine hydrate 5-Iodo-2′-deoxyuridine hydrate; 5-IUdR hydrate; IdUrd hydrate	Phosphatase	Infection Cancer
Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) hydrate is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC₅₀ value of 4.3 μM .

HY-B0307R

Idoxuridine (Standard)	Phosphatase Orthopoxvirus	Infection Cancer
Idoxuridine (Standard) is the analytical standard of Idoxuridine. This product is intended for research and analytical applications. Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC₅₀ value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.

HY-114247

FMAU	Nucleoside Antimetabolite/Analog	Others
FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-134795

5-Carboxymethylaminomethyluridine	Nucleoside Antimetabolite/Analog	Others
5-Carboxymethylaminomethyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152639

2’-Chlorothymidine	Nucleoside Antimetabolite/Analog	Others
2’-Chlorothymidine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152875

5-Carboxymethyluridine	Nucleoside Antimetabolite/Analog	Others
5-Carboxymethyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-13578R

Brivudine (Standard)	CMV	Infection Cancer
Brivudine (Standard) is the analytical standard of Brivudine. This product is intended for research and analytical applications. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.

HY-152434

5-Hydroxymethyl-arauridine	Nucleoside Antimetabolite/Analog	Others
5-Hydroxymethyl-arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-W394106

5-Hydroxymethyl uridine	Nucleoside Antimetabolite/Analog	Others
5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152790

5-(2-Hydroxyethyl)uridine	Nucleoside Antimetabolite/Analog	Others
5-(2-Hydroxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152543

5-[3-[(Trifluoroacetyl)amino]propyl]uridine	Nucleoside Antimetabolite/Analog	Others
5-[3-[(Trifluoroacetyl)amino]propyl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-107025

Cf1743	Others	Infection
Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC₅₀ of 3.3 μM for VZV thymidine kinase (TK) .

HY-W393317

5-Methoxycarbonylmethyl-2'-O-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Methoxycarbonylmethyl-2'-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152823

5-Benzylaminocarbonyl-2’-O-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Benzylaminocarbonyl-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152391

3’-beta-C-Methyl-5-methyluridine	Nucleoside Antimetabolite/Analog	Others
3’-beta-C-Methyl-5-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152450

5-Hydroxymethyl-2’-β-C-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Hydroxymethyl-2’-β-C-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152781

5’(R)-C-Methyl-5-methyluridine	Nucleoside Antimetabolite/Analog	Others
5’(R)-C-Methyl-5-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152799

5-Naphthyl-beta-methylaminocarbony-2’-O-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Naphthyl-beta-methylaminocarbony-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152612

2’-Deoxy-2’-fluoro-5-hydroxymethyl arabinouridine	Nucleoside Antimetabolite/Analog	Others
2’-Deoxy-2’-fluoro-5-hydroxymethyl arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152820

2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine	Nucleoside Antimetabolite/Analog	Others
2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152879

5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152801

5-Naphthyl-β-methylaminocarbony-3’-O-acetyl-2’-O-methyluridine	Nucleoside Antimetabolite/Analog	Others
5-Naphthyl-β-methylaminocarbony-3’-O-acetyl-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-W353804

2′-Deoxy-β-L-uridine	Nucleoside Antimetabolite/Analog	Infection
2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme, shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase .

HY-105953

Froxiprost ONO-995	Others	Endocrinology
Froxiprost (ONO-995) is a PGF2α (HY-12956) analogue. Froxiprost stimulates thymidine uptake, 1,2 diacylglycerol (1,2-DAG) accumulation, and phosphorylcholine formation in osteoblast-like MC3T3-E1 cells .

HY-152676

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione	Nucleoside Antimetabolite/Analog	Others
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-16740

Eprociclovir A-5021	DNA/RNA Synthesis	Infection
Eprociclovir is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir can be used in studies interfered with by sensitive viruses .

HY-16740A

Eprociclovir potassium A-5021 potassium	DNA/RNA Synthesis	Infection
Eprociclovir potassium is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir potassium is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir potassium is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir potassium can be used in studies interfered with by sensitive viruses .

HY-16740B

Eprociclovir sodium A-5021 sodium	DNA/RNA Synthesis	Infection
Eprociclovir sodium is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir sodium is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir sodium is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir sodium can be used in studies interfered with by sensitive viruses .

HY-152523

5-(Azidomethyl) arauridine	Nucleoside Antimetabolite/Analog	Others
5-(Azidomethyl) arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl) arauridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-17422S1

Acyclovir-d4 Aciclovir-d₄; Acycloguanosine-d₄	Isotope-Labeled Compounds HSV Bacterial Apoptosis Antibiotic	Infection Cancer
Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-152580

5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine	Nucleoside Antimetabolite/Analog	Others
5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118411

5-Ethynyl-2'-deoxyuridine Maximum Cited Publications 15 Publications Verification	PROTAC Linkers	Cancer
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152525

5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine	Nucleoside Antimetabolite/Analog	Others
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

5-Hydroxymethyl uridine	Biochemical Assay Reagents
5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

Cat. No.	Product Name	Chemical Structure

HY-17422S1

Acyclovir-d4
Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

Cat. No.	Product Name		Classification

HY-118411

5-Ethynyl-2'-deoxyuridine 10+ Cited Publications		Alkynes PROTAC Synthesis
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152523

5-(Azidomethyl) arauridine		Azide
5-(Azidomethyl) arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl) arauridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152525

5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine		Azide
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-152639

2’-Chlorothymidine		Nucleosides and their Analogs
2’-Chlorothymidine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152875

5-Carboxymethyluridine		Nucleosides and their Analogs
5-Carboxymethyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152434

5-Hydroxymethyl-arauridine		Nucleosides and their Analogs
5-Hydroxymethyl-arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152790

5-(2-Hydroxyethyl)uridine		Nucleosides and their Analogs
5-(2-Hydroxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152543

5-[3-[(Trifluoroacetyl)amino]propyl]uridine		Nucleosides and their Analogs
5-[3-[(Trifluoroacetyl)amino]propyl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152823

5-Benzylaminocarbonyl-2’-O-methyluridine		Nucleosides and their Analogs
5-Benzylaminocarbonyl-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152391

3’-beta-C-Methyl-5-methyluridine		Nucleosides and their Analogs
3’-beta-C-Methyl-5-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152450

5-Hydroxymethyl-2’-β-C-methyluridine		Nucleosides and their Analogs
5-Hydroxymethyl-2’-β-C-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152781

5’(R)-C-Methyl-5-methyluridine		Nucleosides and their Analogs
5’(R)-C-Methyl-5-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152799

5-Naphthyl-beta-methylaminocarbony-2’-O-methyluridine		Nucleosides and their Analogs
5-Naphthyl-beta-methylaminocarbony-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152612

2’-Deoxy-2’-fluoro-5-hydroxymethyl arabinouridine		Nucleosides and their Analogs
2’-Deoxy-2’-fluoro-5-hydroxymethyl arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152820

2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine		Nucleosides and their Analogs
2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152879

5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyluridine		Nucleosides and their Analogs
5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152801

5-Naphthyl-β-methylaminocarbony-3’-O-acetyl-2’-O-methyluridine		Nucleosides and their Analogs
5-Naphthyl-β-methylaminocarbony-3’-O-acetyl-2’-O-methyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-W353804

2′-Deoxy-β-L-uridine		Nucleosides and their Analogs
2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme, shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase .

HY-152676

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione		Nucleosides and their Analogs
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-152523

5-(Azidomethyl) arauridine		Nucleosides and their Analogs
5-(Azidomethyl) arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl) arauridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152580

5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine		Nucleosides and their Analogs
5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152525

5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine		Nucleosides and their Analogs
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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