2. Neuronal Signaling
  3. Sigma Receptor
  4. Sigma-1 receptor antagonist 6

Sigma-1 receptor antagonist 6 (Compound 12) is an antagonist of the Sigma-1 receptor (σ1R). Sigma-1 receptor antagonist 6 exerts a robust antiallodynic effect by antagonizing σ1R. Sigma-1 receptor antagonist 6 can be used in neuropathic pain animal models to alleviate mechanical allodynia induced by paclitaxel (HY-B0015).

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Sigma-1 receptor antagonist 6 Chemical Structure

Sigma-1 receptor antagonist 6 Chemical Structure

CAS No. : 1335032-28-4

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Sigma-1 receptor antagonist 6 Related Antibodies

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Description

Sigma-1 receptor antagonist 6 (Compound 12) is an antagonist of the Sigma-1 receptor (σ1R). Sigma-1 receptor antagonist 6 exerts a robust antiallodynic effect by antagonizing σ1R. Sigma-1 receptor antagonist 6 can be used in neuropathic pain animal models to alleviate mechanical allodynia induced by paclitaxel (HY-B0015)[1].

Molecular Weight

502.65

Formula

C32H34N6
CAS No.
SMILES

C#CCN(C)C1=NC(NCCCC2CCN(CC3=CC=CC=C3)CC2)=C(C#N)C(C4=CC=CC=C4)=C1C#N
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Sigma-1 receptor antagonist 6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sigma-1 receptor antagonist 61335032-28-4Sigma Receptorneuropathic painInhibitorinhibitorinhibit

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