SN-38 (Standard)

Cat. No.: HY-13704R Purity: ≥98%: FAQs
Handling Instructions

Molarity Calculator

SN-38 (Standard) is the analytical standard of SN-38. This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254).

For research use only. We do not sell to patients.

SN-38 (Standard) Chemical Structure

CAS No. : 86639-52-3

Size	Price	Stock
5 mg	USD 43	Ask For Quote & Lead Time
10 mg	USD 65	Ask For Quote & Lead Time
25 mg	USD 117	Ask For Quote & Lead Time
50 mg	USD 175	Ask For Quote & Lead Time
100 mg	USD 263	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Description	SN-38 (Standard) is the analytical standard of SN-38 . This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254).
Molecular Weight	392.40
Formula	C₂₂H₂₀N₂O₅
CAS No.	86639-52-3
SMILES	O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C2)=O
Structure Classification	Alkaloids Quinoline Alkaloids
Initial Source	Plants Leguminosae Samanea saman (Jacq.) Merr. Plants Labiatae
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

SN-38 (Standard) Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SN-38 (Standard)86639-52-3Drug MetaboliteTopoisomeraseADC CytotoxinAutophagyADC PayloadInhibitorinhibitorinhibit

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SN-38 (Standard)

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